DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment hzg and Ctdp1

DIOPT Version :9

Sequence 1:	NP_001261912.1	Gene:	hzg / 39748	FlyBaseID:	FBgn0036556	Length:	352	Species:	Drosophila melanogaster
Sequence 2:	NP_080571.2	Gene:	Ctdp1 / 67655	MGIID:	1926953	Length:	960	Species:	Mus musculus

Alignment Length:	167	Identity:	45/167 - (26%)
Similarity:	79/167 - (47%)	Gaps:	34/167 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    96 DQQRYLLPQVRLTDMHRK---CMVIDLDETLVHSSFKPIPNADFIVPVEIDGTVH--------QV 149
            ||||          :||.   .:::|||:||:|::.:..|.      :...|..|        .:
Mouse   173 DQQR----------LHRNRKLVLMVDLDQTLIHTTEQHCPQ------MSNKGIFHFQLGRGEPML 221

  Fly   150 YVLKRPHVDEFLQKMGELYECVLFTASLAKYADPVADLLD-KWNVFRAR-LFRESCV--YYRGNY 210
            :...|||..:||:|:.:|||..:||.....||..:|..|| :..:|..| |.|:.|:  :.:...
Mouse   222 HTRLRPHCKDFLEKIAKLYELHVFTFGSRLYAHTIAGFLDPEKKLFSHRILSRDECIDPFSKTGN 286

  Fly   211 IKDLNRLGRDLQKIVIVDNSPASYIFHPDNAVPVKSW 247
            :::|...|..:  :.|:|:....:.|.| |.:.||.:
Mouse   287 LRNLFPCGDSM--VCIIDDREDVWKFAP-NLITVKKY 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hzg	NP_001261912.1	HIF-SF_euk	112..270	CDD:274055	40/151 (26%)
Ctdp1	NP_080571.2	biotinyl_domain	27..111	CDD:133459
		FCP1_euk	177..323	CDD:131304	41/153 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	331..580
		BRCT	637..706	CDD:237994
		FCP1_C	706..960	CDD:286402
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	770..834
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	854..948
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5190
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900