DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment hzg and CTDSP1

DIOPT Version :9

Sequence 1:	NP_001261912.1	Gene:	hzg / 39748	FlyBaseID:	FBgn0036556	Length:	352	Species:	Drosophila melanogaster
Sequence 2:	XP_016860104.1	Gene:	CTDSP1 / 58190	HGNCID:	21614	Length:	409	Species:	Homo sapiens

Alignment Length:	272	Identity:	148/272 - (54%)
Similarity:	174/272 - (63%)	Gaps:	50/272 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 WLGFSGSV--WLPDCPAD--------HAQLTHDVDRL--------------KPQKRGLFHSLLCC 70
            |.|..|||  :.|..|.|        |.:|......|              ||:.||:.|||.||
Human   114 WAGVGGSVFSFSPCGPQDLDAAPRSAHPRLGLAAPELRARWKGDQKSAASQKPRSRGILHSLFCC 178

  Fly    71 WRRNRTKTNQNGTQIDGSTTP----PPL--------PDQQ--RYLLPQVRLTDMHRKCMVIDLDE 121
            ..|:           ||...|    .||        |.|.  :||||:.:..|..:.|:||||||
Human   179 VCRD-----------DGEALPAHSGAPLLVEENGAIPKQTPVQYLLPEAKAQDSDKICVVIDLDE 232

  Fly   122 TLVHSSFKPIPNADFIVPVEIDGTVHQVYVLKRPHVDEFLQKMGELYECVLFTASLAKYADPVAD 186
            |||||||||:.|||||:||||||.|||||||||||||||||:||||:||||||||||||||||||
Human   233 TLVHSSFKPVNNADFIIPVEIDGVVHQVYVLKRPHVDEFLQRMGELFECVLFTASLAKYADPVAD 297

  Fly   187 LLDKWNVFRARLFRESCVYYRGNYIKDLNRLGRDLQKIVIVDNSPASYIFHPDNAVPVKSWFDDV 251
            |||||..|||||||||||::||||:|||:||||||::::|:|||||||:|||||||.. .|....
Human   298 LLDKWGAFRARLFRESCVFHRGNYVKDLSRLGRDLRRVLILDNSPASYVFHPDNAVSA-GWTGTG 361

  Fly   252 TDCELRELIPLF 263
            |..|.:|.:..|
Human   362 TGAETQEGVSPF 373

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hzg	NP_001261912.1	HIF-SF_euk	112..270	CDD:274055	115/152 (76%)
CTDSP1	XP_016860104.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158654
Domainoid	1	1.000	287	1.000	Domainoid score	I1592
eggNOG	1	0.900	-	-		E1_COG5190
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H100834
Inparanoid	1	1.050	314	1.000	Inparanoid score	I2566
Isobase	1	0.950	-	0	Normalized mean entropy	S764
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1176152at2759
OrthoFinder	1	1.000	-	-		FOG0000901
OrthoInspector	1	1.000	-	-		otm41140
orthoMCL	1	0.900	-	-		OOG6_100959
Panther	1	1.100	-	-	LDO	PTHR12210
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1679
SonicParanoid	1	1.000	-	-		X485
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.740