DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment hzg and ctdspl2a

DIOPT Version :9

Sequence 1:	NP_001261912.1	Gene:	hzg / 39748	FlyBaseID:	FBgn0036556	Length:	352	Species:	Drosophila melanogaster
Sequence 2:	NP_001071012.1	Gene:	ctdspl2a / 558181	ZFINID:	ZDB-GENE-061013-647	Length:	469	Species:	Danio rerio

Alignment Length:	182	Identity:	84/182 - (46%)
Similarity:	115/182 - (63%)	Gaps:	3/182 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    92 PPLPDQQRYLLPQVRLTDMHRK--CMVIDLDETLVHSSFKPIPNADFIVPVEIDGTVHQVYVLKR 154
            |||.::|....|.:.|......  .:|:||||||||.|...:.:|....||.....::||||..|
Zfish   268 PPLTEEQLTRKPALPLKTRSTPEFSLVLDLDETLVHCSLNELEDAALTFPVLFQDVIYQVYVRLR 332

  Fly   155 PHVDEFLQKMGELYECVLFTASLAKYADPVADLLD-KWNVFRARLFRESCVYYRGNYIKDLNRLG 218
            |...|||::|.::||.:|||||...|||.:.::|| |..:.|.|||||.||..:||||||||.||
Zfish   333 PFFREFLERMSQIYEIILFTASKKVYADKLLNILDPKKQLVRHRLFREHCVCVQGNYIKDLNILG 397

  Fly   219 RDLQKIVIVDNSPASYIFHPDNAVPVKSWFDDVTDCELRELIPLFEKLSKVD 270
            |||.|.||:||||.::.:...|.:|::|||.|..|.||.:|:|..|||.:::
Zfish   398 RDLSKTVIIDNSPQAFAYQLSNGIPIESWFVDKNDNELLKLVPFLEKLVELN 449

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hzg	NP_001261912.1	HIF-SF_euk	112..270	CDD:274055	78/160 (49%)
ctdspl2a	NP_001071012.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..42
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	73..136
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	181..209
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	231..250
		HIF-SF_euk	290..445	CDD:274055	76/154 (49%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5190
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1176152at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820