DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment hzg and Ctdsp1

DIOPT Version :9

Sequence 1:	NP_001261912.1	Gene:	hzg / 39748	FlyBaseID:	FBgn0036556	Length:	352	Species:	Drosophila melanogaster
Sequence 2:	NP_001121551.1	Gene:	Ctdsp1 / 363249	RGDID:	1305629	Length:	261	Species:	Rattus norvegicus

Alignment Length:	291	Identity:	163/291 - (56%)
Similarity:	206/291 - (70%)	Gaps:	43/291 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDATSIITQVSRDDEQLNVYPSYPNDKDAWLGFSGSVWLPDCPADHAQLTHDVDRLKPQKRGLFH 65
            ||::::|||:|: :|.........:.|.|                       |.: ||:.||:.|
  Rat     1 MDSSAVITQISK-EEARGPLRGKGDQKSA-----------------------VSQ-KPRSRGILH 40

  Fly    66 SLLCCWRRNRTKTNQNGTQIDGSTTPPPLPDQQ---------RYLLPQVRLTDMHRKCMVIDLDE 121
            ||.||..|:      :|..:...:..|.|.::.         :||||:|:..|..:.|:||||||
  Rat    41 SLFCCVCRD------DGEPLPAHSGAPLLVEENGAIPKHTPVQYLLPEVKAQDSDKICVVIDLDE 99

  Fly   122 TLVHSSFKPIPNADFIVPVEIDGTVHQVYVLKRPHVDEFLQKMGELYECVLFTASLAKYADPVAD 186
            |||||||||:.|||||:||||||.|||||||||||||||||:||||:||||||||||||||||||
  Rat   100 TLVHSSFKPVNNADFIIPVEIDGVVHQVYVLKRPHVDEFLQRMGELFECVLFTASLAKYADPVAD 164

  Fly   187 LLDKWNVFRARLFRESCVYYRGNYIKDLNRLGRDLQKIVIVDNSPASYIFHPDNAVPVKSWFDDV 251
            |||||..|||||||||||::||||:|||:||||||::::|:|||||||:|||||||||.||||::
  Rat   165 LLDKWGAFRARLFRESCVFHRGNYVKDLSRLGRDLRRVLILDNSPASYVFHPDNAVPVASWFDNM 229

  Fly   252 TDCELRELIPLFEKLSKVDSVYSVLCNSNQP 282
            :|.||.:|:|.||:||:||.|||||   .||
  Rat   230 SDTELHDLLPFFEQLSRVDDVYSVL---RQP 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hzg	NP_001261912.1	HIF-SF_euk	112..270	CDD:274055	125/157 (80%)
Ctdsp1	NP_001121551.1	HIF-SF_euk	90..249	CDD:274055	126/158 (80%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352662
Domainoid	1	1.000	282	1.000	Domainoid score	I1581
eggNOG	1	0.900	-	-		E1_COG5190
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H100834
Inparanoid	1	1.050	316	1.000	Inparanoid score	I2478
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1176152at2759
OrthoFinder	1	1.000	-	-		FOG0000901
OrthoInspector	1	1.000	-	-		oto96766
orthoMCL	1	0.900	-	-		OOG6_100959
Panther	1	1.100	-	-	LDO	PTHR12210
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X485
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.760