DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment hzg and Ctdnep1

DIOPT Version :9

Sequence 1:	NP_001261912.1	Gene:	hzg / 39748	FlyBaseID:	FBgn0036556	Length:	352	Species:	Drosophila melanogaster
Sequence 2:	XP_017452582.2	Gene:	Ctdnep1 / 287447	RGDID:	1310172	Length:	285	Species:	Rattus norvegicus

Alignment Length:	181	Identity:	80/181 - (44%)
Similarity:	111/181 - (61%)	Gaps:	13/181 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 LPQVRLTDMHRKCMVIDLDETLVHS--------SFKPIPNADFIVPVEIDGTVHQVYVLKRPHVD 158
            |.:.||..:.||.:|:||||||:||        :.:|....|||:.|.||....:.:|.||||||
  Rat    83 LSRNRLAQVKRKILVLDLDETLIHSHHDGVLRPTVRPGTPPDFILKVVIDKHPVRFFVHKRPHVD 147

  Fly   159 EFLQKMGELYECVLFTASLAKYADPVADLLD-KWNVFRARLFRESCVYYRGNYIKDLNRLGRDLQ 222
            .||:.:.:.||.|:||||:..|...|||.|| ..::.:.|.:|:.|....|:|||||:.:..||.
  Rat   148 FFLEVVSQWYELVVFTASMEIYGSAVADKLDNSRSILKRRYYRQHCTLELGSYIKDLSVVHSDLS 212

  Fly   223 KIVIVDNSPASYIFHP----DNAVPVKSWFDDVTDCELRELIPLFEKLSKV 269
            .|||:||||.:|..||    |||:|:||||.|.:|..|..|:|:.:.||.|
  Rat   213 SIVILDNSPGAYRSHPGMGKDNAIPIKSWFSDPSDTALLNLLPMLDALSAV 263

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hzg	NP_001261912.1	HIF-SF_euk	112..270	CDD:274055	77/171 (45%)
Ctdnep1	XP_017452582.2	HIF-SF_euk	93..263	CDD:274055	76/169 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5190
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1176152at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820