DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Hip14 and ERF2

DIOPT Version :9

Sequence 1:	NP_001261910.1	Gene:	Hip14 / 39747	FlyBaseID:	FBgn0259824	Length:	655	Species:	Drosophila melanogaster
Sequence 2:	NP_013347.1	Gene:	ERF2 / 850947	SGDID:	S000004236	Length:	359	Species:	Saccharomyces cerevisiae

Alignment Length:	206	Identity:	59/206 - (28%)
Similarity:	86/206 - (41%)	Gaps:	65/206 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   320 YIIKFFLLGCLYSIFHTI--GKALFDEHLMALL-PL---SVYLATKAW------------FYVTW 366
            ||  |||.|    .|.|:  .|.|:...|:|:: |:   |::.|.|.|            ||..|
Yeast    59 YI--FFLGG----RFRTVKGAKPLWLGVLLAIVCPMVLFSIFEAHKLWHTQNGYKVLVIFFYYFW 117

  Fly   367 LMYIDDAVSFTATVCFLISSLLLWVCFLKSWKGDPGIIRPTR------------EQRFKTIIELS 419
            ::.:                    ..|:::...|||:: |..            .|.:..:|.|.
Yeast   118 VITL--------------------ASFIRTATSDPGVL-PRNIHLSQLRNNYQIPQEYYNLITLP 161

  Fly   420 ERGGIGFE-PASFCSGCLVRRPIRSKHCSVCDRCVARFDHHCPWVGNCIGLKNHSYFMGFLW--- 480
            ....|..: ...:|..|.:.||.||.|||.|:.||...||||.||.||||.:|:.:|:.||.
Yeast   162 THSSISKDITIKYCPSCRIWRPPRSSHCSTCNVCVMVHDHHCIWVNNCIGKRNYRFFLIFLLGAI 226

  Fly   481 ----MLLIMCA 487
                :||..||
Yeast   227 LSSVILLTNCA 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hip14	NP_001261910.1	ANK	52..165	CDD:238125
		Ank_2	52..142	CDD:289560
		ANK repeat	77..108	CDD:293786
		ANK repeat	110..142	CDD:293786
		ANK	114..233	CDD:238125
		Ank_2	116..209	CDD:289560
		ANK repeat	144..175	CDD:293786
		ANK repeat	177..209	CDD:293786
		Ank_5	198..251	CDD:290568
		ANK repeat	212..244	CDD:293786
		zf-DHHC	426..559	CDD:279823	30/70 (43%)
ERF2	NP_013347.1	COG5273	47..359	CDD:227598	59/206 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810