DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hip14 and zdhhc5b

DIOPT Version :9

Sequence 1:	NP_001261910.1	Gene:	Hip14 / 39747	FlyBaseID:	FBgn0259824	Length:	655	Species:	Drosophila melanogaster
Sequence 2:	XP_009289570.1	Gene:	zdhhc5b / 792560	ZFINID:	ZDB-GENE-101117-1	Length:	658	Species:	Danio rerio

Alignment Length:	258	Identity:	78/258 - (30%)
Similarity:	108/258 - (41%)	Gaps:	67/258 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   374 VSFTATVCFLISSLLLWVCFLKSWKG----------------------------DPGIIRPTREQ 410
            |..:|...||:.:..|::||...|..                            |||:.....|.
Zfish    26 VPVSAATAFLVGATTLFLCFTCPWLSEKFSSFIPLYNVVVFLFTLANFCMATFMDPGVFPRAEED 90

  Fly   411 R----------FKTIIELSERGGIGFEPASFCSGCLVRRPIRSKHCSVCDRCVARFDHHCPWVGN 465
            .          :||:    |..||... ..:||.|...||.|..||||||.||..||||||||.|
Zfish    91 EDKEDDFRAPLYKTV----EVRGIQVR-MKWCSTCRFYRPPRCSHCSVCDNCVEEFDHHCPWVNN 150

  Fly   466 CIGLKNHSYFMGFLWMLLIMCAWM-LYGGSKYYVNQCNVRFDDFLGAMRAIGNCDAWVGW--VMG 527
            |||.:|:.||  ||::|.:....| ::|.|..|:.....:.|.....:.....|.|.:.:  |.|
Zfish   151 CIGRRNYRYF--FLFLLSLTVHIMDVFGFSLLYILHHTKQLDLVQSGVTMAVMCVAGLFFVPVAG 213

  Fly   528 NALLHMSWVILLTICQTYQVICLGMTTNERMNRGRYRHFQAKGGHSPFTRGPIQNLVDFLECS 590
            ....|   |:|         :..|.||||::. |::|     ||.:|||.|..:|:...| ||
Zfish   214 LTGFH---VVL---------VARGRTTNEQVT-GKFR-----GGVNPFTHGCFKNIAHVL-CS 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hip14	NP_001261910.1	ANK	52..165	CDD:238125
		Ank_2	52..142	CDD:289560
		ANK repeat	77..108	CDD:293786
		ANK repeat	110..142	CDD:293786
		ANK	114..233	CDD:238125
		Ank_2	116..209	CDD:289560
		ANK repeat	144..175	CDD:293786
		ANK repeat	177..209	CDD:293786
		Ank_5	198..251	CDD:290568
		ANK repeat	212..244	CDD:293786
		zf-DHHC	426..559	CDD:279823	49/135 (36%)
zdhhc5b	XP_009289570.1	DHHC	110..235	CDD:396215	50/140 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810