DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hip14 and zdhhc15b

DIOPT Version :9

Sequence 1:	NP_001261910.1	Gene:	Hip14 / 39747	FlyBaseID:	FBgn0259824	Length:	655	Species:	Drosophila melanogaster
Sequence 2:	NP_001071249.1	Gene:	zdhhc15b / 777734	ZFINID:	ZDB-GENE-061110-106	Length:	332	Species:	Danio rerio

Alignment Length:	243	Identity:	59/243 - (24%)
Similarity:	96/243 - (39%)	Gaps:	83/243 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   344 EHLMALLPLSVYLATKAWFYVTWLMYIDDAVSFTATVCFLISS---------LLLWVCFL----K 395
            :.:.:.:|:.:..:...|.|..::.          .:||:..|         |:..|||:    .
Zfish    11 QRIFSWIPVIIISSVVLWSYYAYVF----------ELCFVTLSNNLGRVTYLLIFHVCFIMFCWT 65

  Fly   396 SWKGDPGIIRP--TREQRF------KTIIELSER-----------------------GGIGFEPA 429
            .||   .|..|  |..::|      |...|:.||                       |.|
Zfish    66 YWK---AIFTPPSTPTKKFHLSYTDKERYEMEERPEVQKQILVDIAKKLPIFTRAQSGAI----- 122

  Fly   430 SFCSGCLVRRPIRSKHCSVCDRCVARFDHHCPWVGNCIGLKNHSYFMGFLWMLLIMCAWMLYGGS 494
            .||..|.|.:|.|..|||||:.||.:.|||||||.||:|..|:.:|:.||...:|.|.::.....
Zfish   123 RFCDRCQVIKPDRCHHCSVCETCVLKMDHHCPWVNNCVGFSNYKFFLLFLSYSMIYCVFIASTVF 187

  Fly   495 KYYVNQCNVRFDDFLGAMRAIGNCDAWVGWV-MGNALLHMSWVILLTI 541
            :|:     ::|               |||.: .|.|..|:.:::.:.:
Zfish   188 QYF-----LKF---------------WVGDLPNGPAKFHVLFLLFVAL 215

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hip14	NP_001261910.1	ANK	52..165	CDD:238125
		Ank_2	52..142	CDD:289560
		ANK repeat	77..108	CDD:293786
		ANK repeat	110..142	CDD:293786
		ANK	114..233	CDD:238125
		Ank_2	116..209	CDD:289560
		ANK repeat	144..175	CDD:293786
		ANK repeat	177..209	CDD:293786
		Ank_5	198..251	CDD:290568
		ANK repeat	212..244	CDD:293786
		zf-DHHC	426..559	CDD:279823	37/117 (32%)
zdhhc15b	NP_001071249.1	zf-DHHC	16..292	CDD:303066	59/238 (25%)
zdhhc15b	NP_001071249.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	305..332
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810