DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hip14 and Zdhhc25

DIOPT Version :9

Sequence 1:	NP_001261910.1	Gene:	Hip14 / 39747	FlyBaseID:	FBgn0259824	Length:	655	Species:	Drosophila melanogaster
Sequence 2:	NP_081582.1	Gene:	Zdhhc25 / 70073	MGIID:	1917323	Length:	279	Species:	Mus musculus

Alignment Length:	166	Identity:	46/166 - (27%)
Similarity:	72/166 - (43%)	Gaps:	45/166 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   351 PLSVYLATKAWFYVT---WLMYIDDAVS--------FTATVCFLISSLLLWVCFLKSWKGDPGII 404
            |:.:..|..||..|.   |:::.|..:.        ....|..|::||.| ...|::...|||.:
Mouse    34 PIGILCAMAAWALVLSGGWVLFRDLLIPSNNMLYIVANGVVFHLLASLAL-ASHLRTMLTDPGSV 97

  Fly   405 ---RPTREQRFKTIIELSERGGIGFEPASFCSGCLVRRPIRSKHCSVCDRCVARFDHHCPWVGNC 466
               .|.                 |.:..|:|:.|....|..:.||:||.||:.:.||||||:.||
Mouse    98 PLGNPP-----------------GPDTVSYCTDCHSAIPRTACHCTVCQRCIRKNDHHCPWINNC 145

  Fly   467 IGLKNHSYFMGF----------LWMLL---IMCAWM 489
            ||..|..||:.|          :.:||   ::|::|
Mouse   146 IGEDNQKYFLLFTMYIGLTSTHVLLLLGIPVLCSYM 181

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hip14	NP_001261910.1	ANK	52..165	CDD:238125
		Ank_2	52..142	CDD:289560
		ANK repeat	77..108	CDD:293786
		ANK repeat	110..142	CDD:293786
		ANK	114..233	CDD:238125
		Ank_2	116..209	CDD:289560
		ANK repeat	144..175	CDD:293786
		ANK repeat	177..209	CDD:293786
		Ank_5	198..251	CDD:290568
		ANK repeat	212..244	CDD:293786
		zf-DHHC	426..559	CDD:279823	28/77 (36%)
Zdhhc25	NP_081582.1	zf-DHHC	109..230	CDD:279823	28/73 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900