DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hip14 and Zdhhc16

DIOPT Version :9

Sequence 1:	NP_001261910.1	Gene:	Hip14 / 39747	FlyBaseID:	FBgn0259824	Length:	655	Species:	Drosophila melanogaster
Sequence 2:	XP_006231465.1	Gene:	Zdhhc16 / 654495	RGDID:	1591893	Length:	377	Species:	Rattus norvegicus

Alignment Length:	332	Identity:	79/332 - (23%)
Similarity:	122/332 - (36%)	Gaps:	105/332 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   291 DKRLRWWSMVACPFTAFYLAGIVFTVNTLYIIKFFLLGCLYSIFHTIGKALFDEHLMALLPL--- 352
            |..:||:             |:||.|  |.|:   |.|.:.:|.:           :.:|||
  Rat    73 DNVIRWF-------------GVVFVV--LVIV---LTGSIVAIAY-----------LCVLPLILR 108

  Fly   353 --SVYLATKAWFYVTWLMYIDDAVSFTATVCFLISSLLLWVCFLKSWKGDPGIIRPTREQRFKTI 415
              ||......:||..|                  :.:|:...:.::....|| ..|.......|:
  Rat   109 TYSVPRLCWHFFYSHW------------------NLILIVFHYYQAITTPPG-YPPQGRNDIATV 154

  Fly   416 IELSERGGIGFEPASFCSGCLVRRPIRSKHCSVCDRCVARFDHHCPWVGNCIGLKNHSYFMGFLW 480
                          |.|..|:..:|.|:.|||:|:|||.:.||||||:.||:|..||.||..|.:
  Rat   155 --------------SICKKCIYPKPARTHHCSICNRCVLKMDHHCPWLNNCVGHYNHRYFFSFCF 205

  Fly   481 MLLIMCAWMLYGGSKYYVNQCNVRFDDFLGAMRAIGNCDAWVGWVMGN---------------AL 530
            .:.:.|.:..||....        |.:...|:..:...|......:.|               .:
  Rat   206 FMTLGCVYCSYGSWDL--------FREAYAAIEKMKQLDKNKLQAIANQTYHQTPPPTFSFRERI 262

  Fly   531 LHMSWVILLTICQTYQ------------VICLGMTTNER-MNRGRYRHFQAKGG--HSPFTRGPI 580
            .|.|.|.|..:|.:..            :|..|.|:.|| :|:...|..||||.  .:|:..|.:
  Rat   263 THKSLVYLWFLCSSVALALGALTMWHAVLISRGETSIERHINKKERRRLQAKGRVFRNPYNYGCL 327

  Fly   581 QNLVDFL 587
            .|...||
  Rat   328 DNWKVFL 334

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hip14	NP_001261910.1	ANK	52..165	CDD:238125
		Ank_2	52..142	CDD:289560
		ANK repeat	77..108	CDD:293786
		ANK repeat	110..142	CDD:293786
		ANK	114..233	CDD:238125
		Ank_2	116..209	CDD:289560
		ANK repeat	144..175	CDD:293786
		ANK repeat	177..209	CDD:293786
		Ank_5	198..251	CDD:290568
		ANK repeat	212..244	CDD:293786
		zf-DHHC	426..559	CDD:279823	43/160 (27%)
Zdhhc16	XP_006231465.1	DHHC	156..305	CDD:396215	42/156 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810