DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hip14 and CG17198

DIOPT Version :9

Sequence 1:	NP_001261910.1	Gene:	Hip14 / 39747	FlyBaseID:	FBgn0259824	Length:	655	Species:	Drosophila melanogaster
Sequence 2:	NP_001287532.1	Gene:	CG17198 / 43110	FlyBaseID:	FBgn0039366	Length:	299	Species:	Drosophila melanogaster

Alignment Length:	336	Identity:	74/336 - (22%)
Similarity:	115/336 - (34%)	Gaps:	128/336 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly   315 TVNTLYIIKFFLLGCLYSIFHTIGKALFDEHLMALLPLSVYLATKAWFYVTWLMYIDDAVSFTAT 379
            ::|...|:.|:.....|.:...:|  ||.:.:..|:             .||::|
  Fly    42 SINVCIILFFYFFEAFYVMPQFLG--LFGQAVHFLV-------------TTWIVY---------- 81

  Fly   380 VCFLISSLLLWVCFLKSWKGDPGIIRPTREQRFKTIIELSERGGIGFEPA-SFCSGCLVRRPIRS 443
              .::.:|.|.|..|.:....|    |..:|..|           |.|.. .||..|....|.||
  Fly    82 --NILENLRLCVTTLNTVDSLP----PQMQQPMK-----------GEEHLWHFCKICQRNVPPRS 129

  Fly   444 KHCSVCDRCVARFDHHCPWVGNCIGLKNHSYFMGFLWMLLIMCAWMLYGGSKYYVNQCNVRFDDF 508
            .||::||.|:.:.||||.:||||:|..|..||:.|.:...|..|..|              ||:|
  Fly   130 WHCNICDACILKRDHHCNFVGNCVGHNNQRYFIWFSFYAAIGSAVAL--------------FDNF 180

  Fly   509 LGAMR-AIGNCDAWVGWVMGNALLHMSWVILLTICQTYQVICLGMTTNERMNRGR------YRHF 566
            :.|.: .:|..|          |:..:::|.                |..||.||      ||
  Fly   181 MLAHKHGVGFFD----------LVKANYIIF----------------NAYMNPGRKELVIFYR-- 217

  Fly   567 QAKGGHSPFTRGPIQNLVDFLECSCFGLVQPKRVDWMNYYDYDAQTHQTIEKEPLLSVDCPDGMA 631
                            :|..|..:.|.::.|..:       :..|....|:...:
  Fly   218 ----------------IVSVLGVNIFAVLFPAAL-------FCTQVVTVIKNSVM---------- 249

  Fly   632 GDHQYVXDKTY 642
              |.|  |:||
  Fly   250 --HDY-SDRTY 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hip14	NP_001261910.1	ANK	52..165	CDD:238125
		Ank_2	52..142	CDD:289560
		ANK repeat	77..108	CDD:293786
		ANK repeat	110..142	CDD:293786
		ANK	114..233	CDD:238125
		Ank_2	116..209	CDD:289560
		ANK repeat	144..175	CDD:293786
		ANK repeat	177..209	CDD:293786
		Ank_5	198..251	CDD:290568
		ANK repeat	212..244	CDD:293786
		zf-DHHC	426..559	CDD:279823	37/134 (28%)
CG17198	NP_001287532.1	zf-DHHC	43..>176	CDD:303066	47/174 (27%)
CG17198	NP_001287532.1	zf-DHHC	111..252	CDD:279823	50/217 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810