DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Hip14 and Zdhhc5

DIOPT Version :9

Sequence 1:	NP_001261910.1	Gene:	Hip14 / 39747	FlyBaseID:	FBgn0259824	Length:	655	Species:	Drosophila melanogaster
Sequence 2:	NP_001034427.1	Gene:	Zdhhc5 / 362156	RGDID:	1589737	Length:	715	Species:	Rattus norvegicus

Alignment Length:	250	Identity:	81/250 - (32%)
Similarity:	112/250 - (44%)	Gaps:	62/250 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   400 DPGIIRPTREQR----------FKTIIELSERGGIGFEPASFCSGCLVRRPIRSKHCSVCDRCVA 454
            ||||.....|..          :||:    |..||... ..:|:.|...||.|..||||||.||.
  Rat    69 DPGIFPRAEEDEDKEDDFRAPLYKTV----EIKGIQVR-MKWCATCRFYRPPRCSHCSVCDNCVE 128

  Fly   455 RFDHHCPWVGNCIGLKNHSYFMGFLWMLLIMCAWM-LYGGSKYYVNQCNVRFDDFLGAMRAIG-- 516
            .||||||||.||||.:|:.||  ||::|.:....| ::|....|| .|::  ::..|...|:.
  Rat   129 EFDHHCPWVNNCIGRRNYRYF--FLFLLSLTAHIMGVFGFGLLYV-LCHI--EELSGVRTAVTMA 188

  Fly   517 -NCDAWVGW--VMGNALLHMSWVILLTICQTYQVICLGMTTNERMNRGRYRHFQAKGGHSPFTRG 578
             .|.|.:.:  |.|....|   |:|         :..|.||||::. |::|     ||.:|||.|
  Rat   189 VMCVAGLFFIPVAGLTGFH---VVL---------VARGRTTNEQVT-GKFR-----GGVNPFTNG 235

  Fly   579 PIQNLVDFLECSCFG---LVQPKRVDWMNYYDYDAQTHQTIE-KEPLLSVDCPDG 629
            ...|:...| ||...   |.:||:             .:||. :.|.|..:..||
  Rat   236 CCNNVSRVL-CSSPAPRYLGRPKK-------------EKTIVIRPPFLRPEVSDG 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hip14	NP_001261910.1	ANK	52..165	CDD:238125
		Ank_2	52..142	CDD:289560
		ANK repeat	77..108	CDD:293786
		ANK repeat	110..142	CDD:293786
		ANK	114..233	CDD:238125
		Ank_2	116..209	CDD:289560
		ANK repeat	144..175	CDD:293786
		ANK repeat	177..209	CDD:293786
		Ank_5	198..251	CDD:290568
		ANK repeat	212..244	CDD:293786
		zf-DHHC	426..559	CDD:279823	50/138 (36%)
Zdhhc5	NP_001034427.1	zf-DHHC	99..224	CDD:279823	51/143 (36%)
Zdhhc5	NP_001034427.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	289..715
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810