DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hip14 and CG17075

DIOPT Version :9

Sequence 1:	NP_001261910.1	Gene:	Hip14 / 39747	FlyBaseID:	FBgn0259824	Length:	655	Species:	Drosophila melanogaster
Sequence 2:	NP_001245821.1	Gene:	CG17075 / 33191	FlyBaseID:	FBgn0031239	Length:	968	Species:	Drosophila melanogaster

Alignment Length:	273	Identity:	68/273 - (24%)
Similarity:	104/273 - (38%)	Gaps:	80/273 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   226 ATAISTLVLK--SKASLDVPN--LRGETPLSMLESQTGAIWIGAKVMDRVKEAALTSQQRRSLLS 286
            |..:.|.|.|  |..|.|.|.  :.||      :::|     ..|.:...:.:.|.|.|  |.::
  Fly    42 AKGVVTPVRKPHSLGSEDSPENIIPGE------QAET-----NKKPLHLCRLSQLVSYQ--SNIA 93

  Fly   287 KLRHDK--RLRWWSMVACPFTAF-YLAGIVFTVNTLYI-IKFF---LLGCLYSIFHTIGKALFDE 344
            .::|.|  ||....:...|...| :|..::|.|.:.:: |..|   :.|.||.:...:.......
  Fly    94 DVQHRKGRRLHGLQLPLHPLQIFGWLVLLLFGVASYWVLIPAFHARIQGPLYGLITGLYLVHIAS 158

  Fly   345 HLMALLPLSVYLATKAWFYVTWLMYIDDAVSFTATVCFLISSLLLWVCFLKSWKGDPGIIRPTRE 409
            ||.|||                   .|.|                          |..:.|..|.
  Fly   159 HLTALL-------------------TDPA--------------------------DKELRRVHRN 178

  Fly   410 QRFKTIIELSERGGIGFEPASFCSGCLVRRPI-RSKHCSVCDRCVARFDHHCPWVGNCIGLKNHS 473
            .|.....:.|:...: .|... |..|.:|... |:||||||::||.:|||||.|:.:|||.:|:.
  Fly   179 DRIVPEFDRSKHSHV-IENGR-CHLCNIRTSSNRTKHCSVCNKCVGKFDHHCKWLNHCIGSRNYV 241

  Fly   474 YFMGFLWMLLIMC 486
            .|        :||
  Fly   242 AF--------LMC 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hip14	NP_001261910.1	ANK	52..165	CDD:238125
		Ank_2	52..142	CDD:289560
		ANK repeat	77..108	CDD:293786
		ANK repeat	110..142	CDD:293786
		ANK	114..233	CDD:238125	2/6 (33%)
		Ank_2	116..209	CDD:289560
		ANK repeat	144..175	CDD:293786
		ANK repeat	177..209	CDD:293786
		Ank_5	198..251	CDD:290568	10/28 (36%)
		ANK repeat	212..244	CDD:293786	7/19 (37%)
		zf-DHHC	426..559	CDD:279823	26/62 (42%)
CG17075	NP_001245821.1	zf-DHHC	199..>282	CDD:279823	25/56 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900