DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hip14 and Zdhhc25

DIOPT Version :9

Sequence 1:	NP_001261910.1	Gene:	Hip14 / 39747	FlyBaseID:	FBgn0259824	Length:	655	Species:	Drosophila melanogaster
Sequence 2:	NP_001034422.1	Gene:	Zdhhc25 / 300323	RGDID:	1598341	Length:	279	Species:	Rattus norvegicus

Alignment Length:	278	Identity:	64/278 - (23%)
Similarity:	96/278 - (34%)	Gaps:	108/278 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly   351 PLSVYLATKAWFYVT---WLMYIDDAVS--------FTATVCFLISSLLLWVCFLKSWKGDPGII 404
            |:.:..|...|..|.   |::..|..:.        ....:..|::||.| |..|::...|||.:
  Rat    34 PIGILCAMATWALVLSGGWVLVRDLLIPSNNMLYIVANGMIFHLLASLAL-VSHLRTMLTDPGSV 97

  Fly   405 ----RPTREQRFKTIIELSERGGIGFEPASFCSGCLVRRPIRSKHCSVCDRCVARFDHHCPWVGN 465
                ||                  |.:..|:|..|....|.|:.||:||.||:.:.|||||||.|
  Rat    98 PLGNRP------------------GPDTVSYCPDCRSAIPKRAAHCAVCKRCIRKNDHHCPWVNN 144

  Fly   466 CIGLKNHSYFMGFLW----------MLL---IMCAWMLYGGSKYYVNQCNVRFDDFLGAMRAIGN 517
            |:|..|..||:.|:.          :||   ::|::                         |.|.
  Rat   145 CVGEDNQKYFLLFIMYIGLSGTHVLLLLGIPVLCSY-------------------------ARGE 184

  Fly   518 CD-----------------AWVGWVMGNALLHMSWVILLTICQTYQVICLGMTTNERMNRGRYRH 565
            .|                 |.:|:|:.:.:|          |.....|....||.|.:.:..
  Rat   185 WDSSSSVSPPAPILFLLLVALMGFVLSSVML----------CTQMCTIYTDKTTTELLYQNT--- 236

  Fly   566 FQAKGGHSPFTRGPIQNL 583
                  |||..|....||
  Rat   237 ------HSPGNRAKCANL 248

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hip14	NP_001261910.1	ANK	52..165	CDD:238125
		Ank_2	52..142	CDD:289560
		ANK repeat	77..108	CDD:293786
		ANK repeat	110..142	CDD:293786
		ANK	114..233	CDD:238125
		Ank_2	116..209	CDD:289560
		ANK repeat	144..175	CDD:293786
		ANK repeat	177..209	CDD:293786
		Ank_5	198..251	CDD:290568
		ANK repeat	212..244	CDD:293786
		zf-DHHC	426..559	CDD:279823	40/162 (25%)
Zdhhc25	NP_001034422.1	zf-DHHC	109..230	CDD:279823	39/155 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900