Protein Alignment Hip14 and Zdhhc14

DIOPT Version :10

• Sequence 1: NP_001261910.1
• Gene: Hip14 / 39747
• FlyBaseID: FBgn0259824
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_666185.3
• Gene: Zdhhc14 / 224454
• MGIID: 2653229
• Length: 489
• Species: Mus musculus
• Alignment Length: 288
• Identity: 74/288 - (25%)
• Similarity: 124/288 - (43%)
• Gaps: 48/288 - (16%)

  Fly   350 LPLSVYLATKAWFYVTWLMYIDDAVSFTATVC-----FLISSLLLWVCFLKSWKGDPGII-RPTR 408
            |.|.:.|.|...|:.....|:.:.::....|.     |.:...||...|     .|||:: |.|.
Mouse    66 LTLILILVTSGLFFAFDCRYLAEKITPAIPVVGGILFFFVMGTLLRTSF-----SDPGVLPRATP 125

  Fly   409 EQRFKTIIELSERGGI---GFEP---------------ASFCSGCLVRRPIRSKHCSVCDRCVAR 455
            ::......::....|.   |:.|               ..:|..|.:.||.|:.|||:||.||.:
Mouse   126 DEAADLERQIDIANGTSSGGYRPPPRTKEVVINGQTVKLKYCFTCKIFRPPRASHCSLCDNCVEQ 190

  Fly   456 FDHHCPWVGNCIGLKNHSYFMGFLWMLLIMCAWMLYGGSKYYVNQCNVRFDDFLGAMRAIGNCDA 520
            |||||||||||:|.:|:.:|..|:..|..:..::......:.:::...:  .||.|::     |:
Mouse   191 FDHHCPWVGNCVGKRNYRFFYMFILSLSFLTVFIFAFVITHVIHRSQQK--GFLDALK-----DS 248

  Fly   521 WVGWVMGNALLHMSWVIL-LTICQTYQVICLGMTTNERMNRGRYRHFQAKGGHSPFTRGPIQNLV 584
            ....:.........|.|: |:...|| :|....||||.: :|.:.:.:.|..::|::.|.|
Mouse   249 PASVLEAVICFFSVWSIIGLSGFHTY-LISSNQTTNEDI-KGSWSNKRGKENYNPYSYGNI---- 307

  Fly   585 DFLECSCFGL---VQPKRVDWMNYYDYD 609
             |..| |..|   :.|..:|...|...|
Mouse   308 -FTNC-CVALCGPISPSLIDRRGYVQPD 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hip14	NP_001261910.1	ANKYR	<52..246	CDD:440430
		ANK repeat	77..108	CDD:293786
		ANK repeat	110..142	CDD:293786
		ANK repeat	144..175	CDD:293786
		ANK repeat	177..209	CDD:293786
		ANK repeat	212..244	CDD:293786
		DHHC	426..559	CDD:396215	43/148 (29%)
Zdhhc14	NP_666185.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	434..454
		DHHC	164..287	CDD:396215	42/131 (32%)
		Atrophin-1	351..>461	CDD:460830