DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hip14 and zdhhc14

DIOPT Version :9

Sequence 1:	NP_001261910.1	Gene:	Hip14 / 39747	FlyBaseID:	FBgn0259824	Length:	655	Species:	Drosophila melanogaster
Sequence 2:	XP_004914695.1	Gene:	zdhhc14 / 100489334	XenbaseID:	XB-GENE-998053	Length:	481	Species:	Xenopus tropicalis

Alignment Length:	286	Identity:	76/286 - (26%)
Similarity:	125/286 - (43%)	Gaps:	44/286 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   350 LPLSVYLATKAWFYVTWLMYIDDAVSFTATVCFLISSLLLWV--CFLKSWKGDPGII-RPTREQR 411
            |.|.:.|.|...|:.....|:  ||..|..:..:...|:.:|  ..|::...|||:: |.|.::.
Frog    58 LTLILILVTSGLFFAFDCPYL--AVKITPAIPVIGGILVFFVMGTLLRTSFSDPGVLPRATPDEA 120

  Fly   412 FKTIIELSERGGI---GFEP---------------ASFCSGCLVRRPIRSKHCSVCDRCVARFDH 458
            .....::....|.   |:.|               ..:|..|.:.||.|:.|||:||.||.||||
Frog   121 ADLERQIDVANGSTSGGYRPPPRTKEVVINGQTVKLKYCFTCKIFRPPRASHCSLCDNCVERFDH 185

  Fly   459 HCPWVGNCIGLKNHSYFMGFLWMLLIMCAWMLYGGSKYYVNQCNVRFDD--FLGAMRAIGNCDAW 521
            ||||||||:|.:|:.:|..|:..|..:..::.    .:.:....:|...  ||.|::     |:.
Frog   186 HCPWVGNCVGKRNYRFFYMFILSLSFLTVFIF----AFVITHVILRSQQSGFLNALK-----DSP 241

  Fly   522 VGWVMGNALLHMSWVIL-LTICQTYQVICLGMTTNERMNRGRYRHFQAKGGHSPFTRGPIQNLVD 585
            ...:.........|.|: |:...|| :|....||||.: :|.:...:.|..::|::.|.|
Frog   242 ASVLEAVVCFFSVWSIVGLSGFHTY-LISSNQTTNEDI-KGSWSSKRGKENYNPYSYGNI----- 299

  Fly   586 FLEC--SCFGLVQPKRVDWMNYYDYD 609
            |..|  :..|.|.|..:|...:...|
Frog   300 FKNCCAALCGPVNPSLIDRRGFVPAD 325

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hip14	NP_001261910.1	ANK	52..165	CDD:238125
		Ank_2	52..142	CDD:289560
		ANK repeat	77..108	CDD:293786
		ANK repeat	110..142	CDD:293786
		ANK	114..233	CDD:238125
		Ank_2	116..209	CDD:289560
		ANK repeat	144..175	CDD:293786
		ANK repeat	177..209	CDD:293786
		Ank_5	198..251	CDD:290568
		ANK repeat	212..244	CDD:293786
		zf-DHHC	426..559	CDD:279823	45/150 (30%)
zdhhc14	XP_004914695.1	DHHC	156..279	CDD:366691	44/133 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910