DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment DNApol-delta and AT5G63960

DIOPT Version :9

Sequence 1:	NP_524099.2	Gene:	DNApol-delta / 39746	FlyBaseID:	FBgn0263600	Length:	1092	Species:	Drosophila melanogaster
Sequence 2:	NP_001190611.1	Gene:	AT5G63960 / 836517	AraportID:	AT5G63960	Length:	1112	Species:	Arabidopsis thaliana

Alignment Length:	1132	Identity:	598/1132 - (52%)
Similarity:	749/1132 - (66%)	Gaps:	84/1132 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 GKRKFNGTSNGHAKKPRNPD------DDEEMGFEAELAAFENSEDMDQTLLMGDG---------- 51
            ||.:..|.|        .|.      |||.|        .|....:|:|||.||.
plant    21 GKHRATGDS--------TPSPAIGTLDDEFM--------MEEDVFLDETLLYGDEDEESLILRDI 69

  Fly    52 PENQTTSERWSRPP--PPELDPSKHNLEFQQLDVENYLGQP----LPGMPGAQIGPVPVVRMFGV 110
            .|.::.|..|:|||  |..|..|: ::.||||::::.:.:.    |||    ..|..|::|||||
plant    70 EERESRSSAWARPPLSPAYLSNSQ-SIIFQQLEIDSIIAESHKELLPG----SSGQAPIIRMFGV 129

  Fly   111 TMEGNSVCCHVHGFCPYFYIEAPSQFEEHHCEKLQKALDQKVIADIRNNKDNVQEAVLMVELVEK 175
            |.|||||||.||||.|||||..|............::|:.::....:|.|  |.:.|..:|:|:|
plant   130 TREGNSVCCFVHGFEPYFYIACPPGMGPDDISNFHQSLEGRMRESNKNAK--VPKFVKRIEMVQK 192

  Fly   176 LNIHGYNGDKKQRYIKISVTLPRFVAAASRLLKKEVIMSEIDFQDCRAFENNIDFDIRFMVDTDV 240
            .:|..|...|.|.::||:|.||..||:...:|.:.:.:..:..:..:.:|:||.|.:|||||.|:
plant   193 RSIMYYQQQKSQTFLKITVALPTMVASCRGILDRGLQIDGLGMKSFQTYESNILFVLRFMVDCDI 257

  Fly   241 VGCNWIELPMGHWRIRNSHSKPLPESRCQIEVDVAFDRFISHEPEGEWSKVAPFRILSFDIECAG 305
            ||.||||:|.|.:: :|:.:.    |.||:|....:...|||..|||:||:||||:|||||||||
plant   258 VGGNWIEVPTGKYK-KNARTL----SYCQLEFHCLYSDLISHAAEGEYSKMAPFRVLSFDIECAG 317

  Fly   306 RKGIFPEAKIDPVIQIANMVIRQGEREPFIRNVFTLNECAPIIGSQVLCHDKETQMLDKW----- 365
            |||.|||||.||||||||:|..|||..||:|||.||..||||:|..|:..:.|.::|..|
plant   318 RKGHFPEAKHDPVIQIANLVTLQGEDHPFVRNVMTLKSCAPIVGVDVMSFETEREVLLAWRVLFL 382

  Fly   366 ------------SAFVREVDPDILTGYNINNFDFPYLLNRAAHLKVRNFEYLGRIKNIRSVIKEQ 418
                        |..:|:|||||:.||||..||.|||:.|||.|.:..|..|||:||.|..:::.
plant   383 PLHYYICITSSSSDLIRDVDPDIIIGYNICKFDLPYLIERAATLGIEEFPLLGRVKNSRVRVRDS 447

  Fly   419 MLQSKQMGRRENQYVNFEGRVPFDLLFVLLRDYKLRSYTLNAVSYHFLQEQKEDVHHSIITDLQN 483
            ...|:|.|.||::....|||..|||:..:.||:||.||:||:||.|||.||||||||||||||||
plant   448 TFSSRQQGIRESKETTIEGRFQFDLIQAIHRDHKLSSYSLNSVSAHFLSEQKEDVHHSIITDLQN 512

  Fly   484 GDEQTRRRLAMYCLKDAYLPLRLLEKLMAIVNYMEMARVTGVPLESLLTRGQQIKVLSQLLRKAK 548
            |:.:||||||:|||||||||.|||:|||.|.||:|||||||||:..||.|||.||||||||||.|
plant   513 GNAETRRRLAVYCLKDAYLPQRLLDKLMFIYNYVEMARVTGVPISFLLARGQSIKVLSQLLRKGK 577

  Fly   549 TKGFIMPSYTSQGSDE-QYEGATVIEPKRGYYADPISTLDFASLYPSIMMAHNLCYTTLVLGGTR 612
            .|..::|:....||:: .||||||:|.:.|:|..||:||||||||||||||:||||.|||   |.
plant   578 QKNLVLPNAKQSGSEQGTYEGATVLEARTGFYEKPIATLDFASLYPSIMMAYNLCYCTLV---TP 639

  Fly   613 EKLRQQENLQDDQVERTPANNYFVKSEVRRGLLPEILESLLAARKRAKNDLKVETDPFKRKVLDG 677
            |.:|:. ||..:.|.:||:...|||..:::|:||||||.||.||||||.|||...||.::.||||
plant   640 EDVRKL-NLPPEHVTKTPSGETFVKQTLQKGILPEILEELLTARKRAKADLKEAKDPLEKAVLDG 703

  Fly   678 RQLALKISANSVYGFTGAQVGKLPCLEISGSVTAYGRTMIEMTKNEVESHYTQANGYENNAVVIY 742
            ||||||||||||||||||.||:|||||||.|||:|||.|||.||..||..:|...||:.||.|||
plant   704 RQLALKISANSVYGFTGATVGQLPCLEISSSVTSYGRQMIEQTKKLVEDKFTTLGGYQYNAEVIY 768

  Fly   743 GDTDSVMVNFGVKTLERSMELGREAAELVSSKFVHPIKLEFEKVYYPYLLINKKRYAGLYFTRPD 807
            ||||||||.|||..:|.:|.|||||||.:|..|:.||||||||||:|||||||||||||.:|.|.
plant   769 GDTDSVMVQFGVSDVEAAMTLGREAAEHISGTFIKPIKLEFEKVYFPYLLINKKRYAGLLWTNPQ 833

  Fly   808 TYDKMDCKGIETVRRDNSPLVANLMNSCLQKLLIERDPDGAVAYVKQVIADLLCNRIDISHLVIT 872
            .:||||.||||||||||..||.||:...|.|:||:||..||...||:.|:|||.||||:|.||||
plant   834 QFDKMDTKGIETVRRDNCLLVKNLVTESLNKILIDRDVPGAAENVKKTISDLLMNRIDLSLLVIT 898

  Fly   873 KELAKT--DYAAKQAHVELAAKMKKRDPGTAPKLGDRVPYVICAAAKNTPAYQKAEDPLYVLENS 935
            |.|.||  ||..|.||.|||.:|:|||..|||.:||||||||..|||...||:::|||:|||:|:
plant   899 KGLTKTGDDYEVKSAHGELAERMRKRDAATAPNVGDRVPYVIIKAAKGAKAYERSEDPIYVLQNN 963

  Fly   936 VPIDATYYLEQQLSKPLLRIFEPILGDNAESILLKGEHTRTRTVVTSKVGGLAGFMTKKTSCLGC 1000
            :|||..||||.|:||||||||||:| .||...||.|.|||:.::.|....|:..|..|:.||:||
plant   964 IPIDPNYYLENQISKPLLRIFEPVL-KNASKELLHGSHTRSISITTPSNSGIMKFAKKQLSCVGC 1027

  Fly  1001 KSLMPKGYEQACLCPHCEPRMSELYQKEVGAKRELEETFSRLWTECQRCQESLHEEVICSNRDCP 1065
            |..:..|    .||..|:.|.:|||.|.|....||||.|.||||:||.||.|||::|:|::||||
plant  1028 KVPISNG----TLCASCKGREAELYCKNVSQVAELEEVFGRLWTQCQECQGSLHQDVLCTSRDCP 1088

  Fly  1066 IFYMRQKVRMDLDNQEKRVLRFGLAEW 1092
            |||.|.|.:.|:     .|.|..|..|
plant  1089 IFYRRMKAQKDM-----AVARQQLDRW 1110

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DNApol-delta	NP_524099.2	PTZ00166	48..1092	CDD:240301	583/1079 (54%)
		DNA_polB_delta_exo	288..517	CDD:99820	142/245 (58%)
		POLBc_delta	564..960	CDD:99916	260/398 (65%)
		zf-C4pol	997..1070	CDD:290959	39/72 (54%)
AT5G63960	NP_001190611.1	PTZ00166	81..1109	CDD:240301	578/1053 (55%)
		DNA_polB_delta_exo	300..546	CDD:99820	142/245 (58%)
		POLBc_delta	595..988	CDD:99916	260/396 (66%)
		zf-C4pol	1024..1093	CDD:290959	39/72 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	536	1.000	Domainoid score	I58
eggNOG	1	0.900	-	-		E1_COG0417
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2014
Inparanoid	1	1.050	1102	1.000	Inparanoid score	I29
OMA	1	1.010	-	-		QHG53777
OrthoDB	1	1.010	-	-		D20210at2759
OrthoFinder	1	1.000	-	-		FOG0001033
OrthoInspector	1	1.000	-	-		oto3799
orthoMCL	1	0.900	-	-		OOG6_101046
Panther	1	1.100	-	-	LDO	PTHR10322
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3678
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840