Protein Alignment DNApol-delta and pola1

DIOPT Version :9

• Sequence 1: NP_524099.2
• Gene: DNApol-delta / 39746
• FlyBaseID: FBgn0263600
• Length: 1092
• Species: Drosophila melanogaster
• Sequence 2: XP_031752562.1
• Gene: pola1 / 100379926
• XenbaseID: XB-GENE-1000548
• Length: 1489
• Species: Xenopus tropicalis
• Alignment Length: 1229
• Identity: 282/1229 - (22%)
• Similarity: 476/1229 - (38%)
• Gaps: 290/1229 - (23%)

  Fly    37 ENSEDMDQTLLMGDGPENQT----TSERWSRPPPPELDPSKHNL----------EFQQLDV-ENY 86
            |:|..|:::..|.....|::    ..|..|.....::|.|:..|          :|..||. |:.
 Frog   309 EDSVKMEESSFMTSAALNESCWDQIDEVESMTTEVQVDSSRLPLVTGADGSQVFKFYWLDAYEDQ 373

  Fly    87 LGQPLPGMPGAQIGPVPVVRMFG----VTMEGNSVCC-HVHGFCPYFYIEAPSQFEEHHCEKLQK 146
            ..||            .||.:||    .|.|....|| .|.......|:     ....:..:|..
 Frog   374 YSQP------------GVVYLFGKVWIETAEAYVSCCVSVKNIERTVYL-----LPRENRVQLST 421

  Fly   147 ALDQKVIADIRNNKDNVQEAVLMVELVEKLNIHGYNGDKKQR--------------YIKISVTLP 197
            ..|..|...:.|......|:|     .||..|..:...|.::              |:::
 Frog   422 GKDTGVPVSMMNVYQEFNESV-----AEKYKIMKFKSKKVEKDYAFEIPDVPASSEYLEV----- 476

  Fly   198 RFVAAASRL---LKKEVIMSEIDFQDCRAFENNIDFDIRFMVDTDVVGCNWIELPMGHWRIRNSH 259
            |:.|.:.:|   ||.|..        ...|..|......|::...:.|.:|:|       |::..
 Frog   477 RYSADSPQLPQDLKGETF--------SHVFGTNTSSLELFLLSRKIKGPSWLE-------IKSPQ 526

  Fly   260 SKPLPESRCQIE--------VDVAFDRFISHEPEGEWSKVAPFRILSFDIECAGRKGIFPEAKI- 315
            ....|.|.|::|        |:|..|           ....|..:||..::..      ..||.
 Frog   527 LSSQPMSWCKVEAVVMRPDQVNVVKD-----------LAPPPVVVLSLSMKTV------QNAKTH 574

  Fly   316 -DPVIQIANMV-----IRQGEREPFIRNVFTL----NECAPIIGSQVLCHD-------------- 356
             :.::.:|.:|     :.:...:|..:..|.:    |:|       :..:|
 Frog   575 QNEIVAMAALVHHKFPLDKAPPQPPFQTHFCVLSKPNDC-------IFPYDFKEAVKRKNANIEI 632

  Fly   357 --KETQMLDKWSAFVREVDPDILTGYNINNFDFPYLLNRAAHLKVRNFEYLGRIKNIRSVIKEQM 419
              .|..:|..:.|.:.::||||:.|::|..||...||.|.:..||..:..:||::  |||:
 Frog   633 ALTERTLLGFFLAKIHKIDPDIIVGHDIYGFDLEVLLQRISSCKVPFWSKIGRLR--RSVM---- 691

  Fly   420 LQSKQMGRRENQYVNFE------GRVPFDLLFVLLRDYKLRSYTLNAVSYHFLQEQK-----EDV 473
               .::|.|.    .|.      ||:..|.........:.:||.|:.:.:..|:.::     |::
 Frog   692 ---PKLGGRS----GFAERNAACGRIICDTEISAKELIRCKSYHLSELVHQILKTERVLMPPENI 749

  Fly   474 HHSIITDLQNGDEQTRRRLAMYCLKDAYLPLRLLEKLMAIVNYMEMA----RVTGVPLESLLTRG 534
            .::......          .:|.|::.:...:.:.::|..:|.:.:|    .:.|..|...|..|
 Frog   750 RNAYSDSAH----------LLYMLENTWTDAKFILQIMCELNVLPLALQITNIAGNVLSRTLMGG 804

  Fly   535 QQIKVLSQLLRKAKTKGFIMPSY------------------TSQGSDEQ------YEGATVIEPK 575
            :..:....||.......||:|..                  |.|..:::      |.|..|:|||
 Frog   805 RSERNEYLLLHAFTENNFIVPDKPVFKKIQQTTVEDDDNMDTDQNKNKKGRKKAAYAGGLVLEPK 869

  Fly   576 RGYYADPISTLDFASLYPSIMMAHNLCYTTLVLGGTREKLRQQENLQDDQVERTPANNYFVKSEV 640
            .|:|...|..|||.||||||:..:|:|:||:    .||....|:....:::...|      .|::
 Frog   870 VGFYDKFILLLDFNSLYPSIIQEYNICFTTV----QREAPTSQKGEDQEEIPELP------HSDL 924

  Fly   641 RRGLLPEILESLLAARKRAKNDLK-VETDPFKRKVLDGRQLALKISANSVYGFTGAQVGKLPCLE 704
            ..|:||..:..|:..|:..|..:| .:.:|......|.||.|||::|||:||..|....:.....
 Frog   925 EMGILPREIRKLVERRRHVKQLMKQPDLNPDLYLQYDIRQKALKLTANSMYGCLGFSYSRFYAKP 989

  Fly   705 ISGSVTAYGRTMIEMTKNEVESHYTQANGYENNAVVIYGDTDSVMVNFGVKTLERSMELGREAAE 769
            ::..||..||.::..||..|:         :.|..||||||||:|:|.....||...:||.....
 Frog   990 LAALVTHQGREILLHTKEMVQ---------KMNLEVIYGDTDSIMINTNCNNLEEVFKLGNRVKS 1045

  Fly   770 LVSSKFVHPIKLEFEKVYYPYLLINKKRYAGLYFTRPDTYD-----KMDCKGIETVRRDNSPLVA 829
            .|:..: ..::::.:.::...||:.||:||.|  |...|.|     |.:.||::.||||...|..
 Frog  1046 EVNKSY-KLLEIDIDGIFKSLLLLKKKKYAAL--TVEPTGDGKYVTKQELKGLDIVRRDWCELAK 1107

  Fly   830 NLMNSCLQKLLIERDPDGAVAYVKQVIADLLCN----RIDISHLVITKELAK--TDYAAKQA--H 886
            ...|..:.::|.::..|..|..:::.:.::..|    .:.||...|.|.|.|  .||..|::  |
 Frog  1108 EAGNYVISQILSDQPRDNIVENIQKKLTEIGENVTNGTVPISQYEINKALTKDPQDYPDKKSLPH 1172

  Fly   887 VELAAKMKKRDPGTAPKLGDRVPYVICAAAKNTPAYQKAEDP--LYVLENSVPIDATYYLEQQLS 949
            |.:|..:..:. |...|.||.:.||||....|..|.|:|..|  |...|| :.||..|||.||:.
 Frog  1173 VHVAMWINSQG-GRKVKAGDTISYVICQDGSNLSASQRAYAPEQLQKQEN-LSIDTQYYLSQQVH 1235

  Fly   950 KPLLRIFEPILGDNAESILL------------KGEHTRTRTVVTSKVGGLAGFM--TKKTSCLGC 1000
            ..:.||.|||  |..:|.|:            ...|.:......:.:||.:...  .|...|...
 Frog  1236 PVVARICEPI--DGIDSALIAMWLGLDPSQFRAHRHHQQDEENDALLGGPSQLTDEEKYRDCERF 1298

  Fly  1001 KSLMPK-GYE------------------QACLCPHCEPR-MSELYQKE----VGAKRELEETFSR 1041
            |...|| |.|                  :.|..|.|:.. :..:.|.:    :..:|.:::.:|.
 Frog  1299 KFFCPKCGTENIYDNVFDGSGLQIEPGLKRCSKPECDASPLDYVIQVQNKLLLDIRRYIKKYYSG 1363

  Fly  1042 LWTECQR--CQESLHEEVICSNRDCPIFYMRQKVRMDLDNQEKRV------LRFGLAEW 1092
             |..|:.  ||.......:..:|:.||.....|..:..:..||.:      .|| :.:|
 Frog  1364 -WLVCEEKTCQNRTRRVPLSFSRNGPICQACTKATLRSEYPEKALYTQLCFYRF-IFDW 1420

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DNApol-delta	NP_524099.2	PTZ00166	48..1092	CDD:240301	278/1216 (23%)
		DNA_polB_delta_exo	288..517	CDD:99820	48/266 (18%)
		POLBc_delta	564..960	CDD:99916	132/417 (32%)
		zf-C4pol	997..1070	CDD:290959	19/98 (19%)
pola1	XP_031752562.1	pol2	59..1243	CDD:273159	247/1046 (24%)
		zf-DNA_Pol	1284..>1433	CDD:401082	26/139 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910