Protein Alignment DNApol-delta and rev3l

DIOPT Version :9

• Sequence 1: NP_524099.2
• Gene: DNApol-delta / 39746
• FlyBaseID: FBgn0263600
• Length: 1092
• Species: Drosophila melanogaster
• Sequence 2: XP_002936975.2
• Gene: rev3l / 100145815
• XenbaseID: XB-GENE-1012630
• Length: 3130
• Species: Xenopus tropicalis
• Alignment Length: 1148
• Identity: 302/1148 - (26%)
• Similarity: 487/1148 - (42%)
• Gaps: 199/1148 - (17%)

  Fly    14 HAKKPRNPDDDEEMGFE----AELAAFENSEDMDQTLLMGDGPENQTTSERWSRPPPPELDPSKH 74
            |...|....|..|..|.    |...|.....|.::.|.....|::...:.......|...:.::.
 Frog  2085 HLASPPPVLDSAEKEFVITACASKPASSGRSDQNELLDSSVSPDSPVLTSWQETLSPDNTNTAED 2149

  Fly    75 NLEFQQLDVENYLGQPLPGMPGAQIGPVPVVRMFGVTMEGNSVCCHVHGFCPYFYIEAPSQ---- 135
            |.:|:..::     .|.|.:   :.|..|.|:.....:...|                |||
 Frog  2150 NKDFKSGNI-----SPTPFL---ECGATPQVKNEPTDLSDLS----------------PSQESRG 2190

  Fly   136 --FEEHHCEKLQKALDQKVIADIRNNKDNVQEAVLMVELVEK------LNIHGYNGDKKQRYIKI 192
              ..:|.|......:::|..|:       ..||:|...|:.:      ....|.|.||.:|.:..
 Frog  2191 KLKSKHTCMHSTPVIERKPEAE-------STEALLCSPLLSEPISQRMSQRRGRNPDKLRRVLLT 2248

  Fly   193 SVTLPRFVAAASRLLKKEVIMSEIDFQDCRAFENNIDFDIRFMVDTDVVGCNWIELPMGHWRIRN 257
            :....:|...|.  ||:|.                                :.||.|    .:.|
 Frog  2249 TQMKNQFATMAQ--LKRET--------------------------------SQIEGP----SLNN 2275

  Fly   258 SHSKPLPESRCQIEVDVAFDRFISHEPEGEWSKVAPFRILSFDIECAGRKGIFPEAKIDPVI--- 319
            |:.       .::.|....|....||       |....::|.::....|:.:.|:.:.||:.
 Frog  2276 SYG-------FKVSVQNLQDAKALHE-------VQHLTLMSMELHARTRRDLEPDPEFDPICALF 2326

  Fly   320 ---------------QIANMVI--------RQGERE-PFIRNVFTLNECAPIIGSQVLCHDKETQ 360
                           |:...:|        ..|.|: ||:..       :.|.|.:|.....|.|
 Frog  2327 YCLSSDSLLSNANKKQVTGAIIVHLEEPSSEGGRRQTPFLAR-------SGITGFEVTYAADEKQ 2384

  Fly   361 MLDKWSAFVREVDPDILTGYNINNFDFPYLLNRAAHLKVRNFEYLGRI---KNIRSVIKEQMLQS 422
            :.:...:.||..|||||.||.:....:.|||.||:.|.|...:.|.|:   ||......|:
 Frog  2385 LFEMLLSLVRRFDPDILLGYEVQMHSWGYLLQRASALNVDLCQQLSRVPDDKNENRFSTEK---- 2445

  Fly   423 KQMGRRENQYVNFEGRVPFDLLFVLLRDYKLRSYTLNAVSYHFLQEQKEDVHHSIITD-LQNGDE 486
            .:.|......:|..||:..::..::..:..|.:||...|::|.|.::........::| ..|..:
 Frog  2446 DEYGADTMSEINIVGRIVLNVWRMMRSEVALTNYTFENVAFHVLHQRFPLFTFRSLSDWFDNRKD 2510

  Fly   487 QTRRRLAMYCLKDAYLPLRLLEKLMAIVNYMEMARVTGVPLESLLTRGQQIKVLSQLLRKAKTKG 551
            ..|.|.|.|.:...:..|::||||..|....|:||:.|:....:||||.|.:|.|.:||.||...
 Frog  2511 VLRWRTADYYMCRVHGSLQVLEKLDLIGRTSELARLFGIQFLHVLTRGSQYRVESMMLRIAKPMN 2575

  Fly   552 FIMPSYTSQGSDEQYEG----ATVIEPKRGYYADPISTLDFASLYPSIMMAHNLCYTTLVLGGTR 612
            :| |...|.....|...    ..|:||:..:|::.|..|||.||||||::|:|.||:|.:  |..
 Frog  2576 YI-PLTPSIQQRSQMRAPQCIPLVMEPESRFYSNCILVLDFQSLYPSIVIAYNYCYSTCL--GNI 2637

  Fly   613 EKLRQQEN-----------------LQDDQVERTPANNYFVKSEVRRGLLPEILESLLAARKRAK 660
            |.|.:.|:                 |:.| :..:|....|||:.||:|:||.:||.:|..|...|
 Frog  2638 ENLGKYEDFKFGCSSLQVPPDLLYQLRHD-ITVSPNGVAFVKACVRKGVLPRMLEEILKTRIMVK 2701

  Fly   661 NDL-KVETDPFKRKVLDGRQLALKISANSVYGFTGAQV-GKLPCLEISGSVTAYGRTMIEMTKNE 723
            ..: |.:.|....::||.|||.||:.||..:|:|.|.. |::||:||..|:....|..:|.....
 Frog  2702 QSMKKYKHDKGLTRLLDARQLGLKLIANVTFGYTAANYSGRMPCVEIGDSIVHKARETLERAIKL 2766

  Fly   724 VESHYTQANGYENNAVVIYGDTDSVMVNFGVKTLERSMELGREAAELVSSKFVHPIKLEFEKVYY 788
            |..  |:..|    |.|:||||||:.|.....|.|:|.::|:|.||.|::....||||:|||||.
 Frog  2767 VND--TKKWG----AKVVYGDTDSMFVLLKGATKEQSFKIGQEIAEAVTATNPKPIKLKFEKVYL 2825

  Fly   789 PYLLINKKRYAGLYFTRPDTYDKM-DCKGIETVRRDNSPLVANLMNSCLQKLLIERDPDGAVAYV 852
            |.:|..||||.|..:...|..|.: |.|||||||||..|.|..::...|:.|...||......||
 Frog  2826 PCVLQTKKRYVGYMYETVDQKDPVFDAKGIETVRRDACPAVGKILERSLKLLFETRDISQIKQYV 2890

  Fly   853 KQVIADLLCNRIDISHLVITKELAKTDYAAKQA----HVELAAKMKKRDPGTAPKLGDRVPYVIC 913
            ::....|:..:..:..|:..||. :..:|.|..    .:||..||...|..:.|::|:||||||.
 Frog  2891 QKQCIKLVEGKASMQDLIFAKEY-RGSFAYKPGACVPALELTRKMVAYDRRSEPRVGERVPYVII 2954

  Fly   914 AAAKNTPAYQKAEDPLYVL-ENSVPIDATYYLEQQLSKPLLRIFEPILGDNA-----ESILLKGE 972
            ..:...|..|....|:.|| ::::.::.|||:.:|:..||.|||. ::|.:.     |...::..
 Frog  2955 YGSPGVPLIQLVRRPIDVLQDHNLRLNGTYYITKQILPPLNRIFS-LIGVDVFSWYDELPRIQKT 3018

  Fly   973 HTRTRTVVTSKVGGLAGFMTKKTSCLGCKSLMPKGYEQACLCPHCEPRMSE---LYQKEVGAKRE 1034
            .:..|....::.|.::.:.| ...|..|..|...|     :|..|..:...   :..:|:   ||
 Frog  3019 FSTARNEQEARKGTISQYFT-TLHCPVCDELTQHG-----ICSKCRSQPQHVVVILNQEI---RE 3074

  Fly  1035 LEETFSRLWTECQRCQESLHEEVICSNRDCPIFYMRQKVRMDL 1077
            ||....:|...|:.|....::::.|.:.:||:.:...:|..:|
 Frog  3075 LEYKQDQLAKLCRNCTGCSNQQIQCVSLNCPVLFKLSRVSREL 3117

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DNApol-delta	NP_524099.2	PTZ00166	48..1092	CDD:240301	293/1110 (26%)
		DNA_polB_delta_exo	288..517	CDD:99820	60/259 (23%)
		POLBc_delta	564..960	CDD:99916	151/424 (36%)
		zf-C4pol	997..1070	CDD:290959	17/75 (23%)
rev3l	XP_002936975.2	PTZ00166	41..>183	CDD:240301
		DUF4683	746..1172	CDD:406222
		REV3L_RBD	1882..1904	CDD:412083
		DNA_polB_zeta_exo	2296..2532	CDD:99821	54/246 (22%)
		POLBc_zeta	2558..3006	CDD:99917	163/459 (36%)
		zf-C4pol	3042..3109	CDD:405022	17/74 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D20210at2759
OrthoFinder	1	1.000	-	-		FOG0001033
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920