DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Arl1 and Trim23

DIOPT Version :9

Sequence 1:	NP_524098.2	Gene:	Arl1 / 39745	FlyBaseID:	FBgn0000115	Length:	180	Species:	Drosophila melanogaster
Sequence 2:	XP_008758905.1	Gene:	Trim23 / 81002	RGDID:	621587	Length:	601	Species:	Rattus norvegicus

Alignment Length:	162	Identity:	82/162 - (50%)
Similarity:	112/162 - (69%)	Gaps:	1/162 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 EMRILILGLDGAGKTTILYRLQVGEVVTTIPTIGFNVEQVTYKNLKFQVWDLGGQTSIRPYWRCY 80
            |:|::.||||||||||||::|:..|.:..|||||||||.|.||||||.:||:||:..:||.|:.|
  Rat   431 EIRVVTLGLDGAGKTTILFKLKQDEFMQPIPTIGFNVETVEYKNLKFTIWDVGGKHKLRPLWKHY 495

  Fly    81 YSNTDAIIYVVDSADRDRIGISKDELLYMLREEELAGAILVVLANKQDMDGCMTVAEVHHALGLE 145
            |.||.|:::||||:.||||..:..||..:|.|:||..|:|::.|||||:.|.::|.|:...|.|.
  Rat   496 YLNTQAVVFVVDSSHRDRISEAHSELAKLLTEKELRDALLLIFANKQDVAGALSVEEITELLSLH 560

  Fly   146 NL-KNRTFQIFKTSATKGEGLDQAMDWLSNTL 176
            .| ..|::.|....|..|.||.:.:||||..|
  Rat   561 KLCCGRSWYIQGCDARSGMGLYEGLDWLSRQL 592

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arl1	NP_524098.2	Arl1	18..175	CDD:206718	80/157 (51%)
Trim23	XP_008758905.1	zf-RING_UBOX	58..100	CDD:290181
		BBOX	152..195	CDD:237988
		BBOX	200..246	CDD:197662
		BBC	253..397	CDD:128778
		ARD1	433..601	CDD:206723	81/160 (51%)
		Ras	433..592	CDD:278499	80/158 (51%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910