DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Arl1 and trim23

DIOPT Version :9

Sequence 1:	NP_524098.2	Gene:	Arl1 / 39745	FlyBaseID:	FBgn0000115	Length:	180	Species:	Drosophila melanogaster
Sequence 2:	XP_005155659.1	Gene:	trim23 / 767706	ZFINID:	ZDB-GENE-060929-804	Length:	576	Species:	Danio rerio

Alignment Length:	162	Identity:	81/162 - (50%)
Similarity:	111/162 - (68%)	Gaps:	1/162 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 EMRILILGLDGAGKTTILYRLQVGEVVTTIPTIGFNVEQVTYKNLKFQVWDLGGQTSIRPYWRCY 80
            |:|::.||||||||||||::|:..|.:..|||||||||.|.||||||.:||:||:..:||.|:.|
Zfish   406 EIRVVTLGLDGAGKTTILFKLKQDEFMQPIPTIGFNVETVEYKNLKFTIWDVGGKHKLRPLWKHY 470

  Fly    81 YSNTDAIIYVVDSADRDRIGISKDELLYMLREEELAGAILVVLANKQDMDGCMTVAEVHHALGLE 145
            |.||.|:::|:||..|||:..|..||..:|.|:||..|:|::.|||||:.|.::|.|:...|.|.
Zfish   471 YLNTQAVVFVIDSCHRDRLMESHSELAKLLTEKELRDALLLIFANKQDVPGAVSVEEMTELLSLH 535

  Fly   146 NL-KNRTFQIFKTSATKGEGLDQAMDWLSNTL 176
            .| ..|::.|....|..|.||.:.:||||..|
Zfish   536 KLCCGRSWHIQGCDARSGMGLHEGLDWLSRQL 567

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arl1	NP_524098.2	Arl1	18..175	CDD:206718	79/157 (50%)
trim23	XP_005155659.1	RING	33..76	CDD:214546
		BBOX	127..170	CDD:237988
		BBOX	175..221	CDD:197662
		iSH2_PI3K_IA_R	228..372	CDD:304922
		ARD1	408..576	CDD:206723	80/160 (50%)
		Ras	408..567	CDD:278499	79/158 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910