DRSC/TRiP Functional Genomics Resources

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Protein Alignment Arl1 and SAR1B

DIOPT Version :10

Sequence 1:NP_524098.2 Gene:Arl1 / 39745 FlyBaseID:FBgn0000115 Length:180 Species:Drosophila melanogaster
Sequence 2:NP_057187.1 Gene:SAR1B / 51128 HGNCID:10535 Length:198 Species:Homo sapiens


Alignment Length:178 Identity:51/178 - (28%)
Similarity:90/178 - (50%) Gaps:13/178 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly     8 FRGLLGSREMRILILGLDGAGKTTILYRLQVGEVVTTIPTIGFNVEQVTYKNLKFQVWDLGGQTS 72
            |.||. .:..:::.||||.|||||:|:.|:...:...:||:....|::|...:.|..:||||...
Human    18 FLGLY-KKTGKLVFLGLDNAGKTTLLHMLKDDRLGQHVPTLHPTSEELTIAGMTFTTFDLGGHVQ 81

  Fly    73 IRPYWRCYYSNTDAIIYVVDSADRDRIGISKDELLYMLREEELAGAILVVLANKQDMDGCMTVAE 137
            .|..|:.|....:.|:::||.||.:|:..||:||..::.:|.:|...:::|.||.|....::...
Human    82 ARRVWKNYLPAINGIVFLVDCADHERLLESKEELDSLMTDETIANVPILILGNKIDRPEAISEER 146

  Fly   138 VHHALG------------LENLKNRTFQIFKTSATKGEGLDQAMDWLS 173
            :....|            |:.|..|..::|..|..|.:|..:...|::
Human   147 LREMFGLYGQTTGKGSISLKELNARPLEVFMCSVLKRQGYGEGFRWMA 194

Known Domains:


Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.

GeneSequenceDomainRegion External IDIdentity
Arl1NP_524098.2 Arl1 18..175 CDD:206718 48/168 (29%)
SAR1BNP_057187.1 Sar1 3..197 CDD:206645 51/178 (29%)
STAR, SAR1-N-terminal activation recruitment. Required for the activation by PREB and subsequent recruitment to ER membrane. /evidence=ECO:0000250|UniProtKB:Q9QVY3 3..5