DRSC/TRiP Functional Genomics Resources

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Protein Alignment Arl1 and ARF1

DIOPT Version :10

Sequence 1:NP_524098.2 Gene:Arl1 / 39745 FlyBaseID:FBgn0000115 Length:180 Species:Drosophila melanogaster
Sequence 2:NP_001649.1 Gene:ARF1 / 375 HGNCID:652 Length:181 Species:Homo sapiens


Alignment Length:181 Identity:101/181 - (55%)
Similarity:137/181 - (75%) Gaps:1/181 - (0%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MGGVL-SYFRGLLGSREMRILILGLDGAGKTTILYRLQVGEVVTTIPTIGFNVEQVTYKNLKFQV 64
            ||.:. :.|:||.|.:|||||::|||.||||||||:|::||:||||||||||||.|.|||:.|.|
Human     1 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTV 65

  Fly    65 WDLGGQTSIRPYWRCYYSNTDAIIYVVDSADRDRIGISKDELLYMLREEELAGAILVVLANKQDM 129
            ||:|||..|||.||.|:.||..:|:||||.||:|:..:::||:.||.|:||..|:|:|.|||||:
Human    66 WDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLLVFANKQDL 130

  Fly   130 DGCMTVAEVHHALGLENLKNRTFQIFKTSATKGEGLDQAMDWLSNTLQSRK 180
            ...|..||:...|||.:|::|.:.|..|.||.|:||.:.:|||||.|:::|
Human   131 PNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQK 181

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Arl1NP_524098.2 Arl1 18..175 CDD:206718 90/156 (58%)
ARF1NP_001649.1 Important for the stable binding to the membranes. /evidence=ECO:0000250|UniProtKB:P84080 3..16 4/12 (33%)
ARF 5..179 CDD:128474 98/173 (57%)

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