DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Arl1 and TRIM23

DIOPT Version :9

Sequence 1:	NP_524098.2	Gene:	Arl1 / 39745	FlyBaseID:	FBgn0000115	Length:	180	Species:	Drosophila melanogaster
Sequence 2:	NP_001647.1	Gene:	TRIM23 / 373	HGNCID:	660	Length:	574	Species:	Homo sapiens

Alignment Length:	162	Identity:	82/162 - (50%)
Similarity:	112/162 - (69%)	Gaps:	1/162 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 EMRILILGLDGAGKTTILYRLQVGEVVTTIPTIGFNVEQVTYKNLKFQVWDLGGQTSIRPYWRCY 80
            |:|::.||||||||||||::|:..|.:..|||||||||.|.||||||.:||:||:..:||.|:.|
Human   404 EIRVVTLGLDGAGKTTILFKLKQDEFMQPIPTIGFNVETVEYKNLKFTIWDVGGKHKLRPLWKHY 468

  Fly    81 YSNTDAIIYVVDSADRDRIGISKDELLYMLREEELAGAILVVLANKQDMDGCMTVAEVHHALGLE 145
            |.||.|:::||||:.||||..:..||..:|.|:||..|:|::.|||||:.|.::|.|:...|.|.
Human   469 YLNTQAVVFVVDSSHRDRISEAHSELAKLLTEKELRDALLLIFANKQDVAGALSVEEITELLSLH 533

  Fly   146 NL-KNRTFQIFKTSATKGEGLDQAMDWLSNTL 176
            .| ..|::.|....|..|.||.:.:||||..|
Human   534 KLCCGRSWYIQGCDARSGMGLYEGLDWLSRQL 565

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arl1	NP_524098.2	Arl1	18..175	CDD:206718	80/157 (51%)
TRIM23	NP_001647.1	mRING-HC-C3HC3D_TRIM23_C-IX	28..77	CDD:319559
		Bbox2_TRIM23_C-IX_rpt1	123..172	CDD:380831
		Bbox2_TRIM23_C-IX_rpt2	174..223	CDD:380832
		BBC	226..370	CDD:128778
		ARF-like	390..574		82/162 (51%)
		ARD1	406..574	CDD:206723	81/160 (51%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910