Protein Alignment brm and Smarca5

DIOPT Version :10

• Sequence 1: NP_001261906.1
• Gene: brm / 39744
• FlyBaseID: FBgn0000212
• Length: 1658
• Species: Drosophila melanogaster
• Sequence 2: NP_444354.2
• Gene: Smarca5 / 93762
• MGIID: 1935129
• Length: 1051
• Species: Mus musculus
• Alignment Length: 928
• Identity: 305/928 - (32%)
• Similarity: 464/928 - (50%)
• Gaps: 160/928 - (17%)

  Fly   680 LNMHPGWDWI-DDEEDSCGSNDDHKPKVEEQPTATEDATDKAQATGNDEDAKDLITKAKVEDDEY 743
            |.|.||...: .||:.:..|..|::.:..||.                            ||:|.
Mouse   117 LKMKPGRPRVKKDEKQNLLSVGDYRHRRTEQE----------------------------EDEEL 153

  Fly   744 RTEEQTYYSIAHTIHEKVVEQASIMVNGTLKEYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQT 808
            .||.    |.|..:..:..:..|.:..|.|::||::||.||:|||.|.:|||||||||||||:||
Mouse   154 LTES----SKATNVCTRFEDSPSYVKWGKLRDYQVRGLNWLISLYENGINGILADEMGLGKTLQT 214

  Fly   809 ISLVTYLMDRKKVMGPYLIIVPLSTLPNWVLEFEKWAPAVGVVSYKGSPQGR-RLLQNQMRATKF 872
            |||:.|:...:.:.||::::||.|||.||:.||:||.|.:..|...|..:.| ..:::.:...::
Mouse   215 ISLLGYMKHYRNIPGPHMVLVPKSTLHNWMSEFKKWVPTLRSVCLIGDKEQRAAFVRDVLLPGEW 279

  Fly   873 NVLLTTYEYVIKDKAVLAKIQWKYMIIDEGHRMKNHHCKLTQVLNTHYIAPYRLLLTGTPLQNKL 937
            :|.:|:||.:||:|:|..|..|:|::|||.||:||...||::::. .:....|||||||||||.|
Mouse   280 DVCVTSYEMLIKEKSVFKKFNWRYLVIDEAHRIKNEKSKLSEIVR-EFKTTNRLLLTGTPLQNNL 343

  Fly   938 PELWALLNFLLPSIFKSCSTFEQWFNAPFATTGEKVELNEEETILIIRRLHKVLRPFLLRRLKKE 1002
            .|||:|||||||.:|.|...|:.||:.......:|          ::.|||.|||||||||:|.:
Mouse   344 HELWSLLNFLLPDVFNSADDFDSWFDTNNCLGDQK----------LVERLHMVLRPFLLRRIKAD 398

  Fly  1003 VEHQLPDKVEYIIKCDMSALQRVLYKHMQSKGVLLTDGSEKGKHGKGGAKALMNTIVQLRKLCNH 1067
            ||..||.|.|..|...:|.:||..|..:..|.:.:.:.:     ||.....|:|.::||||.|||
Mouse   399 VEKSLPPKKEVKIYVGLSKMQREWYTRILMKDIDILNSA-----GKMDKMRLLNILMQLRKCCNH 458

  Fly  1068 PFMFQHIEEKYCDHTGGHGVVSGP----DLYRV--SGKFELLDRILPKLKATNHRVLLFCQMTQC 1126
            |::|.             |...||    |::.|  |||..:||::|||||....|||:|.|||:.
Mouse   459 PYLFD-------------GAEPGPPYTTDMHLVTNSGKMVVLDKLLPKLKEQGSRVLIFSQMTRV 510

  Fly  1127 MTIIEDYLGWRQFGYLRLDGTTKAEDRGELLRKFNAKGSDVFVFLLSTRAGGLGLNLQTADTVVI 1191
            :.|:|||..||.:.|.||||.|..::|.:.:..:|...|..|||:|||||||||:||.|||.|::
Mouse   511 LDILEDYCMWRNYEYCRLDGQTPHDERQDSINAYNEPNSTKFVFMLSTRAGGLGINLATADVVIL 575

  Fly  1192 FDSDWNPHQDLQAQDRAHRIGQRNEVRVLRLMTVNSVEERILAAARYKLNMDEKVIQAG-MFDQK 1255
            :||||||..||||.||||||||...|||.|.:|.|:|||||:..|..||.:|..|||.| :.||.
Mouse   576 YDSDWNPQVDLQAMDRAHRIGQTKTVRVFRFITDNTVEERIVERAEMKLRLDSIVIQQGRLVDQN 640

  Fly  1256 STGSERQQFLQTILHQDDNE-EEEENEVPDDEMINMMIARSEEEIEIFKRMDAERKKEDEEIHPG 1319
            .....:.:.||.|.|...:. ..:|:|:.|:::..::...:::..|:.:::..
Mouse   641 LNKIGKDEMLQMIRHGATHVFASKESEITDEDIDGILERGAKKTAEMNEKLSK------------ 693

  Fly  1320 RERLIDESELPDWLTKDDDEVERFHYQYDEDTILGRGSRQRKEVDYTDSLTEKEWLK-------- 1376
                :.||.|.::....:..|..|.         |...|:::::.:|      ||::
Mouse   694 ----MGESSLRNFTMDTESSVYNFE---------GEDYREKQKIAFT------EWIEPPKRERKA 739

  Fly  1377 --AIDDGAEFDEEEEEDDSKRKRRKRKNRKEESDD------------DSLILKRRRR-------- 1419
              |:|  |.|.|.....:.|..:..|..::....|            :..||..|:.
Mouse   740 NYAVD--AYFREALRVSEPKAPKAPRPPKQPNVQDFQFFPPRLFELLEKEILYYRKTIGYKVPRS 802

  Fly  1420 ---QNLDKRSKKQMHKIMSAVIKHNQD----GRTLSEPFMKLPSRQRLPDYYEIIKRPV-----D 1472
               .|..:..|::..||..|...::::    .:.|::.|.....|    |:.:.||...     |
Mouse   803 PDLPNAAQAQKEEQLKIDEAEPLNDEELEEKEKLLTQGFTNWNKR----DFNQFIKANEKWGRDD 863

  Fly  1473 IKKILQRIEDCKYADLNELEKDFMQLCQN--------AQIYNEEASLIYLDSIALQKVFVGARQR 1529
            |:.|.:.:|.....::.|....|.:.|..        |||...||.:  ...|:::|.......|
Mouse   864 IENIAREVEGKTPEEVIEYSAVFWERCNELQDIEKIMAQIERGEARI--QRRISIKKALDTKIGR 926

  Fly  1530 ITAAADAAAVAAGDNTGE 1547
            ..|......::.|.|.|:
Mouse   927 YKAPFHQLRISYGTNKGK 944

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
brm	NP_001261906.1	QLQ	173..202	CDD:462622
		Pro-rich	<247..401	CDD:464580
		PTZ00121	<477..651	CDD:173412
		HSA	501..573	CDD:214727
		BRK	650..691	CDD:462196	4/11 (36%)
		PLN03142	739..>1368	CDD:215601	252/637 (40%)
		Bromo_SNF2L2	1425..1530	CDD:99947	24/121 (20%)
Smarca5	NP_444354.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..81
		PLN03142	68..1011	CDD:215601	305/928 (33%)
		DEAH box	307..310		2/2 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1014..1051