Protein Alignment brm and RAD54

DIOPT Version :10

• Sequence 1: NP_001261906.1
• Gene: brm / 39744
• FlyBaseID: FBgn0000212
• Length: 1658
• Species: Drosophila melanogaster
• Sequence 2: NP_011352.1
• Gene: RAD54 / 852713
• SGDID: S000003131
• Length: 898
• Species: Saccharomyces cerevisiae
• Alignment Length: 869
• Identity: 215/869 - (24%)
• Similarity: 367/869 - (42%)
• Gaps: 196/869 - (22%)

  Fly   507 RKRRQKHLEFLAAVLQHGKDLR--EFHRNNK----AQLARMNKAVMNHHANAEREQKKEQERIE- 564
            |||.       |.|...|.|:.  |...|::    :||.:..|..:    :|:| ..|:..|:.
Yeast    70 RKRS-------ATVCYSGLDINADEAEYNSQDISFSQLTKRRKDAL----SAQR-LAKDPTRLSH 122

  Fly   565 -KERMRRLMAEDEEGY-------------RKLIDQKKDKRLAFLLSQTDEYISNL------TQMV 609
             :..:||......:||             :|:..:.:.     |...|||:...|      .:|:
Yeast   123 IQYTLRRSFTVPIKGYVQRHSLPLTLGMKKKITPEPRP-----LHDPTDEFAIVLYDPSVDGEMI 182

  Fly   610 KQHKDDQMKKKEEEGKRLIQFKKELLMSGEYIGIDEGSIVADMRVHVVEQCTGKKLTGDDAPMLK 674
            ..  |..|..||||.|::|:..:|                       .:....:|.:.::.|..:
Yeast   183 VH--DTSMDNKEEESKKMIKSTQE-----------------------KDNINKEKNSQEERPTQR 222

  Fly   675 HLHRWLNMHPGW-----------DWIDDEEDSCGSNDDHKPKVEEQPTATEDATDKAQATGNDED 728
                 :..||..           :.:.|.|:|.    ::|.|....|...:....|.......|.
Yeast   223 -----IGRHPALMTNGVRNKPLRELLGDSENSA----ENKKKFASVPVVIDPKLAKILRPHQVEG 278

  Fly   729 AK-------DLITKAKVEDDEYRTEEQTYYSIAHTIHEKVVEQASIMVNGTLKEYQIKGLEWLVS 786
            .:       .|:.|..:|.:.:.|..:                      ..||..: |.|.....
Yeast   279 VRFLYRCVTGLVMKDYLEAEAFNTSSE----------------------DPLKSDE-KALTESQK 320

  Fly   787 LYNNNLNG---ILADEMGLGKTIQTISLVTYLMDR----KKVMGPYLIIVPLSTLPNWVLEFEKW 844
            ...||...   |:|||||||||:|.|:|:..|:.:    |:::...:|:.|.|.:.||..|..||
Yeast   321 TEQNNRGAYGCIMADEMGLGKTLQCIALMWTLLRQGPQGKRLIDKCIIVCPSSLVNNWANELIKW 385

  Fly   845 -----APAVGVVSYKGS-----------------PQGRRLLQNQMRATKFNVLLTTYEYVIKDKA 887
                 ...:.|...|.|                 .|||.:::        .||:.:||.:.::..
Yeast   386 LGPNTLTPLAVDGKKSSMGGGNTTVSQAIHAWAQAQGRNIVK--------PVLIISYETLRRNVD 442

  Fly   888 VLAKIQWKYMIIDEGHRMKNHHCKLTQVLNTHYIAPYRLLLTGTPLQNKLPELWALLNFLLPSIF 952
            .|.......|:.|||||:||.. .||.........|.|::|:|||:||.|.|.:|||:|..|.:.
Yeast   443 QLKNCNVGLMLADEGHRLKNGD-SLTFTALDSISCPRRVILSGTPIQNDLSEYFALLSFSNPGLL 506

  Fly   953 KSCSTFEQWFNAPFA------TTGEKVELNEEETILIIRRLHKVLRPFLLRRLKKEVEHQLPDKV 1011
            .|.:.|.:.|..|..      .|.:::...|.:    :::|..::..|::||....:...||.|.
Yeast   507 GSRAEFRKNFENPILRGRDADATDKEITKGEAQ----LQKLSTIVSKFIIRRTNDILAKYLPCKY 567

  Fly  1012 EYIIKCDMSALQRVLY-KHMQSKGVLLTDGSEKGKHGKGGAKALMNTIVQLRKLCNHPFMFQHIE 1075
            |::|..::..||..|| |.::|:.|      :|...|.||::.| ..|..|:||||||.:. :.|
Yeast   568 EHVIFVNLKPLQNELYNKLIKSREV------KKVVKGVGGSQPL-RAIGILKKLCNHPNLL-NFE 624

  Fly  1076 EKYCDHTGGHGVVSGPDLYRVSG------------KFELLDRILPKLKA-TNHRVLLFCQMTQCM 1127
            :::.|...    :..||.|.:.|            ||.:|:|.|.|:|. ::.:::|....||.:
Yeast   625 DEFDDEDD----LELPDDYNMPGSKARDVQTKYSAKFSILERFLHKIKTESDDKIVLISNYTQTL 685

  Fly  1128 TIIEDYLGWRQFGYLRLDGTTKAEDRGELLRKFNAKGSDVFVFLLSTRAGGLGLNLQTADTVVIF 1192
            .:||....::.:..:|||||.....|.:|:.:||......|:||||::|||.|:||..|:.:::.
Yeast   686 DLIEKMCRYKHYSAVRLDGTMSINKRQKLVDRFNDPEGQEFIFLLSSKAGGCGINLIGANRLILM 750

  Fly  1193 DSDWNPHQDLQAQDRAHRIGQRNEVRVLRLMTVNSVEERILAAARYKLNMDEKVIQAGMFDQKST 1257
            |.||||..|.||..|..|.||:.:..:.|.::..::||:|......|:::...|:.|....::..
Yeast   751 DPDWNPAADQQALARVWRDGQKKDCFIYRFISTGTIEEKIFQRQSMKMSLSSCVVDAKEDVERLF 815

  Fly  1258 GSERQQFLQTILHQDDNEEEEENE 1281
            .|:.   |:.:..:::|...|.:|
Yeast   816 SSDN---LRQLFQKNENTICETHE 836

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
brm	NP_001261906.1	QLQ	173..202	CDD:462622
		Pro-rich	<247..401	CDD:464580
		PTZ00121	<477..651	CDD:173412	36/170 (21%)
		HSA	501..573	CDD:214727	18/73 (25%)
		BRK	650..691	CDD:462196	4/51 (8%)
		PLN03142	739..>1368	CDD:215601	165/592 (28%)
		Bromo_SNF2L2	1425..1530	CDD:99947
RAD54	NP_011352.1	Rad54_N	29..246	CDD:430137	40/222 (18%)
		HepA	<271..806	CDD:440319	162/582 (28%)
		DEXHc_RAD54A	271..554	CDD:350825	78/318 (25%)