Protein Alignment brm and PKR2

DIOPT Version :10

• Sequence 1: NP_001261906.1
• Gene: brm / 39744
• FlyBaseID: FBgn0000212
• Length: 1658
• Species: Drosophila melanogaster
• Sequence 2: NP_194918.2
• Gene: PKR2 / 829320
• AraportID: AT4G31900
• Length: 1202
• Species: Arabidopsis thaliana
• Alignment Length: 906
• Identity: 279/906 - (30%)
• Similarity: 451/906 - (49%)
• Gaps: 142/906 - (15%)

  Fly   677 HRWLNMHPGWDWIDDEEDSCGSNDD---HKPKVEE---QPTATEDATDKAQATGNDEDAKDLITK 735
            |.::.:.|.|..: |...:|...||   :..|.:|   :.:..|..:|.:......:..||:.:.
plant   132 HEFIAIRPEWKTV-DRIIACREGDDGEEYLVKYKELSYRNSYWESESDISDFQNEIQRFKDINSS 195

  Fly   736 AK----VEDDEYRTEEQTYYSIAHTIHEKVVEQASIMVNGTLKEYQIKGLEWLVSLYNNNLNGIL 796
            ::    ||::..|.|.:.:            :.....:.|||..||::||.:|...::...|.||
plant   196 SRRDKYVENERNREEFKQF------------DLTPEFLTGTLHTYQLEGLNFLRYSWSKKTNVIL 248

  Fly   797 ADEMGLGKTIQTISLVTYLMDRKKVMGPYLIIVPLSTLPNWVLEFEKWAPAVGVVSYKGSPQGRR 861
            |||||||||||:|:.:..|.:..  :.|:|::.||||:.||..||..|||.:.||.|.|..:.|.
plant   249 ADEMGLGKTIQSIAFLASLFEEN--LSPHLVVAPLSTIRNWEREFATWAPHMNVVMYTGDSEARD 311

  Fly   862 LLQ------NQMRATKFNVLLTTYEYVIKDKAVLAKIQWKYMIIDEGHRMKNHHCKLTQVLNTHY 920
            ::.      ::.|.:||:|||||||.|....:||:.|:|..||||||||:||...||...| :.:
plant   312 VIWEHEFYFSEGRKSKFDVLLTTYEMVHPGISVLSPIKWTCMIIDEGHRLKNQKSKLYSSL-SQF 375

  Fly   921 IAPYRLLLTGTPLQNKLPELWALLNFLLPSIFKSCSTFEQWFNAPFATTGEKVELNEEETILIIR 985
            .:.:.:|||||||||.|.||:||::||....|.|...|:              ::|:||.   |.
plant   376 TSKHIVLLTGTPLQNNLNELFALMHFLDADKFGSLEKFQ--------------DINKEEQ---IS 423

  Fly   986 RLHKVLRPFLLRRLKKEV-EHQLPDKVEYIIKCDMSALQRVLYKHMQSKGV-LLTDGSEKGKHGK 1048
            |||::|.|.|||||||:| :.::|.|.|.|::.|||:.|:.:||.:.:... :||.        |
plant   424 RLHQMLAPHLLRRLKKDVLKDKVPPKKELILRVDMSSQQKEVYKAVITNNYQVLTK--------K 480

  Fly  1049 GGAKALMNTIVQLRKLCNHPFMFQHIEEKYCDHTGGHGVVSGPDLYRVSGKFELLDRILPKLKAT 1113
            ..|| :.|.:::||::|:||::....|.::.|.....     ..|...|||.:|||:::.|||..
plant   481 RDAK-ISNVLMKLRQVCSHPYLLPDFEPRFEDANEAF-----TKLLEASGKLQLLDKMMVKLKEQ 539

  Fly  1114 NHRVLLFCQMTQCMTIIEDYLGWRQFGYLRLDGTTKAEDRGELLRKFNAKGSDVFVFLLSTRAGG 1178
            .||||::.|....:.::|||..::.:.|.|:||.....:|...:.:|||:.|:.|.|||||||||
plant   540 GHRVLIYTQFQHTLYLLEDYFTFKNWNYERIDGKISGPERQVRIDRFNAENSNRFCFLLSTRAGG 604

  Fly  1179 LGLNLQTADTVVIFDSDWNPHQDLQAQDRAHRIGQRNEVRVLRLMTVNSVEERILAAARYKLNMD 1243
            :|:||.|||||:|:|||||||.||||..|.||:||.|:|.:.||:...:||||::...:.|:.::
plant   605 IGINLATADTVIIYDSDWNPHADLQAMARVHRLGQTNKVMIYRLIHKGTVEERMMEITKNKMLLE 669

  Fly  1244 EKVIQAGMFDQKSTGSER--QQFLQTILHQDDNE--EEEENEVP-------DDEMINMMIARS-- 1295
            ..|:          |.:.  |..|..|:.....|  .||.:|..       ||..|..::.|:
plant   670 HLVV----------GKQHLCQDELDDIIKYGSKELFSEENDEAGRSGKIHYDDAAIEQLLDRNHV 724

  Fly  1296 ---------EEEIEI--------FKRMDAERKK---EDEEIHPGRERLIDESELPDW--LTKDDD 1338
                     |||.:.        |:.:|.|.:.   |:.:.......:.:......|  |.||..
plant   725 DAVEVSLDDEEETDFLKNFKVASFEYVDDENEAAALEEAQAIENNSSVRNADRTSHWKDLLKDKY 789

  Fly  1339 EVERFHYQYDEDTILGRGSRQRKEVDYT-------DSLTEKEWLKAIDDGAEFDEEEEEDDSKRK 1396
            ||:    |.:|.:.||:..|..|:|.|.       :.::::|....:||.....:||||.|....
plant   790 EVQ----QAEELSALGKRKRNGKQVMYAEDDLDGLEEISDEEDEYCLDDLKVTSDEEEEADEPEA 850

  Fly  1397 RRKRKNRKEESDDDSLILKRRRRQNLDKRSKKQMHKIMSAVIKHNQDGRTLSEPFMKLPSRQRLP 1461
            .|:||.|.....     .::|.|.|.::....:.......|:..|:..|.:   |::...|....
plant   851 ARQRKPRTVTRP-----YRKRARDNSEEIPLMEGEGRYLMVLGFNETERDI---FLRTFKRYGAG 907

  Fly  1462 DYYEIIKRPVDIKKILQRIEDCKYADLNELEKDFMQ-----LCQNAQIYNEEASLIYLDSI 1517
            ::        |.|:.:..:....|.::|:....|::     ...|:..:....:::|.|.:
plant   908 NF--------DWKEFVNPLYMKTYDEINKYGILFLKHIAENPTDNSTNFKVITAMVYADGV 960

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
brm	NP_001261906.1	QLQ	173..202	CDD:462622
		Pro-rich	<247..401	CDD:464580
		PTZ00121	<477..651	CDD:173412
		HSA	501..573	CDD:214727
		BRK	650..691	CDD:462196	3/13 (23%)
		PLN03142	739..>1368	CDD:215601	237/678 (35%)
		Bromo_SNF2L2	1425..1530	CDD:99947	13/98 (13%)
PKR2	NP_194918.2	CD1_tandem	43..118	CDD:349307
		CD2_tandem	140..191	CDD:349306	9/51 (18%)
		HepA	<202..674	CDD:440319	205/527 (39%)
		DUF1087	<774..816	CDD:461922	14/45 (31%)
		CHDII_SANT-like	856..999	CDD:461920	17/121 (14%)