|
Fly 323 EPHQHQLPNGGKPLSMGPSGGQPLIPSSPMQPQVRGTLPGMPPGSQVPQPGGGPQRQVPPAGMPM 387
||.:.:...|.|.....|...:. |..|.:|: .::.|:....|:......|:..
Mouse 100 EPGEQEGTKGSKDREPKPKRKRE--PKEPKEPR----------RAKEPKRAKEPKETKQKDGVKK 152
Fly 388 PKPNRITTVAKPVGLDPITLLQERENRIAARISLRMQELQRLPATMSEDLRLQAAIELRALRVLN 452
|:.:|..:..| :.:|.|.......| |.|: :|:.|.....|..
Mouse 153 PRKHREASGTK----------EGKEKRSCTDYGSR---------TKSK----KASREQGPTPVER 194
Fly 453 FQRQLRMEFVQCTRRDTTLETALNIKLYKRTKRQGLRE-ARATEKLEKQQKLEAERKRRQKHLEF 516
.::..| :.:||:| :::|........|:. ...:|..:.|::....:.:|:|:.|.
Mouse 195 KKKGKR-------KNETTVE---SLELDHSLPNPSLQSPEEPSESADSQKRRSGRQVKRRKYNED 249
Fly 517 L--AAVLQHGKDLREFHRNNKAQLARMNKAVMNHHANAEREQKKEQERIEKERMRRLMAEDEEG- 578
| ..|...|:.:........:.|:....| ..||...:.:...|||....:.:.|...|
Mouse 250 LDFKVVDDDGETIAVLGAGRTSALSASTLA-----WQAEEPPEDDANIIEKILASKTVQEVHPGE 309
Fly 579 -----------YRK----------LIDQKKDKRLAFLLSQTDEYISNLTQMVKQHKDDQMKKKEE 622
||. :.:.:||.|:| |.:| :.:.|:.
Mouse 310 PPFDLELFYVKYRNFSYLHCKWATMEELEKDPRIA--------------QKIK-----RFRNKQA 355
Fly 623 EGKRLIQFKKELLMSGEYIGIDEGSIVADMRVHVVEQCTGKKLTGDDAPMLKHLHRWLNM---HP 684
:.|.:.....|.|.:.:||.||....|| |..:..||:::| .:|.:|.:: ..
Mouse 356 QMKHIFTEPDEDLFNPDYIEIDRILEVA----HTKDAETGEEVT-------HYLVKWCSLPYEES 409
Fly 685 GWDWIDDEEDSCGSNDDHK----PKVEEQPTATEDATDKAQATGNDEDAKDLITKAKVEDDEYRT 745
.|: ::::.|.....:... |:|:.......||..|.:.: .|||.
Mouse 410 TWE-LEEDVDPAKVKEFESLQILPEVKHVERPASDAWQKLETS-----------------REYRN 456
Fly 746 EEQTYYSIAHTIHEKVVEQASIMVNGTLKEYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTIS 810
..: |:|||::|:.||:..:.|..|.|||||||||||||:|:
Mouse 457 SNR------------------------LREYQLEGMNWLLFNWYNRKNCILADEMGLGKTIQSIA 497
Fly 811 LVTYLMDRKKVMGPYLIIVPLSTLPNWVLEFEKWAPAVGVVSYKGSPQGRRLLQ----------- 864
.::.:..| .:.||:|||.||||:.||..||..|.....:| |.||...|:::|
Mouse 498 FLSEIFVR-GIHGPFLIIAPLSTITNWEREFRTWTEMNAIV-YHGSQISRQMIQQYEMVYRDAQG 560
Fly 865 NQMRAT-KFNVLLTTYEYVIKDKAVLAKIQWKYMIIDEGHRMKNHHCKLTQVLNTHYIAPYRLLL 928
|.:... ||:|::||:|.::.|...|.||.|..:||||.||:||.:|||.:.|....: .:::||
Mouse 561 NPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAHRLKNRNCKLLEGLKLMAL-EHKVLL 624
Fly 929 TGTPLQNKLPELWALLNFLLPSIFKSCSTFEQWFNAPFATTGEKVELNEEETILIIRRLHKVLRP 993
|||||||.:.||::|||||.||.|.|.:.|.:.|. :|..||. :::|..:|:|
Mouse 625 TGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFG----------DLKTEEQ---VKKLQSILKP 676
Fly 994 FLLRRLKKEVEHQLPDKVEYIIKCDMSALQRVLYKHMQSKGV-LLTDGSEKGKHGKGGAKALMNT 1057
.:|||||.:||..|..|.|.||:.:::.:|:..|:.:..|.. .||.|: .:|.... |:||
Mouse 677 MMLRRLKDDVEKNLAPKQETIIEVELTNIQKKYYRAILEKNFSFLTKGA--NQHNMPN---LINT 736
Fly 1058 IVQLRKLCNHPFMFQHIEEKYCD-----HTGGHGVVSGPDLYRVSGKFELLDRILPKLKATNHRV 1117
:::|||.||||::....|||..: |:..........:.:.:||..|:|::||||.|..|:|
Mouse 737 MMELRKCCNHPYLINGAEEKILEDFRKAHSSEASDFQLQAMIQAAGKLVLIDKLLPKLIAGGHKV 801
Fly 1118 LLFCQMTQCMTIIEDYLGWRQFGYLRLDGTTKAEDRGELLRKFNAKGSDVFVFLLSTRAGGLGLN 1182
|:|.||.:|:.|:||||..|::.|.|:||..:...|...:.:|....||.|||||.|||||||:|
Mouse 802 LIFSQMVRCLDILEDYLIQRRYTYERIDGRVRGNLRQAAIDRFCKPDSDRFVFLLCTRAGGLGIN 866
Fly 1183 LQTADTVVIFDSDWNPHQDLQAQDRAHRIGQRNEVRVLRLMTVNSVEERILAAARYKLNMDEKVI 1247
|..|||.:||||||||..|||||.|.|||||...|:|.||:|.||.|..:...|..||.:|:.::
Mouse 867 LTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAIL 931
Fly 1248 QAGMFDQKSTGSERQQF----LQTILHQDD----NEEEEENEVPDDEMINMMIARSEEEIEI--- 1301
|. .::|.:.:..||. ::.:|.:.. .:||:|.....:|.|:.::.|....|.|
Mouse 932 QD--INRKGSTNGVQQLSKMEVEDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSE 994
Fly 1302 ---------------------------------FKRMDAERKKEDEEIHPGRERL---------I 1324
...:|.|...|.|.:...|.|: .
Mouse 995 GKGSTFAKASFVASGNRTDISLDDPNFWQKWAKIAELDTEANNEKESLVIDRPRVRKQTKHYNSF 1059
Fly 1325 DESELPDWLTKDDDEVERFHYQYDEDTILGRGSRQRKEVDYTDSLTEKE---------------W 1374
:|.||.::...|.|..| |.:|.|:..|........| |
Mouse 1060 EEDELMEFSELDSDSDE-------------RPTRSRRLSDRARRYLRAECFRVEKNLLIFGWGRW 1111
Fly 1375 LKAIDDGA---EFDEEEEE---------------DDSKRKR------------------------ 1397
...:..|. ..:|::.| .|.|.|.
Mouse 1112 KDILTHGRFKWPLNEKDMEMICRALLVYCVKHYKGDEKIKSFIWELITPSKDGQVQTLQNHSGLS 1176
Fly 1398 ----RKRKNRKEESDDDSLILKRRRRQNLD-----------------KRSKKQMHKIMSAV---- 1437
|.||.:|.: :.|:|...: |.| |..|:..:|::..|
Mouse 1177 APVPRGRKGKKTK---NQLLLPELK--NADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLY 1236
Fly 1438 -IKHNQDGRTLSEPFMKLPSRQ---RLP--DYYEIIKRPVD------IKKILQRIEDCKYADLNE 1490
:|....|....:.|...|:|: .|| ||.|| ||| .|.:|..:....|...|.
Mouse 1237 YLKAEILGEAADKAFEGTPARELDVLLPDIDYVEI---PVDWWDAEADKSLLIGVFKHGYERYNA 1298
Fly 1491 LEKDFMQLCQNAQIYNEEASLIYLDSIAL-QKVFVGARQRITAAADAAAVAAGDNTGEAHGNGGS 1554
:..| .:|.:|:.:.: .:..:.|.|.:| |.|.:....|..
Mouse 1299 MRAD--------------PALCFLEKVGMPDEKSLSAEQGVT-----------DGTSDIPERGNI 1338
Fly 1555 DNSDNDDD-------------DGGD--------------DGSDDEEIATTSAAAVKMKL------ 1586
|..|:.:| ||.| ||||.::.....::|:..:|
Mouse 1339 DKEDSAEDKLDGLQKQTASPSDGSDGIFGEKKDDSQAAQDGSDPDKSPWPVSSALTARLRRLVTI 1403
Fly 1587 --KLNKSLASAPAT--PTQSSSNVSSGA-ATTSKKQTRRKRSQKKYTISDDDDDDMDXLPLGVIF 1646
:.|:.....|.. |......|.... ..||:.....|.:||::|..:..|........||::
Mouse 1404 YQRCNRKELCRPEILGPGNQGYWVQEEVFRRTSEMDLINKEAQKRWTRREQADFYRTVSSFGVVY 1468
Fly 1647 1646
Mouse 1469 1468
| 
