Protein Alignment brm and smarcad1a

DIOPT Version :10

• Sequence 1: NP_001261906.1
• Gene: brm / 39744
• FlyBaseID: FBgn0000212
• Length: 1658
• Species: Drosophila melanogaster
• Sequence 2: NP_001018610.2
• Gene: smarcad1a / 557875
• ZFINID: ZDB-GENE-050522-499
• Length: 972
• Species: Danio rerio
• Alignment Length: 976
• Identity: 269/976 - (27%)
• Similarity: 453/976 - (46%)
• Gaps: 204/976 - (20%)

  Fly   425 ELQRLPATMSEDLR--LQAAIELRALRVLN-FQRQLRMEFVQCTRRDTTLETALN--IKLYKRTK 484
            |:.|:....:.||:  :...:|.:.:::|. |.::.:.:.::.....:||:.|:.  :.:|....
Zfish    63 EVVRMGKDSASDLQQHINKDMEDKIIKLLEIFPQKSKKDLLEVIENTSTLDGAVAHCLMIYGDED 127

  Fly   485 RQGLREARATEKLEKQQKLEAERKRRQKHLEFLAAVLQHGKDLREFHRNNKAQLARMNKAVMNHH 549
            ..|.::.......:.|.|    :||:.:..:...:..:..:|......:.:.|.|.:.|.
Zfish   128 SGGRKDKGGRSDDDDQPK----KKRKIQRSDSSESEDEDSEDEESEEPSREKQEALLKKL----- 183

  Fly   550 ANAEREQKKEQERIEKERMRRLMAEDEEGYRKLIDQKKDKRLAFLLSQTDEYISNLTQMVKQHKD 614
                   |::...||||.:|.::.|.:..|...:..      ..:.|.||      |...:..|.
Zfish   184 -------KRKLPDIEKEVLRDILKEHDWDYENALGS------LLVFSSTD------TSSPEDQKS 229

  Fly   615 DQMKK---KEEEGKRLIQ-------FKKELLMSGEYIGIDEGSIVADMRVH--VVEQCTG----- 662
            .|..|   .:|:..::.|       ..:.|..:..:  :.|.|.::.::..  .:.:.|.
Zfish   230 KQKSKSSHSKEKTDKITQRPSGSSSLSRWLTAASSH--VPEVSSMSALKTQKSALSKSTSKNSSF 292

  Fly   663 KKLTGDDAPMLKHLHRWLNMHPGWDWIDDEEDSCGSNDDHKPKVEEQPTAT---------EDAT- 717
            |:..||:.|:     ..::.....|.||.:.||  .:||...:.|:..:.|         :||:
Zfish   293 KRKRGDEMPL-----NDVSASEDEDEIDSDVDS--MSDDQDSEDEDSISGTLQDKIIQFLQDASL 350

  Fly   718 -----------DKAQAT------GNDEDAK-----------DLITKAKVEDDEYRTEEQTYYSI- 753
                       .|||..      ...:|.|           ||:...||    ...|.|....:
Zfish   351 DELALISGCSIKKAQKIISLRPFNTWKDVKEQFFKDNGLSIDLVHGCKV----VLKERQVVLDLM 411

  Fly   754 --AHTIHEKVVEQASIMVN---GTLKE------------YQIKGLEWLVSLYNNNLNGILADEMG 801
              ...|.:|:.:..:.::.   |::|:            ||:.||:||:.|:.:.|:||||||||
Zfish   412 GRCEKIAQKMTKDVTQVIEAGMGSIKQPKVLNSNLKLQAYQLIGLKWLILLHQHKLSGILADEMG 476

  Fly   802 LGKTIQTISLVTYLMDRKKVMGPYLIIVPLSTLPNWVLEFEKWAPAVGVVSYKGSPQGRRLLQNQ 866
            ||||||.|:.:.:|.: |.:.||:||.||.|||.|||.|...|.|::.|:.|.||.:.|:.|:..
Zfish   477 LGKTIQAIAFLAHLYE-KGIKGPHLITVPSSTLDNWVRELGLWCPSLKVLIYYGSVEDRKYLRQD 540

  Fly   867 MRA--TKFNVLLTTYEYVI---KDKAVLAKIQWKYMIIDEGHRMKNHHCKLTQVLNTHYI---AP 923
            :..  ..||::::||...|   .|:::..|::.||.:.||||.:||    :..:...|.:   |.
Zfish   541 ILTGLIDFNIIVSTYNLTIGNDHDRSLFRKLKLKYAVFDEGHMLKN----MNSLRYRHLMTINAE 601

  Fly   924 YRLLLTGTPLQNKLPELWALLNFLLPSIFKSCSTFEQWFNAPFATTGEKVELNEEETILIIRRLH 988
            :|||||||||||.|.||.:||||::||:|.| ||.:  .:..|:|...:.|.:..:..:...||
Zfish   602 HRLLLTGTPLQNNLLELMSLLNFIMPSMFSS-STSQ--ISKMFSTRSSEEESSFHKDRIAQARL- 662

  Fly   989 KVLRPFLLRRLKKEVEHQLPDKVEYIIKCDMSALQR----VLYKHMQSKGVLLTDGSEKGKHGKG 1049
             :::||:|||:|.||..:||.|:|.|..|.||..|.    :|:|.::             |...|
Zfish   663 -IMKPFILRRVKSEVLKELPPKMEKIEMCPMSDAQHKLYDILFKRLK-------------KTPNG 713

  Fly  1050 GAKALMNTIVQLRKLCNHPFMFQH---------------------------IEE----------- 1076
            ..:.|.|.::||||:.|||.:.:.                           |:|
Zfish   714 DKRELCNVMMQLRKMANHPLLHRQYYTSDKLAAMSKAMLKEPTHYDADPALIQEDMEVMSDFELH 778

  Fly  1077 KYCDHTGGHGVVSGPDLYRV----SGKFELLDRILPKLKATNHRVLLFCQMTQCMTIIEDYLGWR 1137
            ..|..   :..:||..|.:.    ||||.||.:.|.|||....||:||.|.|..:.|:|..|...
Zfish   779 NLCRE---YSSISGFQLEKALILDSGKFALLTKTLAKLKEKGDRVVLFSQFTMMLDIVEILLKHL 840

  Fly  1138 QFGYLRLDGTTKAEDRGELLRKFNAKGSDVFVFLLSTRAGGLGLNLQTADTVVIFDSDWNPHQDL 1202
            ...|:||||:|...:|..|:.|:|. ..::|||||||||||.|:||.:|:||::.|.|.||..|.
Zfish   841 DHQYVRLDGSTPMAERIGLIDKYNT-NPEIFVFLLSTRAGGQGINLASANTVILHDIDCNPFNDK 904

  Fly  1203 QAQDRAHRIGQRNEVRVLRLMTVNSVEERILAAARYKLNMDEKVIQAGMFDQKSTGSERQQFLQT 1267
            ||:||.||:||...|:|::|::.:|:|:.:|...:.||.:::.:..    |:...|:..:|..:.
Zfish   905 QAEDRCHRMGQTRTVQVIKLISKDSIEDCMLRVGQEKLKLEQDMTT----DEGEDGAITEQMAEL 965

  Fly  1268 I 1268
            :
Zfish   966 L 966

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
brm	NP_001261906.1	QLQ	173..202	CDD:462622
		Pro-rich	<247..401	CDD:464580
		PTZ00121	<477..651	CDD:173412	30/183 (16%)
		HSA	501..573	CDD:214727	13/71 (18%)
		BRK	650..691	CDD:462196	7/47 (15%)
		PLN03142	739..>1368	CDD:215601	204/602 (34%)
		Bromo_SNF2L2	1425..1530	CDD:99947
smarcad1a	NP_001018610.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	15..76		3/12 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	125..177		6/55 (11%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	217..333		25/130 (19%)
		ComEA	<348..>381	CDD:441164	5/32 (16%)
		HepA	<439..944	CDD:440319	195/531 (37%)
		DEGH box	579..582		2/2 (100%)