Protein Alignment brm and lds

DIOPT Version :10

• Sequence 1: NP_001261906.1
• Gene: brm / 39744
• FlyBaseID: FBgn0000212
• Length: 1658
• Species: Drosophila melanogaster
• Sequence 2: NP_524850.2
• Gene: lds / 45894
• FlyBaseID: FBgn0002542
• Length: 1061
• Species: Drosophila melanogaster
• Alignment Length: 1086
• Identity: 237/1086 - (21%)
• Similarity: 411/1086 - (37%)
• Gaps: 344/1086 - (31%)

  Fly   389 KPNRITTVAKPVGLDPITLLQERENRIAARI---SLRMQELQRLPATMSEDLRLQAAIELRALRV 450
            :|:...|..||:|:...:  ::.|:.:..|.   |.||......|..:|:|
  Fly    93 RPSARNTKRKPLGIPSDS--EDEEDELEQRALSPSTRMSITGVRPQDLSDD-------------- 141

  Fly   451 LNFQRQLRMEFVQCTRRDTTLETALNIKLYKRTKRQGLREARATEKL----------EKQQKLEA 505
                             |:.:|       |....::|..||...|.:          ..|..|.:
  Fly   142 -----------------DSEIE-------YSDEVQEGPTEAPTAEAVVPRYTTQFAGNIQNDLHS 182

  Fly   506 E-------------------RKRRQKHLEFLAAVLQHGKDLRE------FHRNNK---------A 536
            .                   ...::..:|.|::........:|      |.|.:|         |
  Fly   183 TIGAADSEVLDDSSGSDVLILSNKETPIEILSSTDDDATTNKENMSGPPFERPSKSLSPRSSAGA 247

  Fly   537 QLARMNKAVMNHHANAEREQKKEQERIEKERMRRLMAEDEEGYRKLIDQKKDKRLAFLLSQTDEY 601
            .:.:.:|.:......|..:||...   ...|..|:.:||::...:::..::.::||....|..:
  Fly   248 SVVKTSKNLSQPTIQAVLKQKTSP---AAPRRSRIKSEDQKVVSQVVYDEEMRKLAEKRVQVSD- 308

  Fly   602 ISNLTQMVKQHKDDQMKKKEEEGKRLIQFKKELLMSGEYIG---IDEGSIVADMRVHVVEQCTGK 663
            ...|.:.|.....|   |..:..||:...::||.|..::|.   :.:.::.|   |.||:    .
  Fly   309 AEKLFEKVAHKLPD---KGSQIMKRIDTLRRELAMDEQWISALRVQQSNVPA---VRVVK----P 363

  Fly   664 KLTGDDAPMLKHLHRWLNMHPGWDWIDDEEDSCGSNDDHKPKVEE-QPTATEDATDKAQATGNDE 727
            .|....||.:..|          ||           |:....|.| :|..|   ..:..||.|::
  Fly   364 TLNPPRAPSIDTL----------DW-----------DELSEAVNEIKPVYT---GAQGMATFNNQ 404

  Fly   728 DAKDLITKAKVEDDEYRTEEQTYYSIAHTIHEKVVEQASIMVNGTLKEYQIKGLEWLVSLYNNNL 792
            .|   :|...::|        .:.|:......:|:.:..:.:..:|..:|...|.|: |.....|
  Fly   405 KA---LTLESLKD--------LHVSLEDLPGPEVLAEDPVGLKVSLMNHQKHALAWM-SWRERKL 457

  Fly   793 --NGILADEMGLGKTIQTISLVTYLMD-----------------------RKKV----------- 821
              .|||||:||||||:..||.|....:                       ||.|
  Fly   458 PRGGILADDMGLGKTLTMISSVLACKNGQEMSEGKDESSDSDSEDDKNKKRKSVTGWKSKGRKDT 522

  Fly   822 -MGPYLIIVPLSTLPNWVLEFEKWAPAVGVVSYKGSPQGRRLL-----QNQMRATK------FNV 874
             .|..|::.|.|.|..|..|.|             |...|:.|     ....|.||      :::
  Fly   523 RRGGTLVVCPASLLRQWESEVE-------------SKVSRQKLTVCVHHGNNRETKGKYLRDYDI 574

  Fly   875 LLTTYEYVIKDKAVLAK---IQWKYMIIDEGHRMKNHH-------CKLTQVLNTHYIAPYRLLLT 929
            ::|||:.|.::...|:.   ::|:.:|:||.|.::||.       |.|.        ..||..||
  Fly   575 VVTTYQIVAREHKSLSAVFGVKWRRIILDEAHVVRNHKSQSSLAVCDLR--------GKYRWALT 631

  Fly   930 GTPLQNKLPELWALLNFLLPSIFKSCSTFEQWFNAPFATTGEKVELNEEETILIIRRLHKVLRPF 994
            |||:|||..:::|||.||..|.|....|:::|.:...| .|:             .||:.:::..
  Fly   632 GTPIQNKELDVYALLKFLRCSPFDDLHTWKKWIDNKSA-GGQ-------------NRLNLLMKSL 682

  Fly   995 LLRRLKKEVE-----HQLPDKVEYII-----KCDMSALQRVL---------YKHMQSKGVLLTD- 1039
            :|||.|.:::     :.||:|...:|     |.:|:..|.|:         :.|.:::..  ||
  Fly   683 MLRRTKAQLQSDGKLNSLPNKELRLIEISLDKEEMNVYQTVMTYSRTLFAQFLHQRAERE--TDF 745

  Fly  1040 ------------------GSEKGKHGK----GGAKA------LMNTIVQLRKLCNHPFMFQHI-- 1074
                              |:....|.|    .|:|.      ::..:::||::|.||.:...:
  Fly   746 NYRSDANKPTYNQIKDPNGAYYKMHEKFARMAGSKKEVKSHDILVLLLRLRQICCHPGLIDAMLD 810

  Fly  1075 -EEKYC--DH------------------------TGGHGVVS-----GP---------------- 1091
             ||...  ||                        |.|...|:     ||
  Fly   811 GEESQTMGDHSSDSDTPEIDLLAQLNKLAITDTSTDGQQSVANAGDDGPPLLPDEARIAKASKNL 875

  Fly  1092 --------DLYRVSGKFELLDRILPK--LKATNHRVLLFCQMTQCMTIIEDYLGWRQFGYLRLDG 1146
                    :|:|.|.|..::.:||..  ||:::.:.::..|.|..:.|:.|:|.......|.|:|
  Fly   876 LKRSNPVFNLHRPSSKINMVIQILKTSILKSSDDKAIVVSQWTSVLDILRDHLSKDGVATLSLNG 940

  Fly  1147 TTKAEDRGELLRKFNAKGSDVFVFLLSTRAGGLGLNLQTADTVVIFDSDWNPHQDLQAQDRAHRI 1211
            |...::|.:::.:||.:.:...|.|||..|||:||||..|:.:::.|..|||..:.|||||.:|:
  Fly   941 TIPVKNRQDIVNEFNDRNNQKRVLLLSLTAGGVGLNLIGANHLLLLDLHWNPQLEAQAQDRIYRV 1005

  Fly  1212 GQRNEVRVLRLMTVNSVEERILAAARYKLNMDEKVIQAGMFDQKST 1257
            ||:..|.:.:.|.|::||:||......||::.:.|:.......|.|
  Fly  1006 GQKKNVIIYKFMCVDTVEQRIKGLQDKKLDLADGVLTGAKVSSKLT 1051

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
brm	NP_001261906.1	QLQ	173..202	CDD:462622
		Pro-rich	<247..401	CDD:464580	4/11 (36%)
		PTZ00121	<477..651	CDD:173412	35/220 (16%)
		HSA	501..573	CDD:214727	14/105 (13%)
		BRK	650..691	CDD:462196	10/40 (25%)
		PLN03142	739..>1368	CDD:215601	167/685 (24%)
		Bromo_SNF2L2	1425..1530	CDD:99947
lds	NP_524850.2	HepA	287..1041	CDD:440319	197/837 (24%)
		DEXHc_TTF2	439..686	CDD:350830	75/282 (27%)