Protein Alignment brm and CG7376

DIOPT Version :10

• Sequence 1: NP_001261906.1
• Gene: brm / 39744
• FlyBaseID: FBgn0000212
• Length: 1658
• Species: Drosophila melanogaster
• Sequence 2: NP_648034.1
• Gene: CG7376 / 38715
• FlyBaseID: FBgn0035689
• Length: 1270
• Species: Drosophila melanogaster
• Alignment Length: 980
• Identity: 198/980 - (20%)
• Similarity: 321/980 - (32%)
• Gaps: 343/980 - (35%)

  Fly   423 MQELQRLPATMS---EDLRLQAAIELRALRVLNFQRQLRMEFV----QCTRRDT--TLETA--LN 476
            :.|.|.:.::.|   |.:|:..||...|:.....:....:|||    .|...|.  |::.|  ||
  Fly   432 LDEAQMVESSTSAAAEMVRMLPAINRWAVTGTIDELPPLLEFVGRPEVCRPPDAWQTVDKAFQLN 496

  Fly   477 IK-----------LYKRTKRQGLREARATEKLEKQQKLEAERKR----RQKHL----EFLAAVLQ 522
            .|           |::..|.:...|.....:.|...:||.....    |::||    :|||||.:
  Fly   497 YKCEPLLELLEHSLWRTCKSKVEHELGIPPQTEVVHRLELSNVESLYYREEHLKCHEQFLAAVAK 561

  Fly   523 HGKDLREFHRNNKAQLARMNKAVMNHHANAEREQKKEQERIEKERMRRLMAEDEEGYRKLIDQKK 587
            |.:    .:.:|.:.||.::..::               ||..:...|            |.|..
  Fly   562 HTR----HNADNSSCLASISPQLL---------------RIILKPFLR------------IRQTC 595

  Fly   588 DKRLAF--LLSQTDEYI--SNLTQMVKQHKDDQMKKK------EEEGKRLIQFKKE--------- 633
            ...:.|  .:|.|| |:  .:|...:|.:.:::.|.:      ...|...|.|.|.
  Fly   596 SVPVVFNSNVSSTD-YLHPQDLLARLKSNNENECKTELRTWASSYNGLAAIYFIKNDFPQAIKYY 659

  Fly   634 ---LLMSGEYIGIDEGSIVAD--MRVHVVEQC--------TGKKLTGDDAPMLKHLHRWLNM-HP 684
               |.::.||   :|.:|..|  :::|.:...        ...|||     .|:|......| ..
  Fly   660 NLLLKLANEY---NEQNISVDSVLQIHAIYNLLQASSLAPAEHKLT-----ELEHKKYQAQMSRL 716

  Fly   685 GWDWIDDE----EDSCGSNDDHKPKVEEQPTATEDATDKAQAT--GNDEDAKDLITKAKVEDDEY 743
            .|.:::|.    |.:..|.:::..||.|.....|.:|....||  .:.....|.|.. ||.||.:
  Fly   717 EWKYLEDNTRVLESALSSYNENLEKVSELEKRFEGSTLDLLATMVNHKTSLHDAIWN-KVRDDFF 780

  Fly   744 RTEEQTYYSIAHTIHEKVVEQASIMVNGTLKEYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQT 808
            |          ..|..:.:|..:.|.          |:.:.:.:::|.|..:
  Fly   781 R----------QNISVERLENVNSMA----------GMLYFMDIWHNKLQNL------------- 812

  Fly   809 ISLVTYLMDRKKVMGPYLIIVPLSTLPNWVLEFEKWAPAVGVVSYKGSPQGRRLLQNQMRATKFN 873
                                  .|||   :.|||         ..||      ::|....|.|..
  Fly   813 ----------------------KSTL---IAEFE---------FLKG------VMQQACEAIKTG 837

  Fly   874 VLLTT-----YEYVI-----------KDKAVLAKIQWKYMIIDEGHRMKNHHCKLTQVLNTHYIA 922
            |||:.     .|.|.           |||.|..|              |:.:|:|..:.::  :.
  Fly   838 VLLSMEIINFIENVTVCHLTDILDANKDKPVKPK--------------KHRYCRLCLIRDS--LN 886

  Fly   923 PYRLLLTGTPLQNKLPELWALLN-----FLLPSIF---KSCSTFEQWFNAPFATTGEKVELNEEE 979
            .:..||....|..|......|.|     ..:.|||   :|...|.:|          |.|...:.
  Fly   887 QFECLLFAKKLDEKATVTEGLENPSMEISFIKSIFAFLRSKQDFSEW----------KEECQSKL 941

  Fly   980 TILIIRRLHKVLRPFLLRRLKKEVEHQLPDKVEYIIK-------CDMSALQRVLYKHMQSKGVLL 1037
            .:|      ..|:..:..::|..:|      |||::|       |.|.              :||
  Fly   942 ELL------SCLQDLVKFQIKYWIE------VEYMVKAFDELEMCKMR--------------ILL 980

  Fly  1038 TDGSEKGKHGK-----------GGAKALMNTIVQLRKLCNHPFMFQHIEE--------------- 1076
            ||..|:..:.:           .....|..:.:...:||......:|::|
  Fly   981 TDDPEEQSNYRILACQLDEQLQFNQYNLQTSQLNFTRLCGRLKYLKHLKEDSADKPCPICQTQDD 1045

  Fly  1077 -KY---------CDH--------TGGHGVV-------SGPDLY-------------RVSGKFELL 1103
             :|         |.|        .|..||.       ..|.||             ..|.|...:
  Fly  1046 VRYVMMVCGHFVCQHCLDSMRRKNGRAGVTKCPLCRQDSPQLYYSVRPGAHKSIIGDFSTKISSV 1110

  Fly  1104 DRILPKLKATN--HRVLLFCQMTQCMTIIEDYLGWR--QFGYLRLDGTTKAEDRGELLRKFNAKG 1164
            ..::.|:|..|  .::::|.|....:..|...|...  ||   |...|.|..|      .|....
  Fly  1111 VELVLKIKGENEQEKIIVFSQWQAILIEIARALSLNGIQF---RNKCTNKDFD------DFKNPL 1166

  Fly  1165 SDVFVFLLSTRAGGLGLNLQTADTVVIFDSDWNPHQDLQAQDRAHRIGQRNEVRVLRLMTVNSVE 1229
            |:|...|:....|..||||..|..|.:.:...||..:.||..|.||.||:...:|.|.:...::|
  Fly  1167 SNVTCLLMPLSKGSKGLNLIEATHVFLVEPILNPGDERQAIGRIHRFGQKRPTKVHRFIVNETIE 1231

  Fly  1230 ERILA 1234
            |.||:
  Fly  1232 ENILS 1236

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
brm	NP_001261906.1	QLQ	173..202	CDD:462622
		Pro-rich	<247..401	CDD:464580
		PTZ00121	<477..651	CDD:173412	41/214 (19%)
		HSA	501..573	CDD:214727	17/79 (22%)
		BRK	650..691	CDD:462196	9/51 (18%)
		PLN03142	739..>1368	CDD:215601	117/595 (20%)
		Bromo_SNF2L2	1425..1530	CDD:99947
CG7376	NP_648034.1	DEXQc_SHPRH	160..513	CDD:350828	19/80 (24%)
		PHD_SF	281..320	CDD:473978
		TPR	636..669	CDD:197478	5/32 (16%)
		RING_Ubox	1036..1082	CDD:473075	6/45 (13%)
		SF2_C_SNF	1104..1225	CDD:350180	37/129 (29%)