Protein Alignment brm and Marcal1

DIOPT Version :10

• Sequence 1: NP_001261906.1
• Gene: brm / 39744
• FlyBaseID: FBgn0000212
• Length: 1658
• Species: Drosophila melanogaster
• Sequence 2: NP_608883.1
• Gene: Marcal1 / 33709
• FlyBaseID: FBgn0031655
• Length: 755
• Species: Drosophila melanogaster
• Alignment Length: 847
• Identity: 178/847 - (21%)
• Similarity: 323/847 - (38%)
• Gaps: 201/847 - (23%)

  Fly   561 ERIEKER--MRRLMAEDEEGYRKLIDQKKDKRLAFLLSQTDEYISNLTQMVKQHKDDQMKKKEEE 623
            |..||:|  :.:|.|            ||.:.||...:...:..::.|...:...:.:....:.:
  Fly     8 EIAEKKRIALAKLQA------------KKSQLLASAPATNGKSTTSATGATQHANNGKSNPNQPQ 60

  Fly   624 GKRLIQF-------KKELLMSGEYIGIDEGSIVADMRVHVVEQCTGKKLTGDDAPMLKHLHRWLN 681
            .|..:.|       :|::..||...|.::.|...: .:..::|.:.::|:...|
  Fly    61 AKSPLNFYRSPTGEQKKINRSGPTPGDNKSSSFLN-ALKAIKQTSNRELSRGAA----------- 113

  Fly   682 MHPGWDWIDDEEDSCGSNDDHKPKV-----EEQPTAT-------------EDATDKAQATGNDED 728
             ||       .:...|.|:.:||.:     :|:|.|.             ......||.:|..|.
  Fly   114 -HP-------YQRPNGGNERNKPTLSLSSDKEKPVAVLLGNSITCNLYLISTHRFAAQTSGYHEQ 170

  Fly   729 A----KDLITKA--------KVEDDEYRTEEQTYYSIAHTIH--------------EKVVEQASI 767
            .    |::.||.        ..:..:|::.:.....:...:|              ..||.:.|:
  Fly   171 LVTVFKNMPTKCYDGQTRIWSFDLSDYQSLKTHAADLKPYVHMNGIPKKVLDLCGQPPVVPERSV 235

  Fly   768 MVN------GTLKEYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTISLVTYLMDRKKVMGPYL 826
            :.:      ..|..:|..|:.:.::.....:   :.||||||||.|.:::..|..|.    .|.|
  Fly   236 LASIEPKLADQLMPFQQDGVCFAIAQKGRIM---ICDEMGLGKTYQALAVADYFKDD----WPLL 293

  Fly   827 IIVPLSTLPNWVLEFEKWAPAVGVVSYKGSPQGRRLLQNQMRATKFNVLLTTYEYVIKDKAVLAK 891
            :....||..:|........|.| .:.|.     :.|..||:...:..||:|:|..:.:.:..|.:
  Fly   294 VCTTASTRDSWAKHIMDLLPKV-PIHYV-----QVLNNNQLYVGEAKVLITSYNMMERHEDKLMQ 352

  Fly   892 IQWKYMIIDEGHRMKNHHCKLTQVLNTHYIAPYR-LLLTGTPLQNKLPELWALLNFLLPSIFKSC 955
            .::.::|.||.|.:||...|.|...........| :||:|||..::..||:..|..:........
  Fly   353 RKFGFIIFDESHTLKNSKAKCTTTAKRLTDQAKRVVLLSGTPALSRPLELFTQLQMIDGKFMNFM 417

  Fly   956 STFEQWFNAPFATTG----EKVELNEEETILIIRRLHKVLRPFLLRRLKKEVEHQLPDKVEYIIK 1016
            ....::.:...:|.|    .:..|.|.:.||.::        ::|||.|.||..||.:|....:.
  Fly   418 EFTTRYCDGKQSTFGWDANGQSNLEELKVILHLK--------YMLRRTKVEVLPQLAEKNRETVV 474

  Fly  1017 CDMSALQRVLYKHMQSKGVLLTDGSE-KGKHGKGGAKALM-----NTIVQLRKLCNHPFMFQHIE 1075
            .|.:    :::.:.::|..|.....| |...|:...:.|:     ...|:.|.:|.:.
  Fly   475 LDPA----LVWTNAETKETLDAFNKELKTAKGRATEEILLRFYARTAEVKTRAVCAYL------- 528

  Fly  1076 EKYCDHTGGHGVVSGPDLYRVSGKFELLDRILPKLKATNHRVLLFCQMTQCMTIIEDYLGWRQFG 1140
                           ..|.:...||.:.         .:|||:        |..|.|:|...:..
  Fly   529 ---------------KTLVKEQKKFIIF---------AHHRVM--------MDAISDFLSGLKVH 561

  Fly  1141 YLRLDGTTKAEDRGELLRKFNAKGSDVFVFLLSTRAGGLGLNLQTADTVVIFDSDWNPHQDLQAQ 1205
            |:|:||.|:::.|.:.:..|..| |...|.|||.:|...|:.|..|:.:|..:.||||....||:
  Fly   562 YIRIDGQTRSDHRSDSVDTFQKK-SSCKVALLSLKACNSGITLTAAEIIVFAELDWNPSTLAQAE 625

  Fly  1206 DRAHRIGQRNEVRVLRLMTVNSVEERILAAARYKLNMDEKVIQAGMFD---QKSTGS-------- 1259
            .|||||||...|....|:..|:.::.|....:   |..|.:.:.|:|.   ||:|.:
  Fly   626 SRAHRIGQTKPVICRYLIAHNTADDIIWNMLK---NKQEVLSKVGIFAENLQKATHTAAPTSSHK 687

  Fly  1260 ---------------ER---QQFLQTILHQDDNEEEEENEVPDDEMINMMIAR--SEEEIEIFKR 1304
                           ||   :|:..||..::..|:....|:.........||.  ::::.|.|..
  Fly   688 IEEYFSPSTSTSLEPERNSIKQYFSTIPAKEPPEQNNNTEMTKVNKAESDIAAFFNDDDDEAFLE 752

  Fly  1305 MD 1306
            :|
  Fly   753 LD 754

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
brm	NP_001261906.1	QLQ	173..202	CDD:462622
		Pro-rich	<247..401	CDD:464580
		PTZ00121	<477..651	CDD:173412	18/98 (18%)
		HSA	501..573	CDD:214727	5/13 (38%)
		BRK	650..691	CDD:462196	5/40 (13%)
		PLN03142	739..>1368	CDD:215601	141/630 (22%)
		Bromo_SNF2L2	1425..1530	CDD:99947
Marcal1	NP_608883.1	HARP	160..216	CDD:462166	9/55 (16%)
		HepA	<233..666	CDD:440319	120/500 (24%)
		DEXHc_HARP_SMARCAL1	247..456	CDD:350768	54/229 (24%)