Protein Alignment brm and okr

DIOPT Version :10

• Sequence 1: NP_001261906.1
• Gene: brm / 39744
• FlyBaseID: FBgn0000212
• Length: 1658
• Species: Drosophila melanogaster
• Sequence 2: XP_557901.4
• Gene: okr / 3291801
• VectorBaseID: AGAMI1_012486
• Length: 791
• Species: Anopheles gambiae
• Alignment Length: 739
• Identity: 202/739 - (27%)
• Similarity: 336/739 - (45%)
• Gaps: 153/739 - (20%)

  Fly   756 TIHEKV-VEQASIMVN--------GTLKEYQIKGLEWL---VSLYNNNLNG-ILADEMGLGKTIQ 807
            |.|:|: ::::.|.|:        ..|:.:|.:|:.::   |:....:.|| |:|||||||||:|
Mosquito   114 TEHDKLKMDKSKIQVHVVVDPLLGNILRPHQREGVRFMYDCVTGAKGDFNGCIMADEMGLGKTLQ 178

  Fly   808 TISLVTYLM----DRKKVMGPYLIIVPLSTLPNWVLEFEKWAPA-VGVVSYKGSPQGR------R 861
            .|:|:..|:    |.|..:...:|:.|.|.:.||..||.||... |..:|..|..:.:      :
Mosquito   179 CITLLWTLLRQSPDCKPTINKAIIVCPSSLVKNWYKEFGKWLGCRVNCLSIDGGSKEQTTKELEQ 243

  Fly   862 LLQNQMRATKFNVLLTTYE------YVIKDKAVLAKIQWKYMIIDEGHRMKNHHCKLTQVLNTHY 920
            .:.||.:.....||:.:||      :::....|.|      ::.|||||:||  |:     |..|
Mosquito   244 YMANQSQRHGTPVLIISYETFRLYAHILNSSEVGA------VLCDEGHRLKN--CE-----NLTY 295

  Fly   921 IA------PYRLLLTGTPLQNKLPELWALLNFLLPSIFKSCSTFEQWFNAPF-------ATTGEK 972
            .|      ..|:||:|||:||.|.|.::||:|:.|.:..|.:.|.:.|..|.       :|..|:
Mosquito   296 QALMGLKTKRRVLLSGTPIQNDLTEYYSLLHFVNPGMLGSTAEFRKQFENPILRGQDANSTDAER 360

  Fly   973 VELNEEETILIIRRLHKVLRPFLLRRLKKEVEHQLPDKVEYIIKCDMSALQRVLYKHMQSKGVLL 1037
            .:..|.     ::.|..::...::||....:...||.|.|.::...|:.:|..|||.......:.
Mosquito   361 EKAAER-----LQELAALVNRCMIRRTSALLTKYLPVKFEMVVCVRMTEVQAALYKSFLQSDTIR 420

  Fly  1038 TDGSEKGKHGKGGAKALMNTIVQLRKLCNHP-FMFQHIEEKYCDHTGGHGVVSGPDLY------- 1094
            ....||.. .|....||.| |..|:|||||| .:::.|:|:.........::  ||.|
Mosquito   421 RSVMEKNA-TKASLTALSN-ITSLKKLCNHPDLVYEKIQERADGFENAATIL--PDNYSPRELRP 481

  Fly  1095 RVSGKFELLDRILPKLKA-TNHRVLLFCQMTQCMTIIEDYLGWRQFGYLRLDGTTKAEDRGELLR 1158
            .:..|..|||.:|..:|. |..:::|....||.:.:.|.....|.:||:|||||...:.||:::.
Mosquito   482 ELGAKLMLLDCMLASIKTNTTDKIVLVSNYTQTLDLFEKLCRKRGYGYVRLDGTMTIKKRGKVVD 546

  Fly  1159 KFNAKGSDVFVFLLSTRAGGLGLNLQTADTVVIFDSDWNPHQDLQAQDRAHRIGQRNEVRVLRLM 1223
            :||...|..|:|:||::|||.||||..|:.:|:||.||||..|.||..|..|.||:....:.||:
Mosquito   547 QFNQPDSADFIFMLSSKAGGCGLNLIGANRLVMFDPDWNPANDEQAMARVWRDGQKKPCFIYRLL 611

  Fly  1224 TVNSVEERILAAARYKLNMDEKVIQAGMFDQKSTGSERQQFLQTILHQDDNEEEEENEVPDDEMI 1288
            ...::||:|.....:|..:...|:                         ||.|:.|.....|::
Mosquito   612 ATGTIEEKIFQRQTHKKALSTTVV-------------------------DNAEDGERHFTQDDL- 650

  Fly  1289 NMMIARSEEEIEIFKRMDAERKKEDEEIH------PGRERLI--DESE----------------L 1329
                      .::|| :|.:.:.:..:|.      .|.:..:  |:|:                :
Mosquito   651 ----------KDLFK-LDEQTRSDTHDIFRCKRCTNGVQMKLPPDDSDCMSDLAHWYHCANNKGI 704

  Fly  1330 PDWLTKDDDEVER-----FHYQYDEDTILGRGSRQRKEVDYTDSLTEKEWLKAIDDGAEFDEEEE 1389
            ||.:.....::.|     ||::.:...:..:.:.||::........||          |.:||||
Mosquito   705 PDDILSKSWDITRCVSFVFHHRSNSAVVEQQLAEQRRQQALAKEREEK----------EEEEEEE 759

  Fly  1390 EDDSKRK---RRKRKNRKEESDDD 1410
            |:|.:.|   ....:..:||||||
Mosquito   760 EEDKENKGYNTEGEEEEEEESDDD 783

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
brm	NP_001261906.1	QLQ	173..202	CDD:462622
		Pro-rich	<247..401	CDD:464580
		PTZ00121	<477..651	CDD:173412
		HSA	501..573	CDD:214727
		BRK	650..691	CDD:462196
		PLN03142	739..>1368	CDD:215601	186/692 (27%)
		Bromo_SNF2L2	1425..1530	CDD:99947
okr	XP_557901.4	None