|
Fly 1 MASPSPANSPMPPPQAP----------------------------SPMAPPSQSPAPSPHSPYPH 37
:|||.......|.||.| |...|.:........:||..
Mouse 97 LASPHSQYHTPPVPQVPHGGGGGGQMGVYPGIQNERHGQSFVDGGSMWGPRAVQVPDQIRAPYQQ 161
Fly 38 QQPGPL-QGPPPPGHP------GAY-----GHPMQHGPP----GQGPPGHHMPPHHQGMIFSKGP 86
|||.|. .|||..||| |:| ....|||.| ||...|..........|.:.||
Mouse 162 QQPQPAPSGPPAQGHPQHMQQMGSYLARGDFSMQQHGQPQQRMGQFSQGQEGLSQGSPFIATSGP 226
Fly 87 HMGMQMPPTGPNMSPYQTHGMPPNAPTQPCIV-----------SPGGPPGG-------------- 126
.....||...|:|:|...|.:.......|..: ||..|..|
Mouse 227 GHLSHMPQQSPSMAPSLRHPVQQQFHHHPAALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRNQ 291
Fly 127 --PPPPERSSQE-------NLH-ALQRAIDSMEEKGL-------QEDPRYSQLLAMRATS----K 170
|.|...:|.: ||: .|..:....:..|| |..|||...:...:.| .
Mouse 292 TVPSPTVNNSGQYSRYPYSNLNQGLVNSTGMNQNLGLTNSTPMNQSVPRYPNAVGFPSNSGQGLV 356
Fly 171 HQ---HLNGNQVNLLRTQITAYRLLARNKPISMQMQQALQAAQQQPPPGPPIGPPGAPGGPPPGS 232
|| |.:|: :|.:.|| :|...|. |.....|||..|:.....|.|.||..
Mouse 357 HQQPIHSSGS-LNQMNTQ-------------TMHPSQP-QGTYASPPPMSPMKAMSNPAGTPPPQ 406
Fly 233 QHAGQPPVP-----------PQQQQQPPPSAGTPPQCSTPPASNPYGPPVPGQKMQVAPPPPHMQ 286
...|...:| ||...|||.:.|...: ...|.....|...|.::..|..:
Mouse 407 VRPGSAGMPMEVGSYPNMPHPQPSHQPPGAMGIGQR-----NMGPRNMQQPRSFMGMSSAPREL- 465
Fly 287 QGQPLPPQPPQVG--GPPPIQQQQPPQQQQQQSQP--------PPPEPHQ--HQLPNGGKPLSMG 339
.|...|...|.|| .|..||::..|.||....|| ||.:||. ||
Mouse 466 TGHMRPNGCPGVGLADPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHQ----------- 519
Fly 340 PSGGQPLIPSSPMQPQVRGTLPGMPPGSQV-PQPGGGPQR----QVPPAG--MPMPKPNRITTVA 397
|||..|..: |.:|: |.|...||: |..|:. :..|.|:.....|
Mouse 520 ---------SSPPHPHHQ-------PWAQLHPSPQNTPQKVPVHQHSPSEPFLEKPVPDMTQVSA 568
Fly 398 KPVGL----DPITLLQE---------RENRIAARIS------------LRMQELQRL-------- 429
:...| |.:..::: :.|.|||..| :..|||:|.
Mouse 569 QNAQLVKSDDYLPSIEQQPQQKKKKKKNNHIAAGDSSKGFGKDDFPGGVENQELRRNSLDVSQEE 633
Fly 430 ------------PATMSEDLRLQAAIELRALRVLNFQRQLRMEFV----QCTRRDTTLETALNIK 478
|....|....:.....:|.::....::.:.:.| :.:::.:..:......
Mouse 634 KKKKKRPKVKKDPKESKEPKEKKEPKTPKAPKIPKEPKEKKAKTVTPKPKSSKKSSNKKPDSEAS 698
Fly 479 LYKRTKRQGLREARATEKLEK-------------------QQKLEAERKRRQKHLEFLAAVLQHG 524
..|:...:|..|......|:| :...:.:|||..:.|||..:. :..
Mouse 699 ALKKKVNKGKTEGSENSDLDKTPPPSPAPEEDEDPGVQKRRSSRQVKRKRYTEDLEFKISD-EEA 762
Fly 525 KDLREFHRNNKAQLARMNKAVMNHHANAEREQKKEQER--IEKERMRRLM---------AEDEEG 578
.|.....|::.:..:: :|:::..:.|. :||....||: .|.||.
Mouse 763 DDADAAGRDSPSNTSQ-----------SEQQESVDAEGPVVEKIMSSRLVKKQKESGEEVEVEEF 816
Fly 579 YRK-------------LIDQKKDKRLAFLLSQTDEYISNLTQMVKQHKDDQMKKKEEEGKRLIQF 630
|.| :.|.:||||: |.|..:.|.|:.:.|.|.:.
Mouse 817 YVKYKNFSYLHCQWASVEDLEKDKRI-------------------QQKIKRFKSKQGQSKFLSEI 862
Fly 631 KKELLMSGEYIGIDEGSIVADMRVHVVEQCTGKKLTGDD--APMLKHLHRWLNMHPGWDWIDDEE 693
:.: |.:.:|:.:| |:....:.| || .|::.:|.:|.:: ..|
Mouse 863 EDD-LFNPDYVEVD--------RIMDFARST------DDRGEPVIHYLVKWCSL--------PYE 904
Fly 694 DSCG--SNDDHKPKVE--EQPTATEDATDKAQATGNDEDAKDLITKAKVEDDEYRTEEQTYYSIA 754
||.. ..|..:.|:| |:..:.|..|::.:....|: .|......||:.
Mouse 905 DSTWELKQDIDQTKIEEFEKLMSREPETERVERPPADD------WKKSESSREYKN--------- 954
Fly 755 HTIHEKVVEQASIMVNGTLKEYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTISLVTYLMDRK 819
|..|:|||::|:.||:..:.|..|.|||||||||||||:|:.: |.:..|
Mouse 955 ---------------NNKLREYQLEGVNWLLFNWYNMRNCILADEMGLGKTIQSITFL-YEIYLK 1003
Fly 820 KVMGPYLIIVPLSTLPNWVLEFEKWAPAVGVVSYKGSPQGRRLLQ--------NQMR----ATKF 872
.:.||:|:|.||||:|||..||..|. .:.||.|.||...||.:| .|.| :.||
Mouse 1004 GIHGPFLVIAPLSTIPNWEREFRTWT-ELNVVVYHGSQASRRTIQLYEMYFKDPQGRVIKGSYKF 1067
Fly 873 NVLLTTYEYVIKDKAVLAKIQWKYMIIDEGHRMKNHHCKLTQVLNTHYIAPYRLLLTGTPLQNKL 937
:.::||:|.::.|...|..|.|:.::|||.||:||.:|||.:.|....: .:::|||||||||.:
Mouse 1068 HAIITTFEMILTDCPELRNIPWRCVVIDEAHRLKNRNCKLLEGLKMMDL-EHKVLLTGTPLQNTV 1131
Fly 938 PELWALLNFLLPSIFKSCSTFEQWFNAPFATTGEKVELNEEETILIIRRLHKVLRPFLLRRLKKE 1002
.||::||:||.||.|.|.:||.|.|. :|..||. :::|..:|:|.:|||||::
Mouse 1132 EELFSLLHFLEPSRFPSETTFMQEFG----------DLKTEEQ---VQKLQAILKPMMLRRLKED 1183
Fly 1003 VEHQLPDKVEYIIKCDMSALQRVLYKHMQSKGVLLTDGSEKGKHGKGGAKA----LMNTIVQLRK 1063
||..|..|.|.||:.:::.:|:..|:.:..|..... .|||.:| |:||:::|||
Mouse 1184 VEKNLAPKEETIIEVELTNIQKKYYRAILEKNFTFL--------SKGGGQANVPNLLNTMMELRK 1240
Fly 1064 LCNHPFMFQHIEEKYCDHTGGHGVVSGPD-----LYRVSGKFELLDRILPKLKATNHRVLLFCQM 1123
.||||::....|||..:..........|| :.:.:||..|:|::||||||..||||:|.||
Mouse 1241 CCNHPYLINGAEEKILEEFKETHNAESPDFQLQAMIQAAGKLVLIDKLLPKLKAGGHRVLIFSQM 1305
Fly 1124 TQCMTIIEDYLGWRQFGYLRLDGTTKAEDRGELLRKFNAKGSDVFVFLLSTRAGGLGLNLQTADT 1188
.:|:.|:||||..|::.|.|:||..:...|...:.:|:...||.|||||.|||||||:||..|||
Mouse 1306 VRCLDILEDYLIQRRYPYERIDGRVRGNLRQAAIDRFSKPDSDRFVFLLCTRAGGLGINLTAADT 1370
Fly 1189 VVIFDSDWNPHQDLQAQDRAHRIGQRNEVRVLRLMTVNSVEERILAAARYKLNMDEKVIQAGMFD 1253
.:||||||||..|||||.|.|||||...|::.||:|.||.|..:...|..||.:|:.|:|:....
Mouse 1371 CIIFDSDWNPQNDLQAQARCHRIGQSKSVKIYRLITRNSYEREMFDKASLKLGLDKAVLQSMSGR 1435
Fly 1254 QKSTGSERQ---QFLQTILHQDD----NEEEEENEVPDDEMINMMIARSEEEIEIFKRMDAERKK 1311
:.:|...:| :.::.:|.:.. .:||:|.....:|.|:.::.|....|.|..........
Mouse 1436 ENATNGVQQLSKKEIEDLLRKGAYGALMDEEDEGSKFCEEDIDQILLRRTHTITIESEGKGSTFA 1500
Fly 1312 EDEEIHPGRE---RLIDESELPDWLTKDDDEVERFHYQYDEDTILGRGS------RQRKEVDYTD 1367
:...:..|.. .|.|.:....|..| .:.|.|.:.||.: |.||:.....
Mouse 1501 KASFVASGNRTDISLDDPNFWQKWAKK---------AELDIDALNGRNNLVIDTPRVRKQTRLYS 1556
Fly 1368 SLTEKEWLKAIDDGAEFDEEEE--------EDDSKRKRRKRKNRKEES--------DDDSLILKR 1416
::.|.|.::..| .|.|.||: :|.|:...|....|.|:: ..|.|...|
Mouse 1557 AVKEDELMEFSD--LESDSEEKPCAKPRRPQDKSQGYARSECFRVEKNLLVYGWGRWTDILSHGR 1619
Fly 1417 RRRQNLDK-----------------RSKKQMHKIMSAVIKHNQDGRT--------LSEPF----- 1451
.:||..:: |..:.:...:..:|....||:| ||.|.
Mouse 1620 YKRQLTEQDVETICRAILVYCLNHYRGDENIKSFIWDLITPTADGQTRALLNHSGLSAPVPRGRK 1684
Fly 1452 ---MKLPSRQRL-----------PD-------YYEIIKRPVDIKKILQRIEDCKYADLNELEKDF 1495
:|..|.|.: || |.:.:|. ...|:|.|:....|.....:....
Mouse 1685 GKKVKAQSTQPVVHDAHWLASCNPDALFQEDSYKKHLKH--HCNKVLLRVRMLYYLRQEVIGDQA 1747
Fly 1496 MQLCQNA----------QIYNEEASLIYLDSIALQKVFVGA-------------------RQRIT 1531
.::.:.| :.::.|....:.|..|.:.:.:|. .:|:
Mouse 1748 EKILEGADSSEADVWIPEPFHAEVPTDWWDREADKSLLIGVFKHGYEKYNSMRADPALCFLERV- 1811
Fly 1532 AAADAAAVAAGDNTGEAHGNGGSDNSDNDDDDGGDDGSDDE--EIATTSAAAVKMKLKLNKSLAS 1594
...||.|:||.....:...:|| |||:...:|| |...|.| ..|.:::: .|:
Mouse 1812 GMPDAKAIAAEQRGTDMLADGG---------DGGEFDREDEDPEYKPTRA---PFKDEIDE-FAN 1863
Fly 1595 APATPTQSSSNV-SSGA-------------ATTSKKQTRRKR----SQKKY 1627
:||...:.|..| |||. ..||...||.:| .|:.|
Mouse 1864 SPAEDKEESMEVHSSGKHSESNAELGQLYWPNTSTLTTRLRRLITAYQRSY 1914
| 
