Protein Alignment brm and Smarcad1

DIOPT Version :10

• Sequence 1: NP_001261906.1
• Gene: brm / 39744
• FlyBaseID: FBgn0000212
• Length: 1658
• Species: Drosophila melanogaster
• Sequence 2: XP_038963492.1
• Gene: Smarcad1 / 312398
• RGDID: 1309640
• Length: 1033
• Species: Rattus norvegicus
• Alignment Length: 1105
• Identity: 288/1105 - (26%)
• Similarity: 471/1105 - (42%)
• Gaps: 292/1105 - (26%)

  Fly   307 QQPPQQQQQQSQPPPPEPHQHQLPNGGKPLSMGP----SGGQPLIPSSPMQPQVRGTLPGMPPGS 367
            ::.|:...|.|||.|           ..|:|:..    :.|:....::|.......|     ..|
  Rat    18 EEAPEAAPQPSQPGP-----------SSPISLSAEEENAEGEVSRANTPDSDVTEKT-----EDS 66

  Fly   368 QVPQPGGGP----------QRQVP-----PAGMPMPKPNRITTV-AKPVGLDPITLLQE------ 410
            .||:|....          ||.:.     .:......||..:|| .|....|.:.::.|
  Rat    67 SVPEPPDNESKASLSCFQNQRTIQEYIDLSSDSEDVSPNCSSTVQEKKFSKDTVIIVSEPSEDEE 131

  Fly   411 --------RENRIAARISLRMQELQRLPATMSEDLRLQAAIELRALRVLNFQRQLRMEFVQCTRR 467
                    |.|.|:....|  .||:.|     :|.:||...||       |.::...:.::....
  Rat   132 SHDLPSATRRNDISELEDL--SELEDL-----KDAKLQTLKEL-------FPQRSDSDLLKLIDS 182

  Fly   468 DTTLETALNIKLYK---------RTKRQGLREARATEKLEKQQKLEAERKRRQKHLEFLAAVLQH 523
            .:|::.|:...|.|         :.|.....||...::....|.|:..|..|::
  Rat   183 TSTMDGAIAAALLKFGDAGGGPRKRKLSSSSEAYEEDEANDDQSLKKPRGDRRE----------- 236

  Fly   524 GKDLREFHRNNKAQLARMNKAVMNHHANAEREQ------KKEQERIEKERMRRLMAEDEEGYRKL 582
                   ..|..|:.:          :|.|:::      :||....:|:.:|.::.|.|..|.:.
  Rat   237 -------ESNESAEAS----------SNWEKQESIVLKLQKEFPNFDKQELREVLKEHEWMYTEA 284

  Fly   583 IDQKK------DKRLAFLLSQTD-----------EYISNLTQMVKQHKDDQMKKK---EEEGKRL 627
            ::..|      |.:.|   ||::           .|..|..: :|..:...||.:   .::.|:.
  Rat   285 LESLKVFAEDQDVQCA---SQSEVTNGKEVARNQNYSKNAAK-IKMKQKISMKPQNGFNKKRKKN 345

  Fly   628 IQFKKELLMSGEY-IGIDEGS-----------IVAD----MRVHVVEQCTGKKLTGDDAPMLKHL 676
            :...|:.:...|| .|.|.||           ::.|    ..:|.::..:..:||.......|..
  Rat   346 VFNPKKAVEDSEYDSGSDAGSSLDEDYSSCEEVMEDGYKGKILHFLQDASIGELTLIPKCSQKKA 410

  Fly   677 HRWLNMHP--GWDWIDDEEDSCGSNDDHKPKVEEQPTATEDATDKAQATGNDED----------A 729
            .:.:.:.|  .|:.:                          .|..::..|..||          .
  Rat   411 QKIIELRPFNNWETL--------------------------FTKMSKINGLSEDLIWNCKTVIQE 449

  Fly   730 KDLITKA--KVEDDEYRTEEQTYYSIAHTIHEKV-----------VEQASIMVNG-TLKEYQIKG 780
            :|::.:.  |.||            |::.:.::|           :||.|::... :||.||..|
  Rat   450 RDVVIRLMNKCED------------ISNKLTKQVTMLTGNGGGWNIEQPSLLNQSLSLKPYQKVG 502

  Fly   781 LEWLVSLYNNNLNGILADEMGLGKTIQTISLVTYLMDRKKVMGPYLIIVPLSTLPNWVLEFEKWA 845
            |.||..::.:.||||||||||||||||.|:.:.||..... .||:||:||.||:.||:.|...|.
  Rat   503 LNWLALVHKHGLNGILADEMGLGKTIQAIAFLAYLFQEGN-KGPHLIVVPASTIDNWLREVNLWC 566

  Fly   846 PAVGVVSYKGSPQGRRLLQNQM--RATKFNVLLTTYEYVIK---DKAVLAKIQWKYMIIDEGHRM 905
            |.:.|:.|.||.:.|:.::..:  :...:||::|||...|.   |:::..:::..|.|.||||.:
  Rat   567 PTLNVLCYYGSQEERKQIRFNIHNKYEDYNVIVTTYNCAISSSDDRSLFRRLKLNYAIFDEGHML 631

  Fly   906 KNHHCKLTQVLNTHYI---APYRLLLTGTPLQNKLPELWALLNFLLPSIF-KSCSTFEQWFNAPF 966
            ||    :..:...|.:   |..||||||||:||.|.||.:||||::|.:| .|.|...:.|::..
  Rat   632 KN----MGSIRYQHLMTINARNRLLLTGTPVQNNLLELMSLLNFVMPHMFSSSTSEIRRMFSSKT 692

  Fly   967 ATTGEKVELNEEETILIIRRLHKVLRPFLLRRLKKEVEHQLPDKVEYIIKCDMSALQRVLYKHMQ 1031
            ....|: .:.|:|.   |....::::||:|||:|:||...||.|.:.|..|.||..|..||..:.
  Rat   693 KPADEQ-SIYEKER---IAHAKQIIKPFILRRVKEEVLKLLPPKKDQIELCAMSEKQEQLYSGLF 753

  Fly  1032 SKGVLLTDGSEKGKHGKGGAKALMNTIVQLRKLCNHPFMFQHI---------------EEKYCDH 1081
            ::.....:..||...       :.|.::||||:.|||.:.:..               |..:|:
  Rat   754 NRLKKSINNLEKNTE-------MCNVMMQLRKMANHPLLHRQYYTAEKLKEMSQLMLKEPTHCE- 810

  Fly  1082 TGGHGVVSGPDL-------------------------YRV-------SGKFELLDRILPKLKATN 1114
                   :.|||                         |::       ||||..|..||.:||...
  Rat   811 -------ANPDLIFEDMEVMTDFELHVLCKQYQHINSYQLDMDLILDSGKFRTLGCILSELKQKG 868

  Fly  1115 HRVLLFCQMTQCMTIIEDYLGWRQFGYLRLDGTTKAEDRGELLRKFNAKGSDVFVFLLSTRAGGL 1179
            .||:||.|.|..:.|:|..|...|..||||||.|:..:|..|:.:||. ..|:|||||||:||||
  Rat   869 DRVVLFSQFTMMLDILEVLLKHHQHRYLRLDGKTQISERIHLIDEFNT-DMDIFVFLLSTKAGGL 932

  Fly  1180 GLNLQTADTVVIFDSDWNPHQDLQAQDRAHRIGQRNEVRVLRLMTVNSVEERILAAARYKLNMDE 1244
            |:||.:|:.|::.|.|.||:.|.||:||.||:||..||.|::|::..::||.:|...:.||.:::
  Rat   933 GINLTSANVVILHDIDCNPYNDKQAEDRCHRVGQTKEVLVIKLISQGTIEESMLKINQQKLKLEQ 997

  Fly  1245  1244
              Rat   998  997

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
brm	NP_001261906.1	QLQ	173..202	CDD:462622
		Pro-rich	<247..401	CDD:464580	22/113 (19%)
		PTZ00121	<477..651	CDD:173412	38/220 (17%)
		HSA	501..573	CDD:214727	12/77 (16%)
		BRK	650..691	CDD:462196	7/46 (15%)
		PLN03142	739..>1368	CDD:215601	198/574 (34%)
		Bromo_SNF2L2	1425..1530	CDD:99947
Smarcad1	XP_038963492.1	HepA	<484..995	CDD:440319	194/535 (36%)