Protein Alignment brm and snf21

DIOPT Version :10

• Sequence 1: NP_001261906.1
• Gene: brm / 39744
• FlyBaseID: FBgn0000212
• Length: 1658
• Species: Drosophila melanogaster
• Sequence 2: NP_594861.1
• Gene: snf21 / 2542638
• PomBaseID: SPAC1250.01
• Length: 1199
• Species: Schizosaccharomyces pombe
• Alignment Length: 1148
• Identity: 503/1148 - (43%)
• Similarity: 697/1148 - (60%)
• Gaps: 179/1148 - (15%)

  Fly   412 ENRIAARISLRMQELQRLPATM---------SEDLRL-----QAAIELRALRVLNFQRQLRMEFV 462
            ::.|..|:..||.:|:..||.|         :|.|.|     .|.:||:.||::..|..||.:.:
pombe   154 DDAIKNRMFRRMSDLESYPAVMRDVAELKDDNERLNLDTIKRNALVELKKLRLIKQQESLRHQVM 218

  Fly   463 QCTRRDTTLETALNIKLYKRTKRQGLREARATEKLEKQQKLEAERKRRQKHLEFLAAVLQHGKDL 527
            .|.....|:..|:.....:|.|... :..|.||.||:||:.:.||:.:||..::|..|..||:::
pombe   219 HCQPHLRTIVNAVERMSCRRPKLVP-QATRLTEVLERQQRSDRERRLKQKQCDYLQTVCAHGREI 282

  Fly   528 REFHRNNKAQLARMNKAVMNHHANAEREQKKEQERIEKERMRRLMAEDEEGYRKLIDQKKDKRLA 592
            ....:|.:|:..:.|:||:.:|::.|:|:::..||..|:|::.|...|||.|.|||||.||.|:.
pombe   283 NVRTKNAQARAQKANRAVLAYHSHIEKEEQRRAERNAKQRLQALKENDEEAYLKLIDQAKDTRIT 347

  Fly   593 FLLSQTDEYISNLTQMVKQHKDDQMKKKEEEGKRLIQFKKELLMSGEYIGIDEGSIVADMRVHVV 657
            .||.|||.|:.:|...||
pombe   348 HLLRQTDHYLDSLAAAVK----------------------------------------------- 365

  Fly   658 EQCTGKKLTGDDAPMLKHLHRWLNMHPGWDWIDDEEDSCGSNDDHKPKVEEQPTATEDATDKAQA 722
                                                             .:|....|.|.|
pombe   366 -------------------------------------------------VQQSQFGESAYD---- 377

  Fly   723 TGNDEDAKDLITKAKVEDDEYRTEEQTYYSIAHTIHEKVVEQASIMVNGTLKEYQIKGLEWLVSL 787
                   :|:..:...|||    .:..||::||.|.|.|.||.||:|.|.|||||::||:|::||
pombe   378 -------EDMDRRMNPEDD----RKIDYYNVAHNIREVVTEQPSILVGGKLKEYQLRGLQWMISL 431

  Fly   788 YNNNLNGILADEMGLGKTIQTISLVTYLMDRKKVMGPYLIIVPLSTLPNWVLEFEKWAPAVGVVS 852
            |||:||||||||||||||||||||:|:|:::|:..||:|:|||||||.||.:|||:|||::..:.
pombe   432 YNNHLNGILADEMGLGKTIQTISLITHLIEKKRQNGPFLVIVPLSTLTNWTMEFERWAPSIVKIV 496

  Fly   853 YKGSPQGRRLLQNQMRATKFNVLLTTYEYVIKDKAVLAKIQWKYMIIDEGHRMKNHHCKLTQVLN 917
            |||.||.|:.|..|:|.:.|.||||||||:|||:.:|::|:|.||||||||||||...|||..|.
pombe   497 YKGPPQVRKALHPQVRHSNFQVLLTTYEYIIKDRPLLSRIKWIYMIIDEGHRMKNTQSKLTNTLT 561

  Fly   918 THYIAPYRLLLTGTPLQNKLPELWALLNFLLPSIFKSCSTFEQWFNAPFATTG--EKVELNEEET 980
            |:|.:.|||:||||||||.||||||||||:||.||.|..:|::|||.|||.||  :|:||.|||:
pombe   562 TYYSSRYRLILTGTPLQNNLPELWALLNFVLPRIFNSIKSFDEWFNTPFANTGGQDKMELTEEES 626

  Fly   981 ILIIRRLHKVLRPFLLRRLKKEVEHQLPDKVEYIIKCDMSALQRVLYKHMQSKGVLLTDGSEKGK 1045
            :|:||||||||||||||||||:||.:||||||.:|:|.||.||:.||..|:..|:|..   |..|
pombe   627 LLVIRRLHKVLRPFLLRRLKKDVEAELPDKVEKVIRCQMSGLQQKLYYQMKKHGMLYV---EDAK 688

  Fly  1046 HGKGGAKALMNTIVQLRKLCNHPFMFQHIEEKYCDHTGGHGVVSGPDLYRVSGKFELLDRILPKL 1110
            .||.|.|.|.||::||:|:|||||:|:.: |:..|.||    .:...|:||||||||||||||||
pombe   689 RGKTGIKGLQNTVMQLKKICNHPFVFEDV-ERSIDPTG----FNYDMLWRVSGKFELLDRILPKL 748

  Fly  1111 KATNHRVLLFCQMTQCMTIIEDYLGWRQFGYLRLDGTTKAEDRGELLRKFNAKGSDVFVFLLSTR 1175
            ..:.||:|:|.||||.|.|:||||.:||:.||||||:|||:||.:||..||...::|.:||||||
pombe   749 FRSGHRILMFFQMTQIMNIMEDYLHYRQWRYLRLDGSTKADDRSKLLGVFNDPTAEVNLFLLSTR 813

  Fly  1176 AGGLGLNLQTADTVVIFDSDWNPHQDLQAQDRAHRIGQRNEVRVLRLMTVNSVEERILAAARYKL 1240
            ||||||||||||||:|||||||||||||||||||||||..|||:.||:|..||||.|||.|:|||
pombe   814 AGGLGLNLQTADTVIIFDSDWNPHQDLQAQDRAHRIGQTKEVRIYRLITEKSVEENILARAQYKL 878

  Fly  1241 NMDEKVIQAGMFDQKSTGSERQQFLQTILHQDDNEEE--EENEVPDDEMINMMIARSEEEIEIFK 1303
            ::|.||||||.||.|||..||:.||:::|..::.|||  |:.|:.||| :|.::||.::|:.:||
pombe   879 DIDGKVIQAGKFDNKSTPEEREAFLRSLLENENGEEENDEKGELDDDE-LNEILARGDDELRLFK 942

  Fly  1304 RM--DAERKK---EDEEIHPGRERLIDESELPDWLTKDDDEVERFHYQYDEDTILGRGSRQRKEV 1363
            :|  |.||:.   :::|    :||||..||||::..:::.|......|.:.   ||||:|:|..|
pombe   943 QMTEDLERESPYGKNKE----KERLIQVSELPEFYQREEPEKTTDLLQEEP---LGRGARRRTPV 1000

  Fly  1364 DYTDSLTEKEWLKAIDDGAEFDEEEEEDDSKRKRRKRKNRKEESDDDSLIL------KRRR---- 1418
            .|.:::.:.:|:      ||.|.|.|    .|..|.|..|...|.|::..|      |::|
pombe  1001 VYDEAVRDAQWM------AEMDMESE----ARPTRGRPKRNIASVDETPALTLNGKPKKKRGPAP 1055

  Fly  1419 ------RQNLDKRSKKQMHKIMSAVIKHNQDGRTLSEPFMKLPSRQRLPDYYEIIKRPVDIKKIL 1477
                  .::|.:|...:::|.::.:  .:.:||.|::.|::|||::..||||.|||.|:.:..|.
pombe  1056 DTLTSEHRSLLRRVCLEIYKAVNEL--EDDNGRPLNKLFLELPSKKLYPDYYMIIKSPIALDAIR 1118

  Fly  1478 QRIEDCKYADLNELEKDFMQLCQNAQIYNEEASLIYLDSIALQ 1520
            :.|....|..|..::.|.|.:..||:.||||.|.:|.|:..:|
pombe  1119 KHINGTFYKTLEAMKSDLMTMFNNARTYNEEGSFVYEDANKMQ 1161

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
brm	NP_001261906.1	QLQ	173..202	CDD:462622
		Pro-rich	<247..401	CDD:464580
		PTZ00121	<477..651	CDD:173412	51/173 (29%)
		HSA	501..573	CDD:214727	22/71 (31%)
		BRK	650..691	CDD:462196	0/40 (0%)
		PLN03142	739..>1368	CDD:215601	376/637 (59%)
		Bromo_SNF2L2	1425..1530	CDD:99947	33/96 (34%)
snf21	NP_594861.1	HSA	256..328	CDD:214727	22/71 (31%)
		PLN03142	305..>947	CDD:215601	387/761 (51%)
		SnAC	949..1012	CDD:464219	21/69 (30%)
		Bromo_SNF2	1066..1168	CDD:99950	33/98 (34%)