Protein Alignment brm and rad-54.B

DIOPT Version :10

• Sequence 1: NP_001261906.1
• Gene: brm / 39744
• FlyBaseID: FBgn0000212
• Length: 1658
• Species: Drosophila melanogaster
• Sequence 2: NP_001255913.1
• Gene: rad-54.B / 190999
• WormBaseID: WBGene00013792
• Length: 833
• Species: Caenorhabditis elegans
• Alignment Length: 725
• Identity: 194/725 - (26%)
• Similarity: 310/725 - (42%)
• Gaps: 200/725 - (27%)

  Fly   752 SIAHTIHEK----VVEQASIMVNGT-------------LKEYQIKGLEWLVSLY--NNNLNG--- 794
            |.:.||.||    ::.:..|:...|             |:.:|..|::::....  .:..||
 Worm   168 SSSSTIQEKIPPFILNEQDILDRKTTSAVTVDTRFARHLRPHQKSGIQFIFDRLRRGSGKNGGGG 232

  Fly   795 --ILADEMGLGKTIQTISLVTYLMDRKK----VMGPYLIIVPLSTLPNWVLEFEKW-----APAV 848
              ||||:|||||::||::....|:...|    :....|||||.|.:.||..||:||     .|||
 Worm   233 GAILADDMGLGKSLQTMAATWALLKGSKTAQQLANSCLIIVPSSLVNNWKAEFDKWWRLMRFPAV 297

  Fly   849 ------GVVSYKGSPQGRRLLQNQMRATKFNVLLTTYEYVIKDKAVLAKIQWKYMIIDEGHRMKN 907
                  .:.:|          |:.::...:  |:.:|:...:....|..|::..|:.||||::||
 Worm   298 IALTANDITTY----------QSTIKLMPY--LVISYDLAQRHVEKLKIIRFDVMVCDEGHKLKN 350

  Fly   908 HHCKLTQVLNTHYIAPYRLLLTGTPLQNKLPELWALLNFLLPSIFKSCSTFEQWFNAPFATTGEK 972
            ...||.:.|.:..| |.||:|||||:||...|.::||:|:.||:|.|...|.:       ...::
 Worm   351 LDGKLRKTLLSLEI-PRRLILTGTPMQNDFEEFYSLLDFVRPSVFGSIVEFRK-------MCSDR 407

  Fly   973 VELNEEETILIIRRLHKVLRPFLLRRLKKEVE-HQLPDKVEYIIKCDMSALQRVLYKHMQSKGVL 1036
            .|           :|::::...:|||...:|: ..||:|.|||:.|..|.:|    ||:.|:
 Worm   408 PE-----------QLNELIDECMLRRTAADVDLKHLPEKHEYILFCAASPIQ----KHVHSE--- 454

  Fly  1037 LTDGSEKGKHGKGGAKALMNTIVQLRKLCNHP-FMFQHIEEKYCDHTGGHGVVSGPDLYRVSGKF 1100
            :.|      :..|.|.:|   |...|:|.||| .:..::.|| .:.:..|  ...|.|....|..
 Worm   455 ICD------YMTGDALSL---IFFARQLANHPKLLLDNLREK-TEKSKAH--KHSPLLLAFDGAH 507

  Fly  1101 ELLDRILP--------KLKATNHRVLLFCQMTQCMTIIEDYL----------GWRQFGYLRLDGT 1147
                  :|        ||.|....:..|..:.:|..|:.:|:          .:..|..|||||.
 Worm   508 ------MPRGGVKESGKLTALVDMIKCFRLLQECTVIVSNYIETLDMIQQLCEYLNFKVLRLDGK 566

  Fly  1148 TKAEDRGELLRKFNAKGSDVFVFLLSTRAGGLGLNLQTADTVVIFDSDWNPHQDLQAQDRAHRIG 1212
            |:..||.:|:|.||.......:|||||:|||:||||..|..:|:|||||||..|.||..|..|.|
 Worm   567 TQVPDRQKLVRTFNDHRDPSNIFLLSTKAGGVGLNLIGASRLVLFDSDWNPANDQQAMARIWRDG 631

  Fly  1213 QRNEVRVLRLMTVNSVEERILAAARYKLNM-----------------DEKVIQAGMFDQKSTGSE 1260
            |.....:.||:|..::||::|.....|..:                 ||.:.....|...:|...
 Worm   632 QVRPCHIYRLITTGTIEEKMLQRQIKKTGLGCVIDAIEVGDTIATFTDEDLKDIFTFTGSATECN 696

  Fly  1261 RQQFLQT------ILHQDDNEEEEENEVPDDEMINMMIARSEEEIEIFKRMDAERKKEDEEIHPG 1319
            .....:.      :|..:.:||::.::|.::                    |||:
 Worm   697 THDLCECPCDGCGMLENEMDEEDDGDDVVEN--------------------DAEK---------- 731

  Fly  1320 RERLIDESELPDWLTKDDDEVERFHYQYDEDTILGRGSRQRKEVDYTDSLTEKEWLKAIDDGAEF 1384
                ||:|...|.:..||||      :.|::.:         |.|.||.:.|
 Worm   732 ----IDKSGKIDKIDSDDDE------EADDEEL---------EADVTDEVVE------------- 764

  Fly  1385 DEEEEEDDSK 1394
            |.:|..:.:|
 Worm   765 DSQEPPEATK 774

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
brm	NP_001261906.1	QLQ	173..202	CDD:462622
		Pro-rich	<247..401	CDD:464580
		PTZ00121	<477..651	CDD:173412
		HSA	501..573	CDD:214727
		BRK	650..691	CDD:462196
		PLN03142	739..>1368	CDD:215601	189/697 (27%)
		Bromo_SNF2L2	1425..1530	CDD:99947
rad-54.B	NP_001255913.1	HepA	<206..661	CDD:440319	159/510 (31%)