DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17027 and INM1

DIOPT Version :9

Sequence 1:	NP_001261909.1	Gene:	CG17027 / 39742	FlyBaseID:	FBgn0036553	Length:	288	Species:	Drosophila melanogaster
Sequence 2:	NP_011912.1	Gene:	INM1 / 856442	SGDID:	S000001088	Length:	295	Species:	Saccharomyces cerevisiae

Alignment Length:	279	Identity:	86/279 - (30%)
Similarity:	124/279 - (44%)	Gaps:	61/279 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 DIEELYNFIHPLAI-KAGEIL------MEGYEMASKNVSIKGDFYDVVTDYDNKIEDFLMEKILA 65
            |:..:..|:..||. |.|.|:      .:.|::.:.:.|:     |:||..|.::|..:.|.:..
Yeast     4 DLASIEKFLCELATEKVGPIIKSKSGTQKDYDLKTGSRSV-----DIVTAIDKQVEKLIWESVKT 63

  Fly    66 RYPDHKFIGEEETAKNNNVSGELTNAPTWIIDPIDGTSNFIKQIPHVCVSIGLAINKQIVVGVIN 130
            :||..||||||...|...|   :|:.||:||||||||:||:...|..|.|:||.:||:.|||||.
Yeast    64 QYPTFKFIGEESYVKGETV---ITDDPTFIIDPIDGTTNFVHDFPFSCTSLGLTVNKEPVVGVIY 125

  Fly   131 NPVQKKLFTTKLGQGAFCNGKPI-HVSSCESV-----------------------KDANVAYEVS 171
            ||....|.:...|.|...|.|.. :.|..||:                       :.....||..
Yeast   126 NPHINLLVSASKGNGMRVNNKDYDYKSKLESMGSLILNKSVVALQPGSAREGKNFQTKMATYEKL 190

  Fly   172 LL----HVHSVANKHIKRIYHVGLNARRLVAYSCVVDELCMVAAGNLDAFYIEDMYPWDCAAGSL 232
            |.    .||...|        :|.:|..: ||         :|.|.||:::....|.||..||..
Yeast   191 LSCDYGFVHGFRN--------LGSSAMTM-AY---------IAMGYLDSYWDGGCYSWDVCAGWC 237

  Fly   233 LVKEAGGVVTHPFGGPFDI 251
            ::||.||.|.....|.:.|
Yeast   238 ILKEVGGRVVGANPGEWSI 256

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17027	NP_001261909.1	IMPase	12..259	CDD:238817	85/275 (31%)
INM1	NP_011912.1	IMPase	10..267	CDD:238817	85/273 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0483
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54074
OrthoFinder	1	1.000	-	-		FOG0000745
OrthoInspector	1	1.000	-	-		mtm9175
orthoMCL	1	0.900	-	-		OOG6_100401
Panther	1	1.100	-	-	O	PTHR20854
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X706
TreeFam	1	0.960	-	-
	10	9.780