DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17027 and Impa1

DIOPT Version :9

Sequence 1:	NP_001261909.1	Gene:	CG17027 / 39742	FlyBaseID:	FBgn0036553	Length:	288	Species:	Drosophila melanogaster
Sequence 2:	XP_006232213.1	Gene:	Impa1 / 83523	RGDID:	69254	Length:	330	Species:	Rattus norvegicus

Alignment Length:	282	Identity:	105/282 - (37%)
Similarity:	158/282 - (56%)	Gaps:	24/282 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 EELYNFIHPLAIKAGEILMEGYEMASKN---VSIKGDFYDVVTDYDNKIEDFLMEKILARYPDHK 71
            :|..::...||.:|||::.|    |.||   |.||....|:||..|.|:|..||..|..:||.|.
  Rat    59 QECMDYAVILARQAGEMIRE----ALKNKMDVMIKSSPADLVTVTDQKVEKMLMSSIKEKYPYHS 119

  Fly    72 FIGEEETAKNNNVSGE---LTNAPTWIIDPIDGTSNFIKQIPHVCVSIGLAINKQIVVGVINNPV 133
            |||||..|     :||   .|..|||||||||||:||:.:.|.|.||||..:||::..||:.:.|
  Rat   120 FIGEESVA-----AGEKTVFTEQPTWIIDPIDGTTNFVHRFPFVAVSIGFVVNKEMEFGVVYSCV 179

  Fly   134 QKKLFTTKLGQGAFCNGKPIHVSSCESVKDANVAYEVSLL---HVHSVANKHIKRIYHVGLNARR 195
            :.|::|.:.|:||||||:.:.||..|.:..:.:..|:...   ....:...:::|:..:.::..|
  Rat   180 EDKMYTGRKGKGAFCNGQKLRVSQQEDITKSLLVTELGSSRKPETLRIVLSNMERLCSIPIHGIR 244

  Fly   196 LVAYSCVVDELCMVAAGNLDAFYIEDMYPWDCAAGSLLVKEAGGVVTHPFGGPFDIMKPDLICAG 260
            .|..:.|  .:|:||.|..||:|...::.||.|...::|.|||||:....|||||:|...:|.|.
  Rat   245 SVGTAAV--NMCLVATGGADAYYEMGIHCWDMAGAGIIVIEAGGVLLDVTGGPFDLMSRRIIAAS 307

  Fly   261 ----TEKLRKEIEDLLRKGDQE 278
                .|::.||:|.:..:.|.|
  Rat   308 NIALAERIAKELEIIPLQRDDE 329

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17027	NP_001261909.1	IMPase	12..259	CDD:238817	97/255 (38%)
Impa1	XP_006232213.1	IMPase	61..307	CDD:238817	97/256 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338488
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0483
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54074
OrthoDB	1	1.010	-	-		D406919at33208
OrthoFinder	1	1.000	-	-		FOG0000745
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100401
Panther	1	1.100	-	-	O	PTHR20854
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X706
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	11	10.720