Protein Alignment CG17027 and IMPA2

DIOPT Version :10

• Sequence 1: NP_648823.1
• Gene: CG17027 / 39742
• FlyBaseID: FBgn0036553
• Length: 288
• Species: Drosophila melanogaster
• Sequence 2: NP_055029.1
• Gene: IMPA2 / 3613
• HGNCID: 6051
• Length: 288
• Species: Homo sapiens
• Alignment Length: 283
• Identity: 98/283 - (34%)
• Similarity: 161/283 - (56%)
• Gaps: 19/283 - (6%)

  Fly     2 AGVSQADI-----EELYNFIHPLAIKAGEILMEGYEMASKNVSIKGDFYDVVTDYDNKIEDFLME 61
            :|..||.:     ||.:.....||::||:|:.:.. ...|.||.|....|:||:.|:.:||.::.
Human     4 SGEDQAALAAGPWEECFQAAVQLALRAGQIIRKAL-TEEKRVSTKTSAADLVTETDHLVEDLIIS 67

  Fly    62 KILARYPDHKFIGEEETAKNNNVSGE---LTNAPTWIIDPIDGTSNFIKQIPHVCVSIGLAINKQ 123
            ::..|:|.|:||.||..|     ||.   ||::|||||||||||.||:.:.|.|.||||.|:.::
Human    68 ELRERFPSHRFIAEEAAA-----SGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVRQE 127

  Fly   124 IVVGVINNPVQKKLFTTKLGQGAFCNGKPIHVSSCESVKDANVAYEVSLLHVHSVAN---KHIKR 185
            :..|||.:..:::|:|.:.|:||||||:.:.||....:..|.|..|:......:...   .:::|
Human   128 LEFGVIYHCTEERLYTGRRGRGAFCNGQRLRVSGETDLSKALVLTEIGPKRDPATLKLFLSNMER 192

  Fly   186 IYHVGLNARRLVAYSCVVDELCMVAAGNLDAFYIEDMYPWDCAAGSLLVKEAGGVVTHPFGGPFD 250
            :.|...:..|::..|.:.  ||.:|:|..||:|...::.||.||.:::::||||:|....|||.|
Human   193 LLHAKAHGVRVIGSSTLA--LCHLASGAADAYYQFGLHCWDLAAATVIIREAGGIVIDTSGGPLD 255

  Fly   251 IMKPDLICAGTEKLRKEIEDLLR 273
            :|...::.|.|.::...|...|:
Human   256 LMACRVVAASTREMAMLIAQALQ 278

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17027	NP_648823.1	IMPase	12..259	CDD:238817	89/252 (35%)
IMPA2	NP_055029.1	IMPase	19..265	CDD:238817	89/253 (35%)