Protein Alignment CG17027 and IMPA1

DIOPT Version :9

• Sequence 1: NP_001261909.1
• Gene: CG17027 / 39742
• FlyBaseID: FBgn0036553
• Length: 288
• Species: Drosophila melanogaster
• Sequence 2: NP_001138350.1
• Gene: IMPA1 / 3612
• HGNCID: 6050
• Length: 336
• Species: Homo sapiens
• Alignment Length: 282
• Identity: 105/282 - (37%)
• Similarity: 162/282 - (57%)
• Gaps: 22/282 - (7%)

  Fly    10 EELYNFIHPLAIKAGEILMEGY--EMASKNVSIKGDFYDVVTDYDNKIEDFLMEKILARYPDHKF 72
            :|..::...||.:|||::.|..  ||   ||.:|....|:||..|.|:|..|:..|..:||.|.|
Human    65 QECMDYAVTLARQAGEVVCEAIKNEM---NVMLKSSPVDLVTATDQKVEKMLISSIKEKYPSHSF 126

  Fly    73 IGEEETAKNNNVSGE---LTNAPTWIIDPIDGTSNFIKQIPHVCVSIGLAINKQIVVGVINNPVQ 134
            ||||..|     :||   ||:.|||||||||||:||:.:.|.|.||||.|:||:|..||:.:.|:
Human   127 IGEESVA-----AGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGVVYSCVE 186

  Fly   135 KKLFTTKLGQGAFCNGKPIHVSSCESVKDANVAYEVSLLHVHSVAN---KHIKRIYHVGLNARRL 196
            .|::|.:.|:||||||:.:.||..|.:..:.:..|:..........   .::::::.:.::..|.
Human   187 GKMYTARKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRTPETVRMVLSNMEKLFCIPVHGIRS 251

  Fly   197 VAYSCVVDELCMVAAGNLDAFYIEDMYPWDCAAGSLLVKEAGGVVTHPFGGPFDIMKPDLICAG- 260
            |..:.|  .:|:||.|..||:|...::.||.|...::|.|||||:....|||||:|...:|.|.
Human   252 VGTAAV--NMCLVATGGADAYYEMGIHCWDVAGAGIIVTEAGGVLMDVTGGPFDLMSRRVIAANN 314

  Fly   261 ---TEKLRKEIEDLLRKGDQEE 279
               .|::.|||:.:..:.|.|:
Human   315 RILAERIAKEIQVIPLQRDDED 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17027	NP_001261909.1	IMPase	12..259	CDD:238817	97/254 (38%)
IMPA1	NP_001138350.1	IMPase	67..313	CDD:238817	97/255 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144795
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0483
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1410
OMA	1	1.010	-	-		QHG54074
OrthoDB	1	1.010	-	-		D406919at33208
OrthoFinder	1	1.000	-	-		FOG0000745
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100401
Panther	1	1.100	-	-	O	PTHR20854
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X706
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	11	10.670