DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17028 and INM2

DIOPT Version :9

Sequence 1:	NP_001189114.1	Gene:	CG17028 / 39741	FlyBaseID:	FBgn0036552	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	NP_010573.3	Gene:	INM2 / 851881	SGDID:	S000002695	Length:	292	Species:	Saccharomyces cerevisiae

Alignment Length:	245	Identity:	94/245 - (38%)
Similarity:	129/245 - (52%)	Gaps:	23/245 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LEVYYQVSLELVR-KCGPLFLEGFQKPKTDYEVKSAFYDLVTVYDKQIEATLTDGLLKTFPESKI 73
            ||......:||:| |.|||...........|:.|:...||||..|||||:.:.:.|...:|..|.
Yeast     8 LEEVENTFIELLRSKIGPLVKSHAGTNFCSYDDKANGVDLVTALDKQIESIIKENLTAKYPSFKF 72

  Fly    74 IGEEAMANAKTPPELTDAPTWIIDPIDGTNNYVRKIPHCCISVGLAINKELVLGIVYNPSANELY 138
            ||||......|  ::|:.||:|:||||||.|::...|:.|.|:|||...:.|:|:|:||..|:|:
Yeast    73 IGEETYVKGVT--KITNGPTFIVDPIDGTTNFIHGYPYSCTSLGLAEMGKPVVGVVFNPHLNQLF 135

  Fly   139 SAWQGHGAYLNGQPIEVSNAKKINQALVCYEISLIVVSKGR----------DKNVKRLYKLASSA 193
            .|.:|:||:||.|.|:||....|.|.      |||.:..|.          ||.:.....|.|.:
Yeast   136 HASKGNGAFLNDQEIKVSKRPLILQK------SLIALEGGSERTEGSQGNFDKKMNTYKNLLSES 194

  Fly   194 ----TGTRSFGCAALTLCYIAAGRCDAYHVENLKPWDLAGGAVILREAGG 239
                .|.||.|.||:.:||:|:|..|||.......||:..|..||.||||
Yeast   195 GAFVHGFRSAGSAAMNICYVASGMLDAYWEGGCWAWDVCAGWCILEEAGG 244

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17028	NP_001189114.1	IMPase	13..260	CDD:238817	92/242 (38%)
INM2	NP_010573.3	IMPase	13..265	CDD:238817	92/240 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	169	1.000	Domainoid score	I783
eggNOG	1	0.900	-	-		E1_COG0483
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	169	1.000	Inparanoid score	I1019
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54074
OrthoFinder	1	1.000	-	-		FOG0000745
OrthoInspector	1	1.000	-	-		mtm9175
orthoMCL	1	0.900	-	-		OOG6_100401
Panther	1	1.100	-	-	O	PTHR20854
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X706
TreeFam	1	0.960	-	-
	11	10.920