Protein Alignment CG17028 and IMPA2

DIOPT Version :9

• Sequence 1: NP_001189114.1
• Gene: CG17028 / 39741
• FlyBaseID: FBgn0036552
• Length: 284
• Species: Drosophila melanogaster
• Sequence 2: NP_055029.1
• Gene: IMPA2 / 3613
• HGNCID: 6051
• Length: 288
• Species: Homo sapiens
• Alignment Length: 272
• Identity: 101/272 - (37%)
• Similarity: 149/272 - (54%)
• Gaps: 19/272 - (6%)

  Fly    11 EVYYQVSLELVRKCGPLFLEGFQKPKTDYEVKSAFYDLVTVYDKQIEATLTDGLLKTFPESKIIG 75
            |..:|.:::|..:.|.:..:...:.|. ...|::..||||..|..:|..:...|.:.||..:.|.
Human    17 EECFQAAVQLALRAGQIIRKALTEEKR-VSTKTSAADLVTETDHLVEDLIISELRERFPSHRFIA 80

  Fly    76 EEAMAN-AKTPPELTDAPTWIIDPIDGTNNYVRKIPHCCISVGLAINKELVLGIVYNPSANELYS 139
            |||.|: ||.  .||.:|||||||||||.|:|.:.|...:|:|.|:.:||..|::|:.:...||:
Human    81 EEAAASGAKC--VLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGVIYHCTEERLYT 143

  Fly   140 AWQGHGAYLNGQPIEVSNAKKINQALVCYEISLIVVSKGRD--------KNVKRLYKLASSATGT 196
            ..:|.||:.|||.:.||....:::|||..||     ...||        .|::||  |.:.|.|.
Human   144 GRRGRGAFCNGQRLRVSGETDLSKALVLTEI-----GPKRDPATLKLFLSNMERL--LHAKAHGV 201

  Fly   197 RSFGCAALTLCYIAAGRCDAYHVENLKPWDLAGGAVILREAGGRVYHTSGARFDVMKPDCVCTSS 261
            |..|.:.|.||::|:|..|||:...|..||||...||:|||||.|..|||...|:|....|..|:
Human   202 RVIGSSTLALCHLASGAADAYYQFGLHCWDLAAATVIIREAGGIVIDTSGGPLDLMACRVVAAST 266

  Fly   262 EELAKSVIQLIE 273
            .|:|..:.|.::
Human   267 REMAMLIAQALQ 278

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17028	NP_001189114.1	IMPase	13..260	CDD:238817	96/255 (38%)
IMPA2	NP_055029.1	IMPase	19..265	CDD:238817	96/255 (38%)
		Substrate binding	103..106		2/2 (100%)
		Substrate binding	205..207		1/1 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144802
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0483
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54074
OrthoDB	1	1.010	-	-		D406919at33208
OrthoFinder	1	1.000	-	-		FOG0000745
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100401
Panther	1	1.100	-	-	O	PTHR20854
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X706
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	9	8.810