DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17026 and INM1

DIOPT Version :9

Sequence 1:	NP_648820.1	Gene:	CG17026 / 39739	FlyBaseID:	FBgn0036550	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	NP_011912.1	Gene:	INM1 / 856442	SGDID:	S000001088	Length:	295	Species:	Saccharomyces cerevisiae

Alignment Length:	282	Identity:	89/282 - (31%)
Similarity:	127/282 - (45%)	Gaps:	57/282 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAASKSQIEELYDFIYPLAVRAGEILLEGYQNAGKAVALKDG-EFYNVVTAYDNQIEEFLVEKIL 64
            |....:.||:   |:..||......:::......|...||.| ...::|||.|.|:|:.:.|.:.
Yeast     1 MTIDLASIEK---FLCELATEKVGPIIKSKSGTQKDYDLKTGSRSVDIVTAIDKQVEKLIWESVK 62

  Fly    65 ARYPDHKFIGEEDTHKNDNVTKELTDAPTWIIDPIDGTSNFIKQIPHVSVSIGLSIKKQIVLGVV 129
            .:||..||||||...|.:.|   :||.||:||||||||:||:...|....|:||::.|:.|:||:
Yeast    63 TQYPTFKFIGEESYVKGETV---ITDDPTFIIDPIDGTTNFVHDFPFSCTSLGLTVNKEPVVGVI 124

  Fly   130 NNPAQNKLYTAKLGQGAFCNGKPIQVSSCEH------LNDANVA------------------YEV 170
            .||..|.|.:|..|.|...|.|.....|...      ||.:.||                  ||.
Yeast   125 YNPHINLLVSASKGNGMRVNNKDYDYKSKLESMGSLILNKSVVALQPGSAREGKNFQTKMATYEK 189

  Fly   171 CL------LHAPKIRNKHIKRIYHVGSNARRLLAYSAVVDSLCMVAAGNLDAFHIEDMYPWDCAA 229
            .|      :|.  .||        :||:| ..:||         :|.|.||::.....|.||..|
Yeast   190 LLSCDYGFVHG--FRN--------LGSSA-MTMAY---------IAMGYLDSYWDGGCYSWDVCA 234

  Fly   230 GYLLIREAGGVVTHPYGGPFDI 251
            |:.:::|.||.|.....|.:.|
Yeast   235 GWCILKEVGGRVVGANPGEWSI 256

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17026	NP_648820.1	IMPase	11..259	CDD:238817	86/272 (32%)
INM1	NP_011912.1	IMPase	10..267	CDD:238817	86/273 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0483
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54074
OrthoFinder	1	1.000	-	-		FOG0000745
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100401
Panther	1	1.100	-	-	O	PTHR20854
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.780