Protein Alignment CG17026 and IMPA2

DIOPT Version :9

• Sequence 1: NP_648820.1
• Gene: CG17026 / 39739
• FlyBaseID: FBgn0036550
• Length: 284
• Species: Drosophila melanogaster
• Sequence 2: NP_055029.1
• Gene: IMPA2 / 3613
• HGNCID: 6051
• Length: 288
• Species: Homo sapiens
• Alignment Length: 277
• Identity: 97/277 - (35%)
• Similarity: 161/277 - (58%)
• Gaps: 13/277 - (4%)

  Fly     9 EELYDFIYPLAVRAGEILLEGYQNAGKAVALKDGEFYNVVTAYDNQIEEFLVEKILARYPDHKFI 73
            ||.:.....||:|||:|:.:..... |.|:.|... .::||..|:.:|:.::.::..|:|.|:||
Human    17 EECFQAAVQLALRAGQIIRKALTEE-KRVSTKTSA-ADLVTETDHLVEDLIISELRERFPSHRFI 79

  Fly    74 GEEDTHKNDNVTKELTDAPTWIIDPIDGTSNFIKQIPHVSVSIGLSIKKQIVLGVVNNPAQNKLY 138
            .||.........  ||.:|||||||||||.||:.:.|.|:||||.::::::..||:.:..:.:||
Human    80 AEEAAASGAKCV--LTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGVIYHCTEERLY 142

  Fly   139 TAKLGQGAFCNGKPIQVSSCEHLNDANVAYEVCLLHAP---KIRNKHIKRIYHVGSNARRLLAYS 200
            |.:.|:||||||:.::||....|:.|.|..|:.....|   |:...:::|:.|..::..|::..|
Human   143 TGRRGRGAFCNGQRLRVSGETDLSKALVLTEIGPKRDPATLKLFLSNMERLLHAKAHGVRVIGSS 207

  Fly   201 AVVDSLCMVAAGNLDAFHIEDMYPWDCAAGYLLIREAGGVVTHPYGGPFDIMKPDLICAGTETLR 265
            .:  :||.:|:|..||::...::.||.||..::||||||:|....|||.|:|...::.|.|.
Human   208 TL--ALCHLASGAADAYYQFGLHCWDLAAATVIIREAGGIVIDTSGGPLDLMACRVVAASTR--- 267

  Fly   266 AEIEHLIRKADQEKHVG 282
             |:..||.:|.|..:.|
Human   268 -EMAMLIAQALQTINYG 283

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17026	NP_648820.1	IMPase	11..259	CDD:238817	87/250 (35%)
IMPA2	NP_055029.1	IMPase	19..265	CDD:238817	87/251 (35%)
		Substrate binding	103..106		2/2 (100%)
		Substrate binding	205..207		0/1 (0%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144804
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0483
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1598
OMA	1	1.010	-	-		QHG54074
OrthoDB	1	1.010	-	-		D406919at33208
OrthoFinder	1	1.000	-	-		FOG0000745
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100401
Panther	1	1.100	-	-	O	PTHR20854
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	10	9.670