DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17026 and Impa2

DIOPT Version :9

Sequence 1:	NP_648820.1	Gene:	CG17026 / 39739	FlyBaseID:	FBgn0036550	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	NP_757378.1	Gene:	Impa2 / 282636	RGDID:	628692	Length:	290	Species:	Rattus norvegicus

Alignment Length:	277	Identity:	101/277 - (36%)
Similarity:	164/277 - (59%)	Gaps:	13/277 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 EELYDFIYPLAVRAGEILLEGYQNAGKAVALKDGEFYNVVTAYDNQIEEFLVEKILARYPDHKFI 73
            :|.::....||:|||:|:.:..... |.|:.|... .::||..|:::|:.:|.::..|:|.|:||
  Rat    19 DECFEVAVQLALRAGQIIRKALTEE-KHVSTKTSA-ADLVTETDHRVEDLIVSELRKRFPSHRFI 81

  Fly    74 GEEDTHKNDNVTKELTDAPTWIIDPIDGTSNFIKQIPHVSVSIGLSIKKQIVLGVVNNPAQNKLY 138
            .||.|.......  ||.:|||||||||||.||:.:.|.|:||||.::.:::..||:::..:.:||
  Rat    82 AEEATASGAKCV--LTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVHQELEFGVIHHCTEERLY 144

  Fly   139 TAKLGQGAFCNGKPIQVSSCEHLNDANVAYEVCLLHAP---KIRNKHIKRIYHVGSNARRLLAYS 200
            |.:.||||||||:.:|||....|..|.|..|:.....|   |:...:::|:.|..::..|::..|
  Rat   145 TGRRGQGAFCNGQRLQVSRETDLAKALVLTEIGPKRDPDTLKVFLSNMERLLHAKAHGVRVIGSS 209

  Fly   201 AVVDSLCMVAAGNLDAFHIEDMYPWDCAAGYLLIREAGGVVTHPYGGPFDIMKPDLICAGTETLR 265
            .:  :||.:|:|..||::...::.||.||..::||||||:|....|||.|:|...::.|||.
  Rat   210 TL--ALCYLASGAADAYYQFGLHCWDLAAATVIIREAGGIVIDTSGGPLDLMSCRVVAAGTR--- 269

  Fly   266 AEIEHLIRKADQEKHVG 282
             |:..||.:|.|..:.|
  Rat   270 -EMAVLIAQALQTINYG 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17026	NP_648820.1	IMPase	11..259	CDD:238817	91/250 (36%)
Impa2	NP_757378.1	IMPase	21..266	CDD:238817	91/250 (36%)
		Substrate binding. /evidence=ECO:0000250	105..108		2/2 (100%)
		Substrate binding. /evidence=ECO:0000250	207..209		0/1 (0%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338501
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0483
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54074
OrthoDB	1	1.010	-	-		D406919at33208
OrthoFinder	1	1.000	-	-		FOG0000745
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100401
Panther	1	1.100	-	-	O	PTHR20854
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	10	9.720