Protein Alignment CG10516 and SPSB1

DIOPT Version :9

• Sequence 1: NP_648819.2
• Gene: CG10516 / 39738
• FlyBaseID: FBgn0036549
• Length: 342
• Species: Drosophila melanogaster
• Sequence 2: NP_079382.2
• Gene: SPSB1 / 80176
• HGNCID: 30628
• Length: 273
• Species: Homo sapiens
• Alignment Length: 224
• Identity: 59/224 - (26%)
• Similarity: 96/224 - (42%)
• Gaps: 31/224 - (13%)

  Fly    53 WHATDESDAVVTDRD--IIF--HPTYSQGTAIVRGEQALKTNMVHFWEMRVITTLAGTDVMFGIG 113
            |:..|.|..|....|  :||  ||. :|.|..:||:... |..:|.|::.......||..:.|:.
Human    56 WNNNDRSLNVFVKEDDKLIFHRHPV-AQSTDAIRGKVGY-TRGLHVWQITWAMRQRGTHAVVGVA 118

  Fly   114 TESVNLGQFKFHFVSALGTNAQSWGFSYS-GRIQHCGE---------LLPYGQKFSQGCLIGVCL 168
            |....|  ....:.:.:|.|.:|||:... .|:.|.|:         .|...:.|.......|.|
Human   119 TADAPL--HSVGYTTLVGNNHESWGWDLGRNRLYHDGKNQPSKTYPAFLEPDETFIVPDSFLVAL 181

  Fly   169 DRTRGHLEFYLNRRSLGVAYTNVPTDPDVKIYPMVCSTAAKSVIR---LINCTSQPVTLQ---LR 227
            |...|.|.|.::.:.:|||:..:   ...|:||:|.:......||   |.....:|:.|.   .|
Human   182 DMDDGTLSFIVDGQYMGVAFRGL---KGKKLYPVVSAVWGHCEIRMRYLNGLDPEPLPLMDLCRR 243

  Fly   228 SFQ-ALSRQPLKLAELRQMPGLKGIMQSY 255
            |.: ||.|:  :|.|:..:| |...:::|
Human   244 SVRLALGRE--RLGEIHTLP-LPASLKAY 269

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10516	NP_648819.2	SPRY_SOCS3	51..233	CDD:293936	52/200 (26%)
SPSB1	NP_079382.2	SPRY_SOCS1-2-4	54..227	CDD:293963	46/177 (26%)
		SOCS_SSB1	232..273	CDD:239713	12/41 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3953
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810