DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10516 and spsb4b

DIOPT Version :9

Sequence 1:	NP_648819.2	Gene:	CG10516 / 39738	FlyBaseID:	FBgn0036549	Length:	342	Species:	Drosophila melanogaster
Sequence 2:	NP_001003474.1	Gene:	spsb4b / 445080	ZFINID:	ZDB-GENE-040801-213	Length:	281	Species:	Danio rerio

Alignment Length:	210	Identity:	59/210 - (28%)
Similarity:	87/210 - (41%)	Gaps:	40/210 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 WHATDES-DAVVTDRD-IIF--HPTYSQGTAIVRGEQALKTNMVHFWEMRVITTLAGTDVMFGIG 113
            |:..|.| :..:.|.| :.|  ||. :|.|..|||:... |..:|.|.:|......||..:.|:.
Zfish    59 WNPDDRSPNLFIKDDDRLTFHRHPV-AQSTDCVRGKTGF-TRGLHAWSLRWPVRQRGTHAVVGVA 121

  Fly   114 TESVNLGQFKFHFVSAL-GTNAQSWGFSYS-GRIQH-----CGELLPYGQ---------KFSQGC 162
            |....|....:   ||| |::|:|||:... ||:.|     .|...||.:         .||...
Zfish   122 TSLATLRAVGY---SALVGSDAESWGWDLGRGRLYHDRKSRSGPAPPYPEFVEDEDEEGTFSVPE 183

  Fly   163 LIGVCLDRTRGHLEFYLNRRSLGVAYTNVPTDPDVKIYPMVCSTAAKSVIRLINCTSQPVTLQLR 227
            .|.|.||...|.|.|..:...||||:..:   ...::||:|.:...       :|     .:.:.
Zfish   184 EILVVLDMDEGTLGFCADGNYLGVAFRGL---KGKRLYPIVSAVWG-------HC-----EVSMN 233

  Fly   228 SFQALSRQPLKLAEL 242
            ....|..:||.|.||
Zfish   234 YINGLDPEPLPLMEL 248

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10516	NP_648819.2	SPRY_SOCS3	51..233	CDD:293936	53/199 (27%)
spsb4b	NP_001003474.1	SPRY_SOCS1-2-4	57..235	CDD:293963	53/195 (27%)
spsb4b	NP_001003474.1	SOCS_SSB4	240..281	CDD:239712	5/9 (56%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3953
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810