DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10516 and Spsb2

DIOPT Version :9

Sequence 1:	NP_648819.2	Gene:	CG10516 / 39738	FlyBaseID:	FBgn0036549	Length:	342	Species:	Drosophila melanogaster
Sequence 2:	NP_001009660.1	Gene:	Spsb2 / 297592	RGDID:	1310854	Length:	264	Species:	Rattus norvegicus

Alignment Length:	174	Identity:	43/174 - (24%)
Similarity:	76/174 - (43%)	Gaps:	19/174 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 WHATDESDAV-VTDRDIIF--HPTYSQGTAIVRGEQALKTNMVHFWEMRVITTLAGTDVMFGIGT 114
            |:..|.|:.: |.:..:.|  .|. :|.|..|||::.....: |.||:.......||..:.|:.|
  Rat    48 WNPKDCSENIDVKEGGLCFERRPV-AQSTDGVRGKRGYSRGL-HAWEISWPLEQRGTHAVVGVAT 110

  Fly   115 ESVNLGQFKFHFVSALGTNAQSWGFSYS-GRIQHCGELL--------PYGQKFSQGCLIGVCLDR 170
            ....|.  ..|:.:.||:|::|||:... |::.|..:.|        |.|::......:.|.||.
  Rat   111 ALAPLQ--ADHYAALLGSNSESWGWDIGRGKLYHQSKGLEAPQYPAGPQGEQLVVPERLLVVLDM 173

  Fly   171 TRGHLEFYLNRRSLGVAYTNVPTDPDVKIYPMVCSTAAKSVIRL 214
            ..|.|.:.:....||.|:..:   ....:||.|.:...:..:|:
  Rat   174 EEGTLGYSIGGTYLGPAFRGL---KGRTLYPSVSAVWGQCQVRI 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10516	NP_648819.2	SPRY_SOCS3	51..233	CDD:293936	43/174 (25%)
Spsb2	NP_001009660.1	SPRY_SOCS1-2-4	46..217	CDD:293963	43/174 (25%)
Spsb2	NP_001009660.1	SOCS_SSB2	223..264	CDD:239689
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3953
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810