DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10516 and spsb-1

DIOPT Version :9

Sequence 1:	NP_648819.2	Gene:	CG10516 / 39738	FlyBaseID:	FBgn0036549	Length:	342	Species:	Drosophila melanogaster
Sequence 2:	NP_497321.3	Gene:	spsb-1 / 266876	WormBaseID:	WBGene00021597	Length:	483	Species:	Caenorhabditis elegans

Alignment Length:	215	Identity:	53/215 - (24%)
Similarity:	87/215 - (40%)	Gaps:	37/215 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 WHATDES-DAVVTDRD-IIF--HPTYSQGTAIVRGEQALKTNMVHFWEMRVITTLAGTDVMFGIG 113
            |:..|.| :..|.|.| ..|  ||. :|.|..:||:....... |.|::.......||..:.|:.
Worm   133 WNPEDRSLNIFVKDEDKFTFHRHPV-AQSTDCIRGKMGYSRGF-HVWQIEWPERQRGTHAVVGVA 195

  Fly   114 TESVNLGQFKFH---FVSALGTNAQSWGFSYSGRIQH--CGELLPYGQKFSQG-----------C 162
            |::..|     |   :.:.:||..:|:|:..:.|..|  ....:.:...||..           |
Worm   196 TKNAPL-----HAAGYTALIGTTDESYGWDITRRECHHDSKHTMTWRYPFSNSRDVYNVPDKFYC 255

  Fly   163 LIGVCLDRTRGHLEFYLNRRSLGVAYTNVPTDPDVKIYPMVCSTAAKSVIRLINCTSQPVTLQLR 227
            :    ||...|::.|..:...||||:.|:   ....:||:|.:......|.:....|  :..:|.
Worm   256 I----LDMDEGYMAFATDDEFLGVAFRNL---KGKTLYPIVAAVWGHCEISMRYLGS--LERELI 311

  Fly   228 SFQALS-RQPLKLAELRQMP 246
            ||.:.| ..|.:|..||..|
Worm   312 SFDSSSPTPPRRLPPLRPPP 331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10516	NP_648819.2	SPRY_SOCS3	51..233	CDD:293936	47/199 (24%)
spsb-1	NP_497321.3	SPRY_SOCS1-2-4	131..303	CDD:293963	43/183 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910